2,3-diisopropylsuccinate diisobutyl ester | 303067-90-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2,3-diisopropylsuccinate diisobutyl ester
• 英文别名: Butanedioic acid, 2,3-bis(1-methylethyl)-, bis(2-methylpropyl) ester；bis(2-methylpropyl) 2,3-di(propan-2-yl)butanedioate
• CAS: 303067-90-5
• 化学式: C₁₈H₃₄O₄
• 分子量: 314.466
• InChiKey: WNVMVIYFKFGESM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  22
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• 4H-THIENO[3,2-C]CHROMENE-BASED INHIBITORS OF NOTUM PECTINACETYLESTERASE AND METHODS OF THEIR USE
  申请人：BARBOSA Joseph

  公开号：US20120302562A1

  公开（公告）日：2012-11-29

  Compounds that may be used to inhibit Notum Pectinacetylesterase are described, as well as compositions comprising them, and methods of their use to treat diseases and disorders affecting bone.

  描述了可以用来抑制Notum果胶乙酰酯酶的化合物，以及包含它们的组合物，以及它们用于治疗影响骨骼的疾病和紊乱的方法。
• Catalyst for olefin polymerization and use of the same
  申请人：Gao Mingzhi

  公开号：US20060142146A1

  公开（公告）日：2006-06-29

  The present application discloses a catalyst for olefin polymerization, comprising a product of the following components: (A) solid titanium-containing catalyst component comprising magnesium, titanium and halogen as essential components; (B) organo-aluminum compound catalyst component, and (C) silicon ether compound catalyst component, the silicon ether compound being represented by a general formula (I): wherein R 1 -R 12 and A are as defined in the description.

  本申请公开了一种用于烯烃聚合的催化剂，包括以下组分的产物：（A）固体钛催化剂组分，包括镁、钛和卤素作为必需组分；（B）有机铝化合物催化剂组分；（C）硅醚化合物催化剂组分，其中硅醚化合物由通式（I）表示：其中R1-R12和A如描述中所定义。
• Propylene polymers
  申请人：Morini Giampiero

  公开号：US20050032633A1

  公开（公告）日：2005-02-10

  The present invention relates to a solid catalyst component for the polymerization of olefins CH 2 ═CHR in which R is hydrogen or a hydrocarbon radical with 1-12 carbon atoms, comprising Mg, Ti, halogen and an electron donor selected from substituted succinates of a particular formula. Said catalyst components when used in the polymerization of olefins, and in particular of propylene, are capable to give polymers in high yields and with high isotactic index expressed in terms of high xylene insolubility.

  本发明涉及一种用于聚合烯烃CH2═CHR（其中R为氢或具有1-12个碳原子的碳氢基团）的固体催化剂组分，包括镁、钛、卤素和从特定公式的取代琥珀酸酯中选择的电子给体。当在聚合烯烃，特别是丙烯的聚合中使用该催化剂组分时，能够以高收率和以高二甲苯不溶性表示的高同构指数给出聚合物。
• PROCESS FOR PREPARING 2,3-DI-NON-STRAIGHT-ALKYL-2-CYANOSUCCINIC ACID DIESTERS
  申请人：Xie Lunjia

  公开号：US20120046490A1

  公开（公告）日：2012-02-23

  A process for preparing 2,3-di(non-linear-alkyl)-2-cyanosuccinate compounds, especially 2,3-diisopropyl-2-cyanosuccinate compounds, and processes for preparing 2,3-di(non-linear-alkyl)succinic acids and esters thereof by using the 2,3-di-non-linear propyl-2-cyanosuccinate compounds as intermediates are disclosed.

  本发明揭示了一种制备2,3-二(非线性烷基)-2-氰基琥珀酸酯化合物的方法，特别是2,3-二异丙基-2-氰基琥珀酸酯化合物的方法，并且通过使用2,3-二(非线性烷基)丙二酸及其酯类的制备方法，以2,3-二非线性丙基-2-氰基琥珀酸酯化合物作为中间体。
• PROCESS FOR PREPARING DI-SUBSTITUTED SUCCINATES
  申请人：Sainani Jaiprakash Brijlal

  公开号：US20140194647A1

  公开（公告）日：2014-07-10

  The invention relates to a process for preparing (2,3) disubstituted succinates that allows (2,3) disubstituted succinates to be obtained in good purity and with acceptable reaction yields. The (2) and (3) substitutions may be the same or different. The process comprises reacting a haloacetate with a malonic acid ester into a tricarboxylate, which is further reacted to a (2,3) disubstituted tricarboxylate, hydrolysed, decarboxylated and optionally esterified. Esterified (2,3) disubstituted succinic esters may be used as internal donor in Ziegler-Natta type catalysts for the polymerisation of olefins.

  本发明涉及一种制备（2,3）二取代琥珀酸盐的方法，该方法可使（2,3）二取代琥珀酸盐以良好的纯度和可接受的反应产量获得。 （2）和（3）的取代基可以相同也可以不同。该方法包括将卤代酸酯与丙二酸酯反应成三羧酸酯，进一步反应成（2,3）二取代三羧酸酯，水解，脱羧和可选酯化。酯化的（2,3）二取代琥珀酸酯可以用作Ziegler-Natta型催化剂中的内部给体，用于烯烃的聚合。