2,3-bis-benzoylamino-succinic acid | 101914-12-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2,3-bis-benzoylamino-succinic acid
• 英文别名: 2,3-Bis-benzoylamino-bernsteinsaeure；2,3-Dibenzamidobutanedioic acid
• CAS: 101914-12-9；780769-20-2
• 化学式: C₁₈H₁₆N₂O₆
• 分子量: 356.335
• InChiKey: WTVMWQGJGNVCPS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  26
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  133
• 氢给体数：
  4
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  2,3-bis-benzoylamino-succinic acid 在 氯化亚砜 作用下， 反应 2.0h， 以78%的产率得到Hippuroflavin
  参考文献：
  名称：

  [EN] NEW HETEROCYCLIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYES AND PIGMENTS
  [FR] NOUVEAUX COMPOSES HETEROCYCLIQUES, PROCEDE DE PREPARATION DE CES COMPOSES ET LEUR UTILISATION EN TANT QUE COLORANTS ET PIGMENTS

  摘要：

  化合物的公式（I），其中R1是氢，羟基，卤素，硝基，氰基，氨基，羧基，羧酸酯，磺基，磺酸酯，羧酰胺，磺酰胺，烷基硫基，芳基硫基，烷氧基或芳氧基，R'1是氢，羟基，卤素，硝基，氰基，氨基，羧基，羧酸酯，磺基，磺酸酯，羧酰胺，磺酰胺，烷基硫基，芳基硫基，烷氧基或芳氧基，X是-O-，-S-，-NH-或-N（烷基）-，X'是-O-，-S-，-NH-或-N（烷基）-，Y是氢或羧酸酯，Y'是氢或羧酸酯，Z是=C-或=N-，Z'是=C-或=N-，x是0或1，当Z是=N-时，x是0，y是0或1，当Z'是=N-时，y是0，A是公式（II），（III），（IV），（V）或（VI）的共轭连接桥，其中n为0，1，2或3，m为0，1，2或3，B为苯环，T为=C（R3）-或=N-，其中R3为氢，C1-C12烷基或CN，W为未取代或取代的烷基，卤素，羟基，烷氧基，烷硫基或氨基的杂环，或线性或多缩合芳香基团，G为-CH=或-N=，R2为氢，烷基，卤素，羟基，烷氧基，烷硫基或氨基，它们的制备以及它们在生产有色塑料或聚合物颜色颗粒中的应用。

  公开号：

  WO2004089941A1
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 生成 2,3-bis-benzoylamino-succinic acid
  参考文献：
  名称：

  Farchy; Tafel, Chemische Berichte, 1893, vol. 26, p. 1989

  摘要：

  DOI：

文献信息

• New heterocyclic compounds, a process for their preparation and their use as dyes and pigments
  申请人：Adam Jean-Marie

  公开号：US20060124014A1

  公开（公告）日：2006-06-15

  Compounds of formula (I) wherein R 1 is hydrogen, hydroxy, halogen, nitro, cyano, amino, carboxy, carboxylic ester, sulfo, sulfonic ester, carboxylic amide, sulfonic amide, alkylthio, arylthio, alkoxy or aryloxy, R′ 1 is hydrogen, hydroxy, halogen, nitro, cyano, amino, carboxy, carboxylic ester, sulfo, sulfonic ester, carboxylic amide, sulfonic amide, alkylthio, arylthio, alkoxy or aryloxy, X is —O—, —S—, —NH— or —N(alkyl)-, X′ is —O—, —S—, —NH— or —N(alkyl)-, Y is hydrogen or carboxylic ester, Y′ is hydrogen or carboxylic ester, Z is ═C— or ═N—, Z′ is ═C— or ═N—, x is 0 or 1, when Z is ═N—, then x is 0, y is 0 or 1, when Z′ is ═N—, then y is 0, A is a conjugated linking bridge of the formulae (II), (III), (IV), (V), or (VI), wherein n is 0, 1, 2 or 3, m is 0, 1, 2 or 3, B is a phenyl ring, T is ═C(R 3 )— or ═N—, wherein R 3 is hydrogen, C 1 -C 12 alkyl or CN, W is a heterocyclic, or linear or polycondensed aromatic group which is unsubstituted or substituted by alkyl, halogen, hydroxy, alkoxy, alkylthio or amino, G is —CH═ or —N═, and R 2 is hydrogen, alkyl, halogen, hydroxy, alkoxy, alkylthio or amino, their preparation and their use in the production of coloured plastics or polymeric color particles.

  式(I)化合物 其中 R 1 是氢、羟基、卤素、硝基、氰基、氨基、羧基、羧酸酯、磺酸酯、磺酸酰胺、羧酸酰胺、磺酸酰胺、烷硫基、芳硫基、烷氧基或芳氧基， R′ 1 是氢、羟基、卤素、硝基、氰基、氨基、羧基、羧酸酯、磺酸、磺酸酯、羧酸酰胺、磺酸酰胺、烷硫基、芳硫基、烷氧基或芳氧基，X 是-O-、-S-、-NH-或-N（烷基）-，X′ 是-O-、-S-、-NH-或-N（烷基）-，Y 是氢或羧酸酯、Y′是氢或羧酸酯，Z是═C-或═N-，Z′是═C-或═N-，x是0或1，当Z是═N-时，则x是0，y是0或1，当Z′是═N-、则 y 是 0，A 是式 (II)、(III)、(IV)、(V) 或 (VI) 的共轭连接桥，其中 n 是 0、1、2 或 3，m 是 0、1、2 或 3，B 是一个苯基环，T 是 ═C(R 3 )-或═N-，其中 R 3 是氢、C 1 -C 12 烷基或 CN，W 是未被取代或被烷基、卤素、羟基、烷氧基、烷硫基或氨基取代的杂环基团或线性或多缩合芳香基团，G 是 -CH═ 或 -N═，以及 R 2 是氢、烷基、卤素、羟基、烷氧基、烷硫基或氨基。
• Kuhn; Zumstein, Chemische Berichte, 1925, vol. 58, p. 1431
  作者：Kuhn、Zumstein

  DOI：——

  日期：——
• NEW HETEROCYCLIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYES AND PIGMENTS
  申请人：Ciba Specialty Chemicals Holding Inc.

