(3,4,5,6-Tetrahydro-2H-[2,3']bipyridinyl-1-yl)acetic acid hydrazide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (3,4,5,6-Tetrahydro-2H-[2,3']bipyridinyl-1-yl)acetic acid hydrazide
• 英文别名: 2-(2-pyridin-3-ylpiperidin-1-yl)acetohydrazide
• 化学式: C₁₂H₁₈N₄O
• 分子量: 234.301
• InChiKey: AXCHOLYWQTZDPB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.4
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  71.2
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  (3,4,5,6-Tetrahydro-2H-[2,3']bipyridinyl-1-yl)acetic acid hydrazide 、 5-溴水杨醛 以 乙醇 为溶剂， 反应 1.0h， 以86%的产率得到
  参考文献：
  名称：

  Synthesis of hydrazones of anabasinylacetic acid and structure of its isopropylidenehydrazone

  摘要：

  Some hydrazones based on N-anabasinylacetic acid hydrazide have been synthesized. Structure of N'-isopropylidenehydrazone of N-anabasinylacetic acid has been studied by X-ray diffraction.

  DOI：

  10.1134/s1070363214080180
• 作为产物：
  描述：

  methyl 2-(2-pyridin-3-ylpiperidin-1-yl)acetate 在 一水合肼 作用下， 以 水 为溶剂， 以57%的产率得到(3,4,5,6-Tetrahydro-2H-[2,3']bipyridinyl-1-yl)acetic acid hydrazide
  参考文献：
  名称：

  Synthesis of hydrazones of anabasinylacetic acid and structure of its isopropylidenehydrazone

  摘要：

  Some hydrazones based on N-anabasinylacetic acid hydrazide have been synthesized. Structure of N'-isopropylidenehydrazone of N-anabasinylacetic acid has been studied by X-ray diffraction.

  DOI：

  10.1134/s1070363214080180

文献信息

• Synthesis of hydrazones of anabasinylacetic acid and structure of its isopropylidenehydrazone
  作者：I. V. Kulakov、O. A. Nurkenov、Zh. B. Satpaeva、K. M. Turdybekov

  DOI：10.1134/s1070363214080180

  日期：2014.8

  Some hydrazones based on N-anabasinylacetic acid hydrazide have been synthesized. Structure of N'-isopropylidenehydrazone of N-anabasinylacetic acid has been studied by X-ray diffraction.