ulopterol | 36149-96-9

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: ulopterol
• 英文别名: 2',3'-Dihydroxy-dihydrosuberosin；6-(2,3-dihydroxy-3-methylbutyl)-7-methoxychromen-2-one
• CAS: 36149-96-9
• 化学式: C₁₅H₁₈O₅
• 分子量: 278.305
• InChiKey: BNLKKFPQJANWMM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  76
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  ulopterol 在 三溴化硼 作用下， 生成 6-(2',3'-dibromo-3-methyl)butyl-7-hydroxycoumarin
  参考文献：
  名称：

  Talapatra, Bani; Basak, Anjusri; Talapatra, Sunil K., Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983, vol. 22, # 5, p. 465 - 467

  摘要：

  DOI：
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 草酸 作用下， 生成 ulopterol
  参考文献：
  名称：

  King et al., Journal of the Chemical Society, 1954, p. 1392,1395

  摘要：

  DOI：

文献信息

• [EN] PHARMACEUTICAL COMPOSITION COMPRISING THE PLANT COLEONEMA<br/>[FR] COMPOSITION PHARMACEUTIQUE COMPORTANT LA PLANTE COLEONEMA
  申请人：GROENEWALD JOHANNES GERHARDUS

  公开号：WO2005105124A1

  公开（公告）日：2005-11-10

  The plant material or extract of the plant may be from C. album, C. nubigenum, C. juniperinum, C. calycinum, C. aspalathoides, C. pulchellum, C. virgatum and C. pulchrum. The pharmaceutical composition is particularly suitable for use as an immune stimulant, an antibacterial agent, an antifungal agent, an antiviral agent (in particular for treatment of HIV), an anti-inflammatory agent or an anti-oxidant. The composition may include at least one of the following compounds: 1, 2', 3'-dihydroxydihydrosuberosin (2H-1-benzopyran-2-one, 6-(2,3-dihydroxy-3-methylbutyl)-7-methoxy, 2H-1-benzopyran-2-one, 6-(3,3-dimethyloxiranyl)-7-methoxy); 5,5'-(tetrahydro-1H,3H-furo[3,4c]-furan-1,4-diyl)bis-[1S-(1 α.,3a.α,4.β.,6a)-1,3 benzodioxole; 6-(2,3-dihydroxy-3-methylbutyl)-7-methoxy-2H-1-benzopyran-2-one; 6-(3,3-dihydroxy-3-methylbutyl)-7-methoxy-2H­1-benzopyran-2-one; 7-methoxy-6-(3,3-methyl-2butenyl)- 2H-1-benzopyran-2-one; 6-[(3,3-dimethyloxiranyl)methyl]-7-metoxy-2H-1-benzopyran-2-one; 6-(2 ,3-dihydroxy-3-methylbutyl)-7-methoxy-2H-1-benzopyran-2-one; 6-(3,3-dimethyloxiranyl) methyl]-7-metoxy-2H-1-benzopyran-2-one; Esculetin; 3,4-dihydro-5-hydroxy-2,2,8-trimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-6-one; 2-(1-hydroxy-1-methylethyl)-2,3-dihydrofuro[3,2-g] chromen-7-one; 7-methoxy-6-(3-methyl-2-oxobutyl)- 2H-1-benzopyran-2-one; 2,2-dimethyl-pyrano(3,2-c)(1)benzopyran-5-one; 9,10-dihydro-9-hydroxy-8,8-dimethyl-2H,8H-Benzo[1,2-b:3,4-b']dipyran-2-one; n-hexadecanoic acid; 4-(4-hydroxyphenyl)- 2-butanone; 8-[ß-D-glucopyranosyloxy)-1-methylethyl]-8,9-dihydro-2H-furo[2,3-h]-1-benzopyran-2-one; 2-isopropenyl-2,3-dihydrofuro[3,2-g] chromen-7-one; 2-(3,4-dihydroxyphenyl)-3-(ß.-D-galactopyranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one; Vitamin E; and pharmaceutically acceptable derivatives or salts thereof. A method of treating a patient using plant material or an extract as described above is also described, as is the compound 1, 2', 3'-dihydroxydihydrosuberosin and pharmaceutically acceptable derivatives or salts thereof for treating a patient.
• King et al., Journal of the Chemical Society, 1954, p. 1392,1395
  作者：King et al.

  DOI：——

  日期：——
• Talapatra, Bani; Basak, Anjusri; Talapatra, Sunil K., Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983, vol. 22, # 5, p. 465 - 467
  作者：Talapatra, Bani、Basak, Anjusri、Talapatra, Sunil K.

  DOI：——

  日期：——