  公开号：EP1603902A1

  公开（公告）日：2005-12-14
• New compounds, a process for their preparation and their use as dyes and pigments
  申请人：Adam Jean-Marie

  公开号：US20060258784A1

  公开（公告）日：2006-11-16

  Compounds of formula (1) wherein R 1 is hydrogen, hydroxy, halogen, nitro, cyano, amino, carboxy, carboxylic ester, sulfo, sulfonic ester, carboxylic amide, sulfonic amide, alkylthio, arylthio, alkoxy or aryloxy, R′ 1 is hydrogen, hydroxy, halogen, nitro, cyano, amino, carboxy, carboxylic ester, sulfo, sulfonic ester, carboxylic amide, sulfonic amide, alkylthio, arylthio, alkoxy or aryloxy, X is —O—, —S—, —NH— or —N(alkyl)—, X′ is —O—, —S—, —NH— or —N(alkyl)—, Y is hydrogen or carboxylic ester, Y′ is hydrogen or carboxylic ester, Z is ═C— or ═N—, Z′ is ═C— or ═N—, x is 0 or 1, when Z is ═N—, then x is 0, y is 0 or 1, when Z′ is ═N—, then y is 0, A is a conjugated linking bridge of the formula wherein n is 0, 1, 2 or 3, m is 0, 1, 2 or 3, B is a phenyl ring, T is ═C(R 3 )— or ═N—, wherein R 3 is hydrogen, C 1 -C 12 alkyl or CN, W is a heterocyclic, or linear or polycondensed aromatic group which is unsubstituted or substituted by alkyl, halogen, hydroxy, alkoxy, alkylthio or amino, G is —CH═ or —N═, and R 2 is hydrogen, alkyl, halogen, hydroxy, alkoxy, alkylthio or amino, their preparation and their use in the production of coloured plastics or polymeric colour particles.
• [EN] NEW HETEROCYCLIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYES AND PIGMENTS<br/>[FR] NOUVEAUX COMPOSES HETEROCYCLIQUES, PROCEDE DE PREPARATION DE CES COMPOSES ET LEUR UTILISATION EN TANT QUE COLORANTS ET PIGMENTS
  申请人：CIBA SC HOLDING AG

  公开号：WO2004089941A1

  公开（公告）日：2004-10-21

  Compounds of formula (I) wherein R1 is hydrogen, hydroxy, halogen, nitro, cyano, amino, carboxy, carboxylic ester, sulfo, sulfonic ester, carboxylic amide, sulfonic amide, alkylthio, arylthio, alkoxy or aryloxy, R'1 is hydrogen, hydroxy, halogen, nitro, cyano, amino, carboxy, carboxylic ester, sulfo, sulfonic ester, carboxylic amide, sulfonic arnide, alkylthio, arylthio, alkoxy or aryloxy, X is -O-, -S-, -NH- or -N(alkyl)-, X' is -0-, -S-, -NH- or -N(alkyl)-, Y is hydrogen or carboxylic ester, Y' is hydrogen or carboxylic ester, Z is =C- or =N-, Z' is =C- or =N-, x is 0 or 1, when Z is =N-, then x is 0, y is 0 or 1, when Z' is =N-, then y is 0, A is a conjugated linking bridge of the formulae (II), (III), (IV), (V), or (VI), wherein n is 0, 1, 2 or 3, m is 0, 1, 2 or 3, B is a phenyl ring, T is =C(R3)- or =N-, wherein R3 is hydrogen, C1-C12alkyl or CN, W is a heterocyclic, or linear or polycondensed aromatic group which is unsubstituted or substituted by alkyl, halogen, hydroxy, alkoxy, alkylthio or amino, G is -CH= or -N=, and R2 is hydrogen, alkyl, halogen, hydroxy, alkoxy, alkylthio or amino, their preparation and their use in the production of coloured plastics or polymeric color particles.

  化合物的公式（I），其中R1是氢，羟基，卤素，硝基，氰基，氨基，羧基，羧酸酯，磺基，磺酸酯，羧酰胺，磺酰胺，烷基硫基，芳基硫基，烷氧基或芳氧基，R'1是氢，羟基，卤素，硝基，氰基，氨基，羧基，羧酸酯，磺基，磺酸酯，羧酰胺，磺酰胺，烷基硫基，芳基硫基，烷氧基或芳氧基，X是-O-，-S-，-NH-或-N（烷基）-，X'是-O-，-S-，-NH-或-N（烷基）-，Y是氢或羧酸酯，Y'是氢或羧酸酯，Z是=C-或=N-，Z'是=C-或=N-，x是0或1，当Z是=N-时，x是0，y是0或1，当Z'是=N-时，y是0，A是公式（II），（III），（IV），（V）或（VI）的共轭连接桥，其中n为0，1，2或3，m为0，1，2或3，B为苯环，T为=C（R3）-或=N-，其中R3为氢，C1-C12烷基或CN，W为未取代或取代的烷基，卤素，羟基，烷氧基，烷硫基或氨基的杂环，或线性或多缩合芳香基团，G为-CH=或-N=，R2为氢，烷基，卤素，羟基，烷氧基，烷硫基或氨基，它们的制备以及它们在生产有色塑料或聚合物颜色颗粒中的应用。