parisin

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: parisin
• 英文别名: 3-[2,13-Dihydroxy-13-[5-(1,4,5-trihydroxypentadecyl)oxolan-2-yl]tridecyl]-5-hydroxy-5-methylfuran-2-one；3-[2,13-dihydroxy-13-[5-(1,4,5-trihydroxypentadecyl)oxolan-2-yl]tridecyl]-5-hydroxy-5-methylfuran-2-one
• 化学式: C₃₇H₆₈O₉
• 分子量: 656.942
• InChiKey: USIUGLRYYKXESD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.9
• 重原子数：
  46
• 可旋转键数：
  28
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  157
• 氢给体数：
  6
• 氢受体数：
  9

反应信息

• 作为反应物：
  描述：

  2,2-二甲氧基丙烷 、 parisin 在 对甲苯磺酸 作用下， 以 苯 为溶剂， 反应 1.0h， 以88.6%的产率得到parisin 23,24-acetonide
  参考文献：
  名称：

  Two Unusual Acetogenins from the Roots of Annona salzmanii

  摘要：

  Two new acetogenins, parisin (1) and salzmanolin (2), were isolated from a MeOH extract of the roots of Annona salzmanii. The structures of 1 and 2 were elucidated by spectroscopic methods including LSI-MS/MS, on both the natural compounds and their acetonide derivatives (1a and 2a). Compounds 1 and 2 showed significant activity against the KB and Vero cell lines.

  DOI：

  10.1021/np020543h

文献信息

• Two Unusual Acetogenins from the Roots of <i>Annona </i><i>s</i><i>alzmanii</i>
  作者：Emerson F. Queiroz、François Roblot、Olivier Laprévote、Marçal de Q. Paulo、Reynald Hocquemiller

  DOI：10.1021/np020543h

  日期：2003.6.1

  Two new acetogenins, parisin (1) and salzmanolin (2), were isolated from a MeOH extract of the roots of Annona salzmanii. The structures of 1 and 2 were elucidated by spectroscopic methods including LSI-MS/MS, on both the natural compounds and their acetonide derivatives (1a and 2a). Compounds 1 and 2 showed significant activity against the KB and Vero cell lines.