N-(6,8-dihydroxy-2-phenyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-7-yl)acetamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡喃二恶英
• 英文名称: N-(6,8-dihydroxy-2-phenyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-7-yl)acetamide
• 化学式: C₁₅H₁₉NO₆
• 分子量: 309.319
• InChiKey: OIXDAEIOQFFRMF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.7
• 重原子数：
  22
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  97.2
• 氢给体数：
  3
• 氢受体数：
  6

文献信息

• [EN] SYNTHESIS OF 6-AZIDO-6-DEOXY-2-N-ACETYL-HEXOSAMINE-NUCLEOSIDE DIPHOSPHATE<br/>[FR] SYNTHÈSE DE 6-AZIDO-6-DÉSOXY-2-N-ACÉTYL-HEXOSAMINE-NUCLÉOSIDE DIPHOSPHATE
  申请人：SYNAFFIX BV

  公开号：WO2021015622A1

  公开（公告）日：2021-01-28

  The current invention concerns methods for the synthesis of 6-azido-6-deoxy-2-N-acetyl-monosaccharide-nucleoside diphosphate, in particular 6-azido-6-deoxy-2-N-acetyl-D- galactosamine-nucleoside diphosphate or 6-azido-6-deoxy-2-N-acetyl-D-glucosamine-nucleoside diphosphate. The synthesis method according to the invention is characterized by being highly efficient and high yielding. Also part of the present invention are key intermediates of this process.

  当前的发明涉及合成6-叠氮-6-去氧-2-N-乙酰-单糖核苷二磷酸的方法，特别是6-叠氮-6-去氧-2-N-乙酰-D-半乳糖核苷二磷酸或6-叠氮-6-去氧-2-N-乙酰-D-葡萄糖胺核苷二磷酸。根据本发明的合成方法具有高效率和高产率的特点。此外，本发明还涉及该过程的关键中间体。
• PROCESS FOR THE SYNTHESIS OF L-FUCOSYL DI- OR OLIGO-SACCHARIDES AND NOVEL 2,3,4 TRIBENZYL-FUCOSYL DERIVATIVES INTERMEDIATES THEREOF
  申请人：Salsini Liana

  公开号：US20110245488A1

  公开（公告）日：2011-10-06

  The present invention relates to a process for the synthesis of L-fucosyl di- or oligosaccharides and their novel 2,3,4-tri-O-benzyl-fucosyl synthetic intermediates derivatives of easy crystallization. In particular the present invention relates to a process applicable to industrial scale for the synthesis of 2′O-fucosyl lactose.

  本发明涉及一种合成L-岩藻糖二糖或寡糖的过程，以及易于结晶的新型2,3,4-三-O-苄基-岩藻糖合成中间体衍生物。特别是，本发明涉及一种适用于工业规模的合成2'O-岩藻糖乳糖的过程。