Tridecapentain-(3,5,7,9,11)-diol-(1,2) | 1771-89-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Tridecapentain-(3,5,7,9,11)-diol-(1,2)
• 英文别名: 1,2-Dihydroxy-tridecapentain-(3,5,7,9,11)；trideca-3,5,7,9,11-pentayne-1,2-diol
• CAS: 1771-89-7
• 化学式: C₁₃H₈O₂
• 分子量: 196.205
• InChiKey: KCSPFTFVNJTPDP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  Tridecapentain-(3,5,7,9,11)-diol-(1,2) 在 sodium periodate 作用下， 生成 dodeca-2,4,6,8,10-pentaynal
  参考文献：
  名称：

  Bohlmann,F.; Moench,H., Chemische Berichte, 1967, vol. 100, p. 1944 - 1948

  摘要：

  DOI：

文献信息

• マラリヤ治療剤
  申请人：飛永 精照

  公开号：JP2008214260A

  公开（公告）日：2008-09-18

  【課題】コセンダングサ中に含まれ、耐性を有するマラリヤに対しても有効に作用する化合物を単離し、その化学構造を解明して、マラリヤ治療に対して優れた効果を示す治療薬を提供する。【解決手段】一般式（式中のＲは水素原子又はグルコース基である）で表わされる（Ｒ）‐１，２‐ジヒドロキシトリデカ‐３，５，７，９，１１‐ペンタイン又はその配糖体を有効成分としてなるマラリヤ治療剤とする。【選択図】なし

  该化合物的化学结构已被阐明，从而提供了一种治疗疟疾效果极佳的治疗剂。 (R)-1,2-二羟基十三烷-3,5,7,9,11-五碱由通式代表（式中 R 为氢原子或葡萄糖基）或其糖苷作为有效的 效成分是一种疟疾治疗剂。 选择图表] 无。
• Immunologically active phyto-mixture and its use in the prevention and in a method for treatment of efflorescences
  申请人：Wilmanowicz Renate

  公开号：US10806765B2

  公开（公告）日：2020-10-20

  The present invention relates to an immunologically active phyto-mixture comprising at least one plant extract selected from the family (a) Asteraceae, (b) Verbenaceae, and/or (c) Burseraceae, preferably at least one plant extract from the genus (a) Bidens, (b) Stachytarpheta, and/or (c) Bursera. Particularly preferred species include (a) Bidens alba, Bidens pilosa, (b) Stachytarpheta jamaicensis, Stachytarpheta cayennensis, Stachytarpheta indica, and/or (c) Bursera simaruba, Bursera microphylla, Bursera glabrifolia. The phyto-mixture optionally comprises (d) at least one further biologically active plant extract, such as Aloe vera and/or Stemodia maritima. The afore-mentioned phyto-mixture according to the invention exhibits good antimicrobial and anti-inflammatory efficiency and is particularly suitable for prevention and treatment of efflorescences. Therefore, the present invention also relates to a preparation for oral and topical administration for prevention and treatment of efflorescences of the skin and the mucous membrane.

  本发明涉及一种具有免疫活性的植物混合物，该混合物包含至少一种选自(a)菊科、(b)马鞭草科和/或(c)Burseraceae的植物提取物，优选至少一种选自(a)Bidens属、(b)Stachytarpheta属和/或(c)Bursera属的植物提取物。特别优选的物种包括 (a) Bidens alba, Bidens pilosa, (b) Stachytarpheta jamaicensis, Stachytarpheta cayennensis, Stachytarpheta indica, 和/或 (c) Bursera simaruba, Bursera microphylla, Bursera glabrifolia。植物混合物可选包括(d) 至少一种生物活性植物提取物，如芦荟和/或 Stemodia maritima。根据本发明，上述植物混合物具有良好的抗菌和消炎功效，尤其适用于预防和治疗鳞屑病。因此，本发明还涉及一种口服和外用制剂，用于预防和治疗皮肤和粘膜的鳞状上皮细胞增生症。
• Bohlmann,F. et al., Chemische Berichte, 1965, vol. 98, p. 1228 - 1232
  作者：Bohlmann,F. et al.

  DOI：——

  日期：——
• IMMUNOLOGISCH AKTIVES PHYTO-GEMISCH UND SEINE ANWENDUNG BEI DER PRÄVENTION UND IN EINEM VERFAHREN ZUR BEHANDLUNG VON EFFLORESZENZEN
  申请人：Wilmanowicz, Renate

  公开号：EP3256142B1

  公开（公告）日：2019-11-06
• IMMUNOLOGICALLY ACTIVE PHYTO-MIXTURE AND ITS USE IN THE PREVENTION AND IN A METHOD FOR TREATMENT OF EFFLORESCENCES
  申请人：Wilmanowicz Renate

  公开号：US20180036360A1

  公开（公告）日：2018-02-08

  The present invention relates to an immunologically active phyto-mixture comprising at least one plant extract selected from the family a) Asteraceae, b) Verbenaceae, and/or c) Burseraceae, preferably at least one plant extract from the genus a) Bidens , b) Stachytarpheta , and/or c) Bursera . Particularly preferred species include a) Bidens alba, Bidens pilosa , b) Stachytarpheta jamaicensis, Stachytarpheta cayennensis, Stachytarpheta indica , and/or c) Bursera simaruba, Bursera microphylla, Bursera glabrifolia . The phyto-mixture optionally comprises d) at least one further biologically active plant extract, such as Aloe vera and/or Stemodia maritima . The afore-mentioned phyto-mixture according to the invention exhibits good antimicrobial and anti-inflammatory efficiency and is particularly suitable for prevention and treatment of efflorescences. Therefore, the present invention also relates to a preparation for oral and topical administration for prevention and treatment of efflorescences of the skin and the mucous membrane.