4-联苯基-6-苯甲酸苯酯 | 17064-47-0

• 物质功能分类: 分析化学 - 标准品 - 光谱标准品
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 4-联苯基-6-苯甲酸苯酯
• 中文别名: 2-(4-联苯基)-6-苯基苯丙噁唑；2-(4-联苯)-6-苯基苯并噁唑
• 英文名称: 2-(4-biphenylyl)-6-phenylbenzoxazole
• 英文别名: 2-(biphenyl-4-yl)-6-phenylbenzoxazole；2-(4-biphenyl-3-ido)-5-phenylbenzoxazole；2-biphenyl-4-yl-6-phenyl-benzooxazole；2-(4-biphenylyl)-6-phenyl-1,3-benzoxazole；6-phenyl-2-(4-phenylphenyl)-1,3-benzoxazole
• CAS: 17064-47-0
• 化学式: C₂₅H₁₇NO
• mdl: MFCD00005768
• 分子量: 347.416
• InChiKey: WISWLZYHZLVSMO-UHFFFAOYSA-N

物化性质

• 熔点：
  198-199 °C(lit.)
• 沸点：
  481.96°C (rough estimate)
• 密度：
  1.1510 (rough estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  27
• 可旋转键数：
  3
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  26
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 安全说明：
  S22,S24/25
• WGK Germany：
  3
• 海关编码：
  2934999090

制备方法与用途

用途：适宜用作激光染料。

反应信息

• 作为反应物：
  描述：

  4-联苯基-6-苯甲酸苯酯 、 氯化铑(三水) 在 ethylenediamine 作用下， 以 乙二醇甲醚 为溶剂， 以56%的产率得到bis[2-(biphenyl-4-yl-3-ido)-6-phenylbenzoxazole]ethylenediaminerhodium(III) chloride
  参考文献：
  名称：

  Cyclometalated Pd(ii) and Rh(iii) complexes with ethylenediamine based on 2-(4-biphenyl)-5-phenylbenzoxazole luminophore

  摘要：

  DOI：

  10.1134/s1070363211110259

文献信息

• Chemical address tags
  申请人：Rosania R. Gustavo

  公开号：US20070111251A1

  公开（公告）日：2007-05-17

  The present invention provides methods and compositions related to the fields of chemoinformatics, chemogenomics, drug discovery and development, and drug targeting. In particular, the present invention provides subcellular localization signals (e.g., chemical address tags) that influence (e.g., direct) subcellular and organelle level localization of associated compounds (e.g., drugs and small molecule therapeutics, radioactive species, dyes and imagining agents, proapoptotic agents, antibiotics, etc) in target cells and tissues. The compositions of the present invention modulate the pharmacological profiles of associated compounds by influencing the compound's accumulation, or exclusion, from subcellular loci such as mitochondria, endoplasmic reticulum, cytoplasm, vesicles, granules, nuclei and nucleoli and other subcellular organelles and compartments. The present invention also provides methods for identifying chemical address tags, predicting their targeting characteristics, and for rational designing chemical libraries comprising chemical address tags.

  本发明提供与化学信息学、化学基因组学、药物发现和开发以及药物靶向相关的方法和组合物。特别地，本发明提供亚细胞定位信号（例如，化学地址标签），其影响（例如，指导）相关化合物（例如，药物和小分子治疗剂、放射性物质、染料和成像剂、促凋亡剂、抗生素等）在目标细胞和组织中的亚细胞和细胞器水平定位。本发明的组分通过影响化合物在线粒体、内质网、细胞质、囊泡、颗粒、细胞核和核仁以及其他亚细胞器和区域等亚细胞位置的累积或排除，调节相关化合物的药理特性。本发明还提供了识别化学地址标签、预测其靶向特性以及合理设计包含化学地址标签的化学库的方法。
• Organic electroluminescent devices having improved power conversion efficiencies
  申请人：EASTMAN KODAK COMPANY (a New Jersey corporation)

  公开号：EP0120673A2

  公开（公告）日：1984-10-03

  Electroluminescent devices are disclosed comprising a hole-injecting zone and an adjacent organic luminescent zone, having a combined thickness no greater than about 1 micron, which have a power conversion efficiency of at least 9 x 10-5 w/w. Preferred electron-transporting compounds for the luminescentzone provide a maximum electroluminescent quantum efficiency of at least 5 ×10-4 photons/electron when tested as described.

