3-Methyl-nonandisaeure | 76078-85-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 3-Methyl-nonandisaeure
• 英文别名: '2'-Methyl-nonandisaeure；3-methyl-nonanedioic acid；3-Methylazelaic acid；3-methylnonanedioic acid
• CAS: 76078-85-8
• 化学式: C₁₀H₁₈O₄
• 分子量: 202.251
• InChiKey: PLOUQIGEQKCKHG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  14
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  3-Methyl-nonandisaeure 在 dethiobiotin synthase 、 E_.C_. 6.6.6.6 、 二叔丁基硅烷 5’-三磷酸腺苷 作用下， 以 水 为溶剂， 生成 7-Methyl-9-oxo-9-phosphonooxy-nonanoic acid
  参考文献：
  名称：

  The design and synthesis of inhibitors of dethiobiotin synthetase as potential herbicides

  摘要：

  Dethiobiotin synthetase (DTBS;E.C. 6.6.6.6), the penultimate enzyme in the biosynthesis of the essential vitamin biotin, is a new potential target for novel herbicides. Inhibitors were designed based on mechanistic and structural information. The in-vitro activities of these potential inhibitors versus the bacterial enzyme are reported here. Mimics of 7,8-diaminopelargonic acid (DAPA) or the DAPA carbamate reaction intermediate were substrates or partial substrates for the enzyme. Synergistic binding with ATP was noted with compounds which contained an amino functionality, NMR studies and X-ray structures confirmed that the inhibitors could be phosphorylated by the enzyme. Several series of potential inhibitors were designed to take advantage of this partial substrate activity by generating potentially more tightly bound phosphorylated inhibitors in situ, Structure-activity relationships for these series based on both substrate and inhibitory activity are described herein. An X-ray structure for one of these inhibitors is also discussed. Although considerable potential for inhibitors of this type was demonstrated, none of the compounds reported showed sufficient herbicidal activity to be a commercial proposition. (C) 1999 Society of Chemical Industry.

  DOI：

  10.1002/(sici)1096-9063(199903)55:3<236::aid-ps888>3.0.co;2-0
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 生成 3-Methyl-nonandisaeure
  参考文献：
  名称：

  Freer; Perkin jun.,W.H., Journal of the Chemical Society, 1888, vol. 53, p. 218

  摘要：

  DOI：

文献信息

• Studies on the Structure of Itaconitin. VII. The Structures of Itaconitin and Its Derivatives
  作者：Shoichi Nakajima

  DOI：10.1248/cpb.13.73

  日期：——

  It was found that itaconitin, a yellow coloring matter of a mould Aspergillus itaconicus KINOSHITA, possesses a 3, 5-dienoic acid system which is converted into an aromatic ring by the action of acetic anhydride to give acetylanhydroitaconitin. Oxidation of hexahydroitaconitin with potassium permanganate, as well as the ozonolysis of the same substance yielded 2-methylnonanedioic acid. From these and other experimental data including nuclear magnetic resonance spectra, the structural formula of itaconitin and all its derivatives hitherto prepared were conclusively established.

  研究发现，日本木下曲霉（Aspergillus itaconicus KINOSHITA）霉菌的一种黄色着色物质--伊它康尼丁（itaconitin）具有 3，5-二烯酸系统，在醋酸酐的作用下转化为芳香环，从而生成乙酰氢伊它康尼丁（acetylanhydroitaconitin）。用高锰酸钾氧化六氢乌头原素和臭氧分解同一种物质可得到 2-甲基壬二酸。根据这些数据和其他实验数据（包括核磁共振光谱），最终确定了伊塔乌头素及其迄今制备的所有衍生物的结构式。
• REUSABLE PRINT MEDIUM AND METHOD OF MANUFACTURING THEREOF
  申请人：OCE TECHNOLOGIES B.V.

  公开号：US20130137805A1

  公开（公告）日：2013-05-30

  The present invention relates to a reusable print medium comprising a substrate and a sacrificial layer. The sacrificial layer contains a hotmelt composition at least comprising an amorphous material. The amorphous material is a resin being a reaction product of a first monomer A, said first monomer A being a polyhydroxyl alcohol comprising X hydroxyl functional groups, wherein X≧2, monomer A optionally comprises a primary or secondary amine functionality; a second monomer B, being an aromatic monocarboxylic acid; a third monomer C, said third monomer C being able to form an ester linkage with an alcohol and/or an amide linkage with a primary or secondary amine; and optionally, a fourth monomer D, being an aromatic monocarboxylic acid different from the second monomer B. The sacrificial layer including the printed image may be removed from the substrate by applying heat. A new sacrificial layer may be applied such that the reusable print medium is ready to be reused. The present invention also relates to a method of manufacturing a reusable print medium according to the present invention, a method of printing and recycling such a print medium and an apparatus for printing and recycling such a print medium.

