Claulansine I

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: Claulansine I
• 英文别名: 1-hydroxy-2-(3-methylbut-2-enyl)-9H-carbazole-3-carbaldehyde
• 化学式: C₁₈H₁₇NO₂
• 分子量: 279.3
• InChiKey: QVEMARUSFKFNJG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  53.1
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• Pharmaceutical composition for treating or alleviating an autoimmune disease and/or complication thereof and/or nephritis and method for treating or alleviating an autoimmune disease and/or complication thereof and/or nephritis
  申请人：Industrial Technology Research Institute

  公开号：US10821148B2

  公开（公告）日：2020-11-03

  The present disclosure provides a pharmaceutical composition for treating or alleviating an autoimmune disease and/or complication thereof and/or nephritis, including: an effective amount of an extract of a plant belonging to Rutaceae as an effective ingredient for treating or alleviating the autoimmune disease and/or complication thereof and/or nephritis, wherein the autoimmune disease is selected from a group consisting of lupus erythematosus, psoriasis, psoriatic arthritis, ankylosing spondylitis, rheumatoid arthritis, juvenile idiopathic arthritis, Crohn's disease and ulcerative colitis (UC).

  本公开提供了一种用于治疗或缓解自身免疫性疾病和/或其并发症和/或肾炎的药物组合物，包括：有效量的芸香科植物提取物，作为治疗或缓解自身免疫性疾病和/或其并发症和/或肾炎的有效成分，其中自身免疫性疾病选自由红斑狼疮、银屑病、银屑病关节炎、强直性脊柱炎、类风湿性关节炎、幼年特发性关节炎、克罗恩病和溃疡性结肠炎（UC）组成的组。
• PHARMACEUTICAL COMPOSITION FOR TREATING OR ALLEVIATING AN AUTOIMMUNE DISEASE AND/OR COMPLICATION THEREOF AND/OR NEPHRITIS AND METHOD FOR TREATING OR ALLEVIATING AN AUTOIMMUNE DISEASE AND/OR COMPLICATION THEREOF AND/OR NEPHRITIS
  申请人：Industrial Technology Research Institute

  公开号：US20170258865A1

  公开（公告）日：2017-09-14

  The present disclosure provides a pharmaceutical composition for treating or alleviating an autoimmune disease and/or complication thereof and/or nephritis, including: an effective amount of an extract of a plant belonging to Rutaceae as an effective ingredient for treating or alleviating the autoimmune disease and/or complication thereof and/or nephritis, wherein the autoimmune disease is selected from a group consisting of lupus erythematosus, psoriasis, psoriatic arthritis, ankylosing spondylitis, rheumatoid arthritis, juvenile idiopathic arthritis, Crohn's disease and ulcerative colitis (UC).