2-(Hydroxymethyl)-6-(1-hydroxytrideca-5,7,9,11-tetrayn-2-yloxy)oxane-3,4,5-triol

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-(Hydroxymethyl)-6-(1-hydroxytrideca-5,7,9,11-tetrayn-2-yloxy)oxane-3,4,5-triol
• 化学式: C₁₉H₂₂O₇
• 分子量: 362.4
• InChiKey: LIVZHGSTYIVZNV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  26
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  120
• 氢给体数：
  5
• 氢受体数：
  7

文献信息

• Butanol extract of Bidens pilosa
  申请人：Yang Wen-Chin

  公开号：US20070053998A1

  公开（公告）日：2007-03-08

  A compound of the formula: wherein R 1 is H, alkyl, aryl, or cyclyl; R 2 is pyranose; R 3 is H or alkyl; m is 2, 3, 4, 5, or 6; n is 0, 1, 2, or 3; o is 0, 1, 2, 3, 4; and p is 1, 2, 3, or 4. Also disclosed is use of the compound to inhibit Th1 differentiation, promote Th2 differentiation, and treat certain disorders.
• Polyacetylenic Compounds
  申请人：Yang Wen-Chin

  公开号：US20080193568A1

  公开（公告）日：2008-08-14

  This invention relates to a method of treating type II diabetes with a polyacetylenic compound of the following formula: in which R 1 is H, C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, C 3 -C 20 cycloalkyl, C 3 -C 20 cycloalkenyl, C 1 -C 20 heterocycloalkyl, C 1 -C 20 heterocycloalkenyl, aryl, or heteroaryl; R 2 is H or a monosaccharide residue; R 3 is H or C 1 -C 10 alkyl; m is 2, 3, or 4; n is 0, 1, 2, or 3; o is 0, 1, 2, 3, or 4; and p is 1, 2, 3, or 4.
• BUTANOL EXTRACT OF BIDENS PILOSA
  申请人：Yang Wen-Chin

  公开号：US20090062216A1

  公开（公告）日：2009-03-05

  A method of treating a Th1-mediated disorder includes administering to a subject in need of the treatment an effective amount of a compound of the formula I: wherein R 1 is H, alkyl, aryl, or cyclyl; R 2 is pyranose; R 3 is H or alkyl; m is 2, 3, 4, 5, or 6; n is 0, 1, 2, or 3; o is 0, 1, 2, 3, 4; p is 1, 2, 3, or 4; and the Th1-mediated disorder is non-obese diabetes, Crohn's colitis, autoimmune hemolytic anemia, rheumatoid arthritis, autoimmune encephalitis, multiple sclerosis, or autoimmune myocarditis. Also disclosed is a pharmaceutical composition including a compound of formula I above and a pharmaceutically acceptable carrier.
• BIDENS PILOSA AND POLYACETYLENIC COMPOUNDS FOR PREVENTION AND TREATMENT OF COCCIDIOSIS
  申请人：ACADEMIA SINICA

  公开号：US20140308378A1

  公开（公告）日：2014-10-16

  A composition for use in prevention, inhibition and/or treatment of coccidiosis in an animal is disclosed. The composition comprises an effective amount of Bidens pilosa, an active constituent thereof, or an active compound isolated therefrom. In another aspect, a composition for use in preventing and/or treating coccidiosis, and/or enhancing growth in an animal is disclosed, the composition comprising an animal feed and an effective amount of Bidens pilosa, or an isolated active constituent comprising a polyacetylenic compound.
• BIDENS PILOSA AND POLYACETYLENIC COMPOUNDS FOR PREVENTION AND TREATMENT OF COCCIDIOSIS
  申请人：ACADEMIA SINICA

  公开号：US20150272975A1

  公开（公告）日：2015-10-01

  A composition for use in prevention, inhibition and/or treatment of coccidiosis in an animal is disclosed. The composition comprises an effective amount of Bidens pilosa , an active constituent thereof, or an active compound isolated therefrom.