Clostrubin B

• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• 英文名称: Clostrubin B
• 英文别名: 17-acetyl-6,10,18,20-tetrahydroxy-4,12-dimethyl-5-(2,3,4-trihydroxy-5-methoxypentanoyl)pentacyclo[11.7.1.0²,⁷.0⁹,²¹.0¹⁴,¹⁹]henicosa-1(21),2(7),3,5,9,11,13,15,17,19-decaen-8-one
• 化学式: C31H28O11
• InChiKey: RYJIESOOJNFJGR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.76
• 重原子数：
  42.0
• 可旋转键数：
  7.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  202.05
• 氢给体数：
  7.0
• 氢受体数：
  11.0

文献信息

• CLOSTRUBINS
  申请人：LEIBNIZ-INSTITUT FÜR NATURSTOFF-FORSCHUNG UND INFEKTIONSBIOLOGIE E.V.

  公开号：US20160340286A1

  公开（公告）日：2016-11-24

  The present invention relates to a bioactive compound according to general formula (I); to a pharmaceutical composition comprising one or more of the compound(s); and to the use of the compound(s) as an antibiotic, cytotoxic and/or anti—proliferative agent.
• [EN] CLOSTRUBINS<br/>[FR] CLOSTRUBINS
  申请人：LEIBNIZ INST FÜR NATURSTOFF FORSCHUNG UND INFEKTIONSBIOLOGIE E V

  公开号：WO2015113761A1

  公开（公告）日：2015-08-06

  The present invention relates to a bioactive compound according to general formula (I); to a pharmaceutical composition comprising one or more of the compound(s); and to the use of the compound(s) as an antibiotic, cytotoxic and/or anti-proliferative agent.