2-Benzyl-2,6,3',4'-tetrahydroxycumaran-3-on | 89984-19-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 橙酮类黄酮
• 英文名称: 2-Benzyl-2,6,3',4'-tetrahydroxycumaran-3-on
• 英文别名: 2-Benzyl-2,6,3',4'-tetrahydroxycumaranon-(3)；2,6,3',4'-Tetrahydroxy-2-benzylcoumaranone；2-[(3,4-dihydroxyphenyl)methyl]-2,6-dihydroxy-1-benzofuran-3-one
• CAS: 89984-19-0
• 化学式: C₁₅H₁₂O₆
• 分子量: 288.257
• InChiKey: LCHNFNNYVOUXRN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  107
• 氢给体数：
  4
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  2-Benzyl-2,6,3',4'-tetrahydroxycumaran-3-on 、 乙酸酐 在 吡啶 作用下， 以12 mg的产率得到(+/-)-2-benzyl-2,3',4',6-tetra-acetoxybenzofuran-3(2H)-one
  参考文献：
  名称：

  来自赞比西亚黄尾蚴的α-羟基二氢查耳酮和相关的1,3-二芳基丙-2-酮

  摘要：

  摘要 除了一些先前描述的 7,8-二氧基-异黄酮和 2-苄基苯并[b]呋喃-3 (2H)-ones 之外，赞比亚黄尾草的心材已被证明含有 7,8,3'-trihydroxy-4' -甲氧基异黄酮。这些伴随着新的 α,3,4,4'-四羟基-2'-甲氧基二氢查耳酮及其 3-脱氧类似物，后者可能是独特的 1-羟基-3-(4-羟基苯基)-1-(4-羟基-2-甲氧基苯基)丙-2-酮及其1-脱氧类似物。这种可能的生物合成关系通过适当的 α-羟基二氢查耳酮在体外轻松转化为不同的 1,3-二芳基丙-2-酮来证明。

  DOI：

  10.1016/0031-9422(88)80154-7

文献信息

• RHUS VERNICIFLUA STOKES EXTRACT HAVING INCREASED CONTENT OF ACTIVE FLAVONOID COMPOUND AND METHOD FOR PREPARING SAME
  申请人：AZI Company Ltd.

  公开号：EP2604274B1

  公开（公告）日：2016-07-13
• Rhus Verniciflua Stokes Extract Having Increased Content Of Active Flavonoid Compound And Method For Preparing Same
  申请人：Park Sang-Jae

  公开号：US20120283322A1

  公开（公告）日：2012-11-08

  The present invention relates to Rhus verniciflua Stokes extract having an increased content of an active flavonoid compound through a gas bubbling treatment, a method for preparing the Rhus verniciflua Stokes extract, and a method for converting fustin into fisetin through the gas bubbling treatment of a solution containing fustin. The method for preparing the Rhus verniciflua Stokes extract of the present invention can convert the conventional Rhus verniciflua Stokes extract having high content of fustin and low content of fisetin into a Rhus verniciflua Stokes extract having high content of fisetin. Therefore, the Rhus verniciflua Stokes extract of the present invention can be commercialized into natural anticancer agents, anticancer and cancer prevention food products, and health functional foods due to the excellent bioactivity thereof, and promote the development of relevant industries through the high added-value of Rhus verniciflua Stokes. In addition, the method for converting fustin into fisetin can be applied to other natural substances and be used as a method for enhancing the functionality thereof by increasing the content of a high active flavonoid, thereby becoming an enabling technology that can lead high-functionalization of natural substances.
• Method of Converting Fustin to Fisetin
  申请人：AZI COMPANY LTD.

  公开号：US20140031567A1

  公开（公告）日：2014-01-30

  The present invention relates to a method for converting fustin into fisetin through the gas bubbling treatment of a solution containing fustin. Rhus verniciflua Stokes extracts having high content of Fisetin may be used as anticancer agents, anticancer and cancer prevention food products, and health functional foods due to the excellent bioactivity thereof.
• US8551537B2
  申请人：——

  公开号：US8551537B2

  公开（公告）日：2013-10-08
• US8859014B2
  申请人：——

  公开号：US8859014B2

  公开（公告）日：2014-10-14