7-(3,4-dimethylphenyl)-10,10-dimethyl-10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione | 1309477-37-9

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: 7-(3,4-dimethylphenyl)-10,10-dimethyl-10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione
• 英文别名: 7-(3,4-dimethylphenyl)-10,10-dimethyl-9,11-dihydro-7H-chromeno[3,2-c]chromene-6,8-dione
• CAS: 1309477-37-9
• 化学式: C₂₆H₂₄O₄
• 分子量: 400.474
• InChiKey: YWOJFLYQUHLLOH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  30
• 可旋转键数：
  1
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  4-羟基香豆素 、 3,4-二甲基苯甲醛 、 5,5-二甲基-1,3-环己二酮 在 1,3-dimethyl-2-oxo-1,3-bis(4-sulfobutyl)imidazolidine-1,3-diium hydrogen sulfate 作用下， 以 水 为溶剂， 反应 4.0h， 以90%的产率得到7-(3,4-dimethylphenyl)-10,10-dimethyl-10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione
  参考文献：
  名称：

  A novel sulfonic acid functionalized ionic liquid catalyzed multicomponent synthesis of 10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione derivatives in water

  摘要：

  Three-component reactions of 4-hydroxycoumarin, aldehydes, and cyclic 1,3-dicarbonyl compounds were prompted by novel sulfonic acid functionalized ionic liquids 1,3-dimethyl-2-oxo-1,3-bis(4-sulfobutyl)imidazolidine-1,3-diium hydrogen sulfate ([DMDBSI]center dot 2HSO(4)) in water at reflux temperature to provide a novel series of 10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione derivatives for the first time in high yields. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.03.059

文献信息

• A novel sulfonic acid functionalized ionic liquid catalyzed multicomponent synthesis of 10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione derivatives in water
  作者：Zhiwei Chen、Qiang Zhu、Weike Su

  DOI：10.1016/j.tetlet.2011.03.059

  日期：2011.5

  Three-component reactions of 4-hydroxycoumarin, aldehydes, and cyclic 1,3-dicarbonyl compounds were prompted by novel sulfonic acid functionalized ionic liquids 1,3-dimethyl-2-oxo-1,3-bis(4-sulfobutyl)imidazolidine-1,3-diium hydrogen sulfate ([DMDBSI]center dot 2HSO(4)) in water at reflux temperature to provide a novel series of 10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione derivatives for the first time in high yields. (C) 2011 Elsevier Ltd. All rights reserved.