tyrosylalanine

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: tyrosylalanine
• 英文别名: 2-{[2-Ammonio-3-(4-hydroxyphenyl)propanoyl]amino}propanoate；2-[[2-azaniumyl-3-(4-hydroxyphenyl)propanoyl]amino]propanoate
• 化学式: C₁₂H₁₆N₂O₄
• mdl: MFCD03548046
• 分子量: 252.27
• InChiKey: NLKUJNGEGZDXGO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.1
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.333
• 拓扑面积：
  113
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• Novel peptide-forming enzyme gene
  申请人：Ajinomoto Co., Inc.

  公开号：US20040204577A1

  公开（公告）日：2004-10-14

  DNA and recombinant DNA that encode a peptide-forming enzyme, a method for producing a peptide-forming enzyme, and a method for producing a dipeptide are disclosed. A method for producing a dipeptide includes producing a dipeptide from a carboxy component and an amine component by using a culture of a microbe belonging to the genus Sphingobacterium and having the ability to form the dipeptide from the carboxy component and the amine component, a microbial cell separated from the culture, treated microbial cell product of the microbe or a peptide-forming enzyme derived from the microbe.

  本文揭示了编码肽形成酶的DNA和重组DNA，生产肽形成酶的方法，以及生产二肽的方法。生产二肽的方法包括使用属于拟杆菌属的微生物培养物，并具有从羧基组分和胺基组分形成二肽的能力，从培养物中分离的微生物细胞，经处理的微生物细胞产物或源自该微生物的肽形成酶，来从羧基组分和胺基组分中生产二肽。
• Method for producing tripeptides and/or peptides longer than tripeptides
  申请人：Ajinomoto Co., Inc.

  公开号：US20040219631A1

  公开（公告）日：2004-11-04

  A method is disclosed that allows the production of peptides having three or more amino acid residues easily, inexpensively and at high yield without going through a complex synthesis method. A novel enzyme that efficiently produces a peptide from bacteria belonging to the genus Empedobacter or the genus Sphingobacterium is provided. The enzyme acts on a carboxy component and an amine component to form peptides having three or more amino acid residues by acting on a carboxy component and an amine component.

  本发明揭示了一种方法，可以在不经过复杂的合成方法的情况下，轻松、廉价、高产地生产具有三个或更多氨基酸残基的肽。提供了一种从属于Empedobacter属或Sphingobacterium属的细菌中高效产生肽的新型酶。该酶通过作用于羧基组分和胺基组分来形成具有三个或更多氨基酸残基的肽。
• Novel peptide-producing enzyme, microbe producing the enzyme and method for dipeptide synthesis using them
  申请人：AJINOMOTO CO., INC.

  公开号：US20040253665A1

  公开（公告）日：2004-12-16

  The present invention relates to a novel enzyme that allows peptide to be produced easily, inexpensively and at high yield without going through a complex synthesis method. More particularly, the present invention provides a novel enzyme that catalyzes a peptide-producing reaction from a carboxy component and an amine component, a microbe that produces the enzyme, and a method for inexpensive production of peptides using this enzyme or microbe. The novel enzyme that efficiently produces peptide was discovered from a newly discovered microbe belonging to the genus Empedobacter, and a method was found that allows peptides to be produced inexpensively and easily.

  本发明涉及一种新型酶，使得可以在不经过复杂的合成方法的情况下，轻松、廉价且高产地生产肽。更具体地说，本发明提供了一种新型酶，其催化从羧基组分和胺基组分中产生肽的反应，以及一种产生该酶的微生物，以及使用该酶或微生物廉价生产肽的方法。高效生产肽的新型酶是从属于Empedobacter属的新发现微生物中发现的，并找到了一种廉价、易于生产肽的方法。
• Method for producing dipeptides
  申请人：Yokozeki Kenzo

  公开号：US20060177893A1

  公开（公告）日：2006-08-10

  The present invention provides a method for producing a dipeptide from starting materials that are available at low costs through a route industrially advantageous and simple. Dipeptides are produced from amino acid esters and amino acids by using a culture of a microbe having an ability to produce a dipeptide from an amino acid ester and an amino acid, microbial cells separated from the culture, or treated microbial cell product.

  本发明提供了一种从低成本的起始材料通过工业上有利和简单的方法生产二肽的方法。使用一种具有从氨基酸酯和氨基酸中产生二肽的能力的微生物培养物、分离自培养物的微生物细胞或经处理的微生物细胞产物来制备二肽。
• Novel peptide-forming enzyme, microbe producing the enzyme and method for producing peptide using them
  申请人：Yokozeki Kenzo

  公开号：US20050032187A1

  公开（公告）日：2005-02-10

  The present invention relates to a novel enzyme that allows peptide to be produced easily, inexpensively and at high yield without going through a complex synthesis method. More particularly, the present invention provides a novel enzyme that catalyzes a peptide-producing reaction from a carboxy component and an amine component, a microbe that produces the enzyme, and a method for inexpensive production of peptides using this enzyme or microbe. The novel enzyme that efficiently produces peptide was discovered from a newly discovered microbe belonging to the genus Empedobacter , and a method was found that allows peptides to be produced inexpensively and easily.

  本发明涉及一种新型酶，可使肽易于、廉价地高产生产，而无需经过复杂的合成方法。更具体地，本发明提供了一种催化从羧基组分和胺基组分生产肽的新型酶，一种产生该酶的微生物，以及使用该酶或微生物廉价生产肽的方法。从属于Empedobacter属的新发现微生物中发现了高效生产肽的新型酶，并找到一种可使肽廉价、易于生产的方法。