申请人:THE KITASATO INSTITUTE
公开号:US10307356B2
公开(公告)日:2019-06-04
Provided are: a method for producing a mycrosporine-like amino acid (MAA) that includes a step in which microbes are cultivated that produce MAA on the outside of bacterial cells, a step in which the bacterial cells and extracellular culture fluid are separated, and a step in which the MAA is recovered from the extracellular culture fluid; an MAA indicated by formula (1), an MAA produced using this method, or an ultraviolet-absorbing composition including the MAA indicated by formula (1); and a composition including the MAA produced using this method or the MAA indicated by formula (1), for preventing at least one symptom or disease selected from a group comprising acute skin reactions, aging of the skin, and skin cancer.
提供了一种生产霉菌孢子样氨基酸(MAA)的方法,该方法包括培养在细菌细胞外产生 MAA 的微生物的步骤,分离细菌细胞和细胞外培养液的步骤,以及从细胞外培养液中回收 MAA 的步骤;式(1)所示的 MAA、用该方法生产的 MAA 或包括式(1)所示的 MAA 的紫外线吸收组合物;以及包括用该方法生产的 MAA 或式(1)所示的 MAA 的组合物,用于预防至少一种选自急性皮肤反应、皮肤老化和皮肤癌的症状或疾病。