(R)-2-(4-(carboxymethoxy)phenoxy)propanoic acid | 1376513-78-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (R)-2-(4-(carboxymethoxy)phenoxy)propanoic acid
• 英文别名: (2R)-2-[4-(carboxymethoxy)phenoxy]propanoic acid
• CAS: 1376513-78-8
• 化学式: C₁₁H₁₂O₆
• 分子量: 240.213
• InChiKey: OXCNECGKTLQFET-SSDOTTSWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  17
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  93.1
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  1,10-菲罗啉 、 (R)-2-(4-(carboxymethoxy)phenoxy)propanoic acid 、 copper(II) acetate monohydrate 以 甲醇 、 水 为溶剂， 反应 1.0h， 以53%的产率得到Cu2(L)2(phen)4(H2O)13
  参考文献：
  名称：

  Syntheses and properties of two chiral multidentate carboxylate copper coordination compounds

  摘要：

  A chiral ligand, (R)-2-(4-(carboxymethoxy)phenoxy) propanoic acid, is employed as building block to construct two chiral coordination compounds, [Cu(L)(bipy)(H2O)] (1) and [Cu-2(L)(2)(phen)(4)(H2O)(13)] (2), by the solvent-thermal method and the volatilization method, respectively. The compounds are characterized by single-crystal X-ray diffraction (XRD), IR spectra, XRD, TGA, and circular dichroism spectra. Compound 1 is comprised of right-handed helical chains and 2 shows a separated structure, both of which extend to 3-D supramolecular framework by hydrogen bonds and pi . . . pi interactions. CD indicates both compounds retain original stereo character with strong fluorescence at room temperature.

  DOI：

  10.1080/00958972.2012.735363
• 作为产物：
  描述：

  在 盐酸 作用下， 以 乙醇 、 水 为溶剂， 反应 6.0h， 以94%的产率得到(R)-2-(4-(carboxymethoxy)phenoxy)propanoic acid
  参考文献：
  名称：

  Syntheses and properties of two chiral multidentate carboxylate copper coordination compounds

  摘要：

  A chiral ligand, (R)-2-(4-(carboxymethoxy)phenoxy) propanoic acid, is employed as building block to construct two chiral coordination compounds, [Cu(L)(bipy)(H2O)] (1) and [Cu-2(L)(2)(phen)(4)(H2O)(13)] (2), by the solvent-thermal method and the volatilization method, respectively. The compounds are characterized by single-crystal X-ray diffraction (XRD), IR spectra, XRD, TGA, and circular dichroism spectra. Compound 1 is comprised of right-handed helical chains and 2 shows a separated structure, both of which extend to 3-D supramolecular framework by hydrogen bonds and pi . . . pi interactions. CD indicates both compounds retain original stereo character with strong fluorescence at room temperature.

  DOI：

  10.1080/00958972.2012.735363