2'-oxo-2'-deoxy-uridine | 16731-31-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 2'-oxo-2'-deoxy-uridine
• 英文别名: 2,2'-anhydro-1-β-D-arabinofuranosyluracil；2'-Ketouridin；1-[(2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-oxooxolan-2-yl]pyrimidine-2,4-dione
• CAS: 16731-31-0
• 化学式: C₉H₁₀N₂O₆
• 分子量: 242.188
• InChiKey: GSGLDXGMCHRNTG-UEYSZJFGSA-N

物化性质

• 密度：
  1.666±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -1.9
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  116
• 氢给体数：
  3
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  2'-oxo-2'-deoxy-uridine 在 吡啶 、 氢氟酸 作用下， 生成 2'-氟-2'-脱氧尿苷
  参考文献：
  名称：

  [EN] OLIGONUCLEOTIDES HAVING MODIFIED NUCLEOSIDE UNITS
  [FR] OLIGONUCLEOTIDES A UNITES NUCLEOSIDIQUES MODIFIEES

  摘要：

  揭示了包含一个或多个修饰核苷酸单元的寡核苷酸和寡核苷苷。这些寡核苷酸和寡核苷苷特别适用作为反义物质、核酶、适配体、siRNA物质、探针和引物，或者在与RNA杂交时，作为RNA裂解酶（包括RNase H和dsRNase）的底物。

  公开号：

  WO2003099840A1

文献信息

• INCREASING LIPID PRODUCTION IN OLEAGINOUS YEAST
  申请人：Novogy Inc.

  公开号：EP3149153A1

  公开（公告）日：2017-04-05
• [EN] INCREASING LIPID PRODUCTION IN OLEAGINOUS YEAST<br/>[FR] AUGMENTATION DE LA PRODUCTION DE LIPIDES DANS LA LEVURE OLÉAGINEUSE
  申请人：NOVOGY INC

  公开号：WO2015184303A1

  公开（公告）日：2015-12-03

  Disclosed axe methods and compositions for increasing the triacylglycerol content of a cell by increasing the activity of a type I diacylglycerol acyltransferase (i.e., DGA2) and increasing the activity of a type 2 diacylglycerol acyltransferase (i.e., DGA.1 ), In some embodiments, the triacylglycerol content of a cell is also modified my decreasing the activity of a triacylglycerol lipase in the same cell. Also disclosed are methods and compositions for increasing the triacylglycerol content of a cell by increasing the activity of a type 1 diacylglycerol acyltransferase (i.e., DGA2), or by increasing the activity of a type 3 diacylglycerol acyltransferase (i.e., DGA3).
• [EN] EXPRESSION OF HETEROLOGOUS ENZYMES IN YEAST FOR FLAVOURED ALCOHOLIC BEVERAGE PRODUCTION<br/>[FR] EXPRESSION D'ENZYMES HÉTÉROLOGUES DANS LA LEVURE POUR LA PRODUCTION DE BOISSON ALCOOLISÉE AROMATISÉE
  申请人：DANSTAR FERMENT AG

  公开号：WO2019171230A1

  公开（公告）日：2019-09-12

  The present disclosure concerns recombinant yeast host cells expressing one or more heterologous polypeptide for making a flavour compound and a native ethanol production pathway. The recombinant yeast host cells can be used in a subsequent production process to make flavoured alcoholic beverage products, such as beers.