  已公开的电致发光器件包括一个空穴注入区和一个相邻的有机发光区，其总厚度不超过约 1 微米，功率转换效率至少为 9 x 10-5 w/w。用于发光区的优选电子传递化合物在进行所述测试时，可提供至少 5 ×10-4 光子/电子的最大电致发光量子效率。
• Polylactide compounds as sensitivity enhancers for radiation sensitive mixtures
  申请人：OCG MICROELECTRONIC MATERIALS, INC.

  公开号：EP0561625A1

  公开（公告）日：1993-09-22

  A radiation-sensitive composition comprises an admixture in a solvent of: at least one alkali-soluble binder resin, at least one photoactive compound and an effective sensitivity enhancing amount of at least one polylactide compound; the amount of said binder resin being about 60 to 95% by weight, the amount of said photoactive component being about 5% to about 40% by weight, based on the total solids content of said radiation-sensitive compostion.

  一种辐射敏感性组合物包括以下物质在溶剂中的混合物：至少一种碱溶性粘合剂树脂、至少一种光活性化合物和有效提高敏感性的至少一种聚乳酸化合物；根据所述辐射敏感性组合物的总固体含量，所述粘合剂树脂的含量约为 60% 至 95%（按重量计），所述光活性成分的含量约为 5%至 40%（按重量计）。
• High ortho-ortho bonded novolak binder resins and their use in radiation-sensitive compositions
  申请人：OCG MICROELECTRONIC MATERIALS, INC.

  公开号：EP0623633A2

  公开（公告）日：1994-11-09

  A phenolic novolak composition prepared by a process characterized by the steps of: (1) reacting a first phenolic monomer comprising a major portion of at least one trifunctional phenolic monomer with a first aldehyde source in the absence of a catalyst at a reaction temperature from about 100°C to about 200°C and at a reaction pressure of about 2 to about 15 atmospheres to form a phenolic oligomer having a weight average molecular weight from about 500 to about 2,000, having ortho-ortho bonding of about 55% to about 75% of the methylene bonds between the phenolic moieties; and having a time to clear of less than 125 seconds per micron; wherein the mole ratio of said first aldehyde source to said first phenolic monomer is from about 0.3:1.0 to about 0.55:1.0; and (2) then reacting said oligomer with an optional second phenolic source and a second aldehyde source at a temperature from about 80°C to about 150°C to form a phenolic novolak having a weight average molecular weight of 3,000 to 40,000, having ortho-ortho bonding of between 50% and 70% of the methylene bonds between the phenolic moieties, and having a time to clear of at least 20 seconds per micron; wherein the mole ratio of said second aldehyde source to said total phenolic moieties is less than about 0.8:1.0.

  一种酚醛树脂组合物，其制备过程包括以下步骤 (1) 在没有催化剂的情况下，在反应温度约为 100°C 至约 200°C，反应压力约为 2 至约 15 个大气压的条件下，使包含至少一种三官能酚类单体的主要部分的第一酚类单体与第一醛源反应，以形成酚类低聚物，该酚类低聚物的重量平均分子量约为 500 至约 2,000，酚基之间的亚甲基键的正交键合率约为 55% 至约 75%；其中所述第一醛源与所述第一酚单体的摩尔比为约 0.3:1.0至约0.55:1.0；以及 (2) 然后将所述低聚物与任选的第二酚源和第二醛源在约80℃至约150℃的温度下反应，以形成酚醛新酯，其重量平均分子量为3,000至40,000，酚基之间50%至70%的亚甲基键为正交键，且每微米的透明时间至少为20秒；其中所述第二醛源与所述酚基总量的摩尔比小于约0.8:1.0。
• Selected trinuclear novolak oligomers and their use in photo-active compounds and radiation sensitive mixtures
  申请人：OCG MICROELECTRONIC MATERIALS, INC.

  公开号：EP0685766A1

  公开（公告）日：1995-12-06

  A trinuclear novolak oligomer characterized by the formula (I): wherein each X is selected from the group consisting of hydrogen, hydroxyl group and halide group and Y is selected from the group consisting of a lower alkyl group having 1-4 carbon atoms and a halogen atom.

  一种三核新酚醛低聚物，其特征为式 (I)： 其中每个 X 选自氢、羟基和卤化物基团组成的组，Y 选自具有 1-4 个碳原子的低级烷基和卤素原子组成的组。

表征谱图