ircinamine B

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯啉
• 英文名称: ircinamine B
• 英文别名: 5-Icosylsulfanyl-4-methoxy-3-methylidene-1,2-dihydropyrrole
• 化学式: C₂₆H₄₉NOS
• 分子量: 423.747
• InChiKey: QPMJZXUOGXCBCJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  11.1
• 重原子数：
  29
• 可旋转键数：
  21
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  46.6
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  ircinamine B 在 palladium on activated charcoal 氢气 作用下， 以 甲醇 为溶剂， 生成 3',5'-dihydroircinamine B
  参考文献：
  名称：

  Ircinamine B, bioactive alkaloid from marine sponge Dactylia sp.

  摘要：

  Ircinamine B was isolated from the marine sponge Dactylia sp., which was collected at Cape Sada in Japan. Based on extensive spectral analysis, the structures of the isolated metabolites were established. This novel compound showed moderate activity against the murine leukemia cell line P388 (IC50 0.28 mu g/mL). (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2006.09.020

文献信息

• Ircinamine B, bioactive alkaloid from marine sponge Dactylia sp.
  作者：Seizo Sato、Makoto Kuramoto、Noboru Ono

  DOI：10.1016/j.tetlet.2006.09.020

  日期：2006.11

  Ircinamine B was isolated from the marine sponge Dactylia sp., which was collected at Cape Sada in Japan. Based on extensive spectral analysis, the structures of the isolated metabolites were established. This novel compound showed moderate activity against the murine leukemia cell line P388 (IC50 0.28 mu g/mL). (c) 2006 Elsevier Ltd. All rights reserved.