Versatile and Expeditious Synthesis of Aurones via Au<sup>I</sup>-Catalyzed Cyclization
作者:Hassina Harkat、Aurélien Blanc、Jean-Marc Weibel、Patrick Pale
DOI:10.1021/jo702197b
日期:2008.2.1
Aurones are conveniently formed in a three-step procedure including a goldI-catalyzed cyclization of 2-(1-hydroxyprop-2-ynyl)phenols as a highly regio- and stereoselective key step. A wide diversity of derivatives can be obtained starting from substituted salicylaldehydes. Synthesis of natural 4,6,3‘,4‘-tetramethoxyaurone and structure revision of two natural products (dalmaisione D and 4‘-chloroaurone)
Aurones: Unexplored Visible‐Light Photoswitches for Aqueous Medium
作者:Daria V. Berdnikova
DOI:10.1002/chem.202304237
日期:2024.4.5
Aurone derivatives have been introduced for the first time as a novel class of visible-light photoswitches in aqueous medium possessing good quantum yields, high conversions in photostationary states and remarkably long (up to 7 years) lifetimes of the photoisomers. Moreover, the aurone scaffold can be easily modified with functional substituents without affecting its robust photochemical performance
The easily available and efficient catalyst containing a benzimidazolium ligand and PdCl2(PPh3)(2) demonstrated excellent catalytic activity to construct the flavones and aurones, respectively. This reaction can be operated under mild conditions, affording the desired products in moderate to good yields. This protocol was used to prepare the flavones and aurones by a slight modification of amines. (C) 2013 Elsevier Ltd. All rights reserved.