Pyridazino<4,5-c>pyridazin | 253-74-7

• 分子结构分类: 有机化合物 - 有机杂环化合物
• 英文名称: Pyridazino<4,5-c>pyridazin
• 英文别名: pyridazino[4,5-c]pyridazine；Pyridazino[3,4-d]pyridazine
• CAS: 253-74-7
• 化学式: C₆H₄N₄
• 分子量: 132.125
• InChiKey: YXBOXLOZVKXYJZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.9
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  51.6
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• [EN] INHIBITORS OF CD40-CD154 BINDING<br/>[FR] INHIBITEURS DE LIAISON CD40-CD154
  申请人：TONIX PHARMACEUTICALS HOLDING CORP

  公开号：WO2020210831A1

  公开（公告）日：2020-10-15

  Disclosed herein are compounds including pharmaceutically acceptable salts, esters, prodrugs, hydrates and tautomers thereof which modulate the interactions of CD-40-CD40L. The compounds are useful for treating, ameliorating or preventing an autoimmune disease, inflammatory disease, or other immune-related disease in a patient in need of treatment.

  本文披露了包括药用可接受的盐、酯、前药、水合物和互变异构体在内的化合物，这些化合物调节CD-40-CD40L的相互作用。这些化合物可用于治疗、改善或预防患有自身免疫疾病、炎症性疾病或其他免疫相关疾病的患者。
• Electrochromic devices
  申请人：CHEVRON RESEARCH AND TECHNOLOGY COMPANY

  公开号：EP0145337A2

  公开（公告）日：1985-06-19

  An electrochromic device (10) incorporates a reversibly colour-changing organic polymer film (20) as part of the display electrode. The display polymer film (20) is capable of undergoing reversible oxidation and/or reduction to a charged, coloured, conductive state. Upon reversing the charge, the polymer returns to its virgin colour. The display films are comprised of linear fused heterocyclic ring systems, optionally with connecting units, or linear monocyclic ring systems and connecting units. The device requires low currents to operate and switch from the virgin state to the coloured state. It also can optionally be operated to exhibit several colours.

  一种电致变色装置（10）将可逆变色有机聚合物薄膜（20）作为显示电极的一部分。 显示聚合物薄膜（20）能够进行可逆氧化和/或还原，变成带电、有色、导电的状态。 一旦电荷反转，聚合物就会恢复原色。 显示薄膜由线性融合杂环环系统（可选择带连接单元）或线性单环环系统和连接单元组成。 该装置只需较低的电流即可运行并从原色状态切换到有色状态。 它还可选择运行以显示多种颜色。
• RECHARGEABLE METAL OR METAL-ION CELL
  申请人：Solvay SA

  公开号：EP2641288A1

  公开（公告）日：2013-09-25
• AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES
  申请人：Flexenable Limited

  公开号：EP3052506B1

  公开（公告）日：2020-06-03
• INHIBITORS OF CD40-CD154 BINDING
  申请人：Tonix Pharmaceuticals Holding Corp.

  公开号：EP3952853A1

  公开（公告）日：2022-02-16