  本发明涉及一种可重复使用的印刷介质，包括基底和牺牲层。牺牲层含有至少包括非晶态材料的热熔组合物。该非晶态材料是一种树脂，是第一单体A的反应产物，第一单体A是一种聚羟基醇，包括X个羟基官能团，其中X≥2，单体A可选包括一种主链或侧链氨基官能团；第二单体B是一种芳香单羧酸；第三单体C能够与醇形成酯键和/或与一种主链或侧链氨基形成酰胺键；可选地，第四单体D是一种与第二单体B不同的芳香单羧酸。可以通过施加热量从基底中去除包括印刷图像的牺牲层。可以应用新的牺牲层，使可重复使用的印刷介质准备好被重用。本发明还涉及一种制造可重复使用的印刷介质的方法，一种印刷和回收这样的印刷介质的方法，以及一种印刷和回收这样的印刷介质的装置。
• Polyester and process for producing the same
  申请人：MITSUBISHI KASEI CORPORATION

  公开号：EP0404116A2

  公开（公告）日：1990-12-27

  This invention provides a polyester, which is composed of a constitutive unit of formula (I) and a constitutive unit of formula (II) in a proportion of (I)/(II) of being from 0.1/99.9 to 99.1/0.1 as a molar ratio and which has a logarithmic viscosity (ηinh) of being 0.1 or more: where R₀ is a fluorine-free monovalent organic group having from 1 to 40 carbon atoms, R₁, R₂ and R₃ are independently a divalent organic group having from 1 to 40 carbon atoms, and n is 0 or 1. This invention also provides a method of preparing the polyester, in which (A) a monoepoxy compound of formula (III) where R₀ and n have the same meanings as mentioned above, (B) a polyester or a polyester precursor and (C) a dicarboxylic acid compound are reacted and polymerized.

  本发明提供了一种聚酯，它由式(I)的组成单元和式(II)的组成单元组成，摩尔比(I)/(II)为 0.1/99.9 至 99.1/0.1，对数粘度(ηinh)为 0.1 或以上： 其中 R₀ 是具有 1 至 40 个碳原子的无氟一价有机基团，R₁、R₂ 和 R₃ 独立地是具有 1 至 40 个碳原子的二价有机基团，n 是 0 或 1。 本发明还提供了一种制备聚酯的方法，其中 (A) 式 (III) 的单环氧化合物 其中 R₀ 和 n 的含义与上述相同，(B) 一种聚酯或一种聚酯前体和 (C) 一种二羧酸化合物反应并聚合。
• Multilayer structural material
  申请人：Mitsubishi Chemical Corporation

  公开号：EP0509458A1

  公开（公告）日：1992-10-21

  A resin composition comprising a polyester and a modified polyolefin, wherein said polyester has an amide bond in polymer main chain and said modified polyolefin has a carboxylic acid group or a derivative thereof.

  一种由聚酯和改性聚烯烃组成的树脂组合物，其中所述聚酯在聚合物主链中具有酰胺键，所述改性聚烯烃具有羧酸基或其衍生物。
• RANDOM SILOXANE COPOLYMER, PROCESS FOR PRODUCTION THEREOF, AND RESIN COMPOSITION CONTAINING THE COPOLYMER
  申请人：KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA

  公开号：EP0832913A1

  公开（公告）日：1998-04-01

  The present invention relates to a siloxane random copolymer having a repeating unit represented by the following general formula (I) (II) and (III) at random and a resin composition containing the same. Further, the invention relates to a process of producing a siloxane copolymer comprising the step of reacting at least one polycarbonate and/or dicarbonate of diol and, if needed, at least one diester of dicarboxylic acid with at least one specified silicon compound in the presence of an esterifying or ester exchange catalyst.

  本发明涉及一种硅氧烷无规共聚物，其重复单元由以下通式(I)(II)和(III)无规代表，还涉及一种含有硅氧烷无规共聚物的树脂组合物。 此外，本发明还涉及一种硅氧烷共聚物的生产工艺，该工艺包括以下步骤：在酯化催化剂或酯交换催化剂存在下，使至少一种聚碳酸酯和/或二元醇二碳酸盐，必要时还包括至少一种二羧酸二酯与至少一种指定的硅化合物反应。