N-(2-methoxyethyl)-2-methylaminoacetamide | 144236-37-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-(2-methoxyethyl)-2-methylaminoacetamide
• 英文别名: N'-(2-methoxyethyl)-N-methylglycinamide；N-(2-methoxyethyl)-2-(methylamino)acetamide
• CAS: 144236-37-3
• 化学式: C₆H₁₄N₂O₂
• mdl: MFCD06658937
• 分子量: 146.189
• InChiKey: IAAQYBLYYCKZOI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.833
• 拓扑面积：
  50.4
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS
  申请人：Philippe Michel

  公开号：US20100028280A1

  公开（公告）日：2010-02-04

  The invention relates to a process for straightening keratin fibres, comprising: (i) a step in which a straightening composition containing at least two denaturing agents is applied to the keratin fibres, (ii) a step in which the temperature of the keratin fibres is raised, using a heating means, to a temperature of between 110 and 250° C.

  该发明涉及一种直发角蛋白纤维的拉直过程，包括：(i)将至少两种变性剂含有的拉直组合物涂抹到角蛋白纤维上的步骤，(ii)使用加热装置将角蛋白纤维的温度升高至110至250°C的步骤。
• [EN] NOVEL 5-SUBSTITUTED BENZIMIDAZOLIUM COMPOUNDS<br/>[FR] NOUVEAUX COMPOSÉS BENZIMIDAZOLIUM SUBSTITUÉS EN POSITION 5
  申请人：BOEHRINGER INGELHEIM INT

  公开号：WO2015007516A1

  公开（公告）日：2015-01-22

  The present invention relates to compounds of general formula (I) and the tautomers and the salts thereof, particularly the pharmaceutically acceptable salts thereof with inorganic or organic acids and bases, which have valuable pharmacological properties, particularly an inhibitory effect on epithelial sodium channels, the use thereof for the treatment of diseases, particularly diseases of the lungs and airways.

  本发明涉及一般式（I）的化合物，以及其互变异构体和盐，特别是其与无机或有机酸和碱形成的药用可接受盐，具有有价值的药理特性，特别是对上皮钠通道具有抑制作用，以及其用于治疗疾病，特别是肺部和气道疾病。
• Novel amphiphilic substance, and drug delivery system and molecular imaging system using the same
  申请人：Akitsu Hitoshi

  公开号：US20080019908A1

  公开（公告）日：2008-01-24

  The present invention provides a novel amphiphilic substance, a nanoparticle using the novel amphiphilic substance, which can be used as a nanocarrier having high biocompatibility, a drug delivery system and a probe useful for the system, and, a molecular imaging system and a probe useful for the system. An amphiphilic block polymer comprising a hydrophilic block; and a hydrophobic block, wherein the hydrophilic block is a hydrophilic polypeptide chain having 10 or more sarcosine units, and the hydrophobic block is a hydrophobic molecular chain comprising units selected from the group consisting of amino acid units and hydroxyl acid units as essential structural units, and having 5 or more of the essential structural units.

  本发明提供了一种新型的两性物质，使用这种新型两性物质制备的纳米粒子可用作具有高生物相容性的纳米载体，药物传递系统以及用于该系统的探针，以及分子成像系统和用于该系统的探针。其中，该两性块聚合物包括一个亲水块；和一个疏水块，其中亲水块是具有10个或更多砒氨酸单元的亲水多肽链，而疏水块是包含氨基酸单元和羟基酸单元等基本结构单元中选择的单位的疏水分子链，并且具有5个或更多基本结构单元。
• [EN] INHIBITORS OF SARM1<br/>[FR] INHIBITEURS DE SARM1
  申请人：DISARM THERAPEUTICS INC

  公开号：WO2021050913A1

  公开（公告）日：2021-03-18

  The present disclosure provides compounds and methods useful for inhibiting SARM1 and/or treating and/or preventing axonal degeneration.

  本公开提供了化合物和方法，用于抑制SARM1和/或治疗和/或预防轴突退化。
• [EN] METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION<br/>[FR] MÉTHODES ET COMPOSITIONS POUR LA DÉGRADATION DE PROTÉINES CIBLÉES
  申请人：RANOK THERAPEUTICS HANGZHOU CO LTD

  公开号：WO2022078470A1

  公开（公告）日：2022-04-21

  Provided are compounds of Formula: H-L-T and pharmaceutically acceptable salts and compositions thereof, which are useful for treating cancers and related conditions.

  提供了公式为H-L-T的化合物及其药物可接受的盐和组合物，这些化合物在治疗癌症及相关疾病方面有用。