| 1415039-29-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• CAS: 1415039-29-0
• 化学式: C₃₆H₂₃NO₇S
• 分子量: 613.647
• InChiKey: NAUXZJXMPNLMBR-MUUNZHRXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.92
• 重原子数：
  45.0
• 可旋转键数：
  8.0
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  118.05
• 氢给体数：
  1.0
• 氢受体数：
  7.0

反应信息

• 作为反应物：
  描述：

  1,6-己二胺 、 在 三乙胺 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 以70%的产率得到
  参考文献：
  名称：

  Homochiral and meso Figure Eight Knots and a Solomon Link

  摘要：

  A homochiral naphthalenediimide-based building block forms in water a disulfide library of macrocycles containing topological isomers. We attempted to identify each of these isomers, and explored the mechanisms leading to their formation. The two most abundant species of the library were assigned as a topologically chiral Solomon link (60% of the library, as measured by highperformance liquid chromatography (HPLC)) and a topologically achiral figure eight knot (18% by HPLC), competing products with formally different geometries but remarkably similar 4-fold symmetries. In contrast, a racemic mixture of building blocks gives the near-quantitative formation of another new and more stable structure, assigned as a mesa figure eight knot. Taken together, these results seem to uncover a correlation between the point chirality of the building block used and the topological chirality of the major structure formed. These and the earlier discovery of a trefoil knot also suggest that the number of rigid components in the building block may translate into corresponding knot symmetry and could set the basis of a new strategy for constructing complex topologies.

  DOI：

  10.1021/ja4125884

文献信息

• High-Yielding Synthesis of Chiral Donor–Acceptor Catenanes
  作者：Mehrafarin Eilbigi Dehkordi、Vijay Luxami、G. Dan Pantoş

  DOI：10.1021/acs.joc.8b01629

  日期：2018.10.5

  We report the synthesis of [2]catenanes (Hopf links) in water utilizing disulfides and aromatic donor–acceptor interactions. The electron-rich dialkoxynaphthalene (DN) building blocks interact with electron-deficient naphthalenediimide (NDI) moieties connected by a polyamine chain. We study the effect of the polyamine linkers on the behavior of the library. The polyamine’s length and the number of

  我们报道了利用二硫化物和芳香族供体-受体相互作用在水中合成[2] catenanes（霍夫链）的方法。富电子的二烷氧基萘（DN）构件与通过多胺链连接的缺电子的萘二酰亚胺（NDI）部分相互作用。我们研究了多胺接头对文库行为的影响。多胺的长度和链中氮原子的数量会影响文库的分布，在某些情况下会导致链烷烃的组装，产率高达93％。