10,11-dihydroxy-8-(1-hydroxyethyl)-2,4a,6a,6a,9,14a-hexamethyl-3,4,5,6,8,13,14,14b-octahydro-1H-picene-2-carboxylic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• 英文名称: 10,11-dihydroxy-8-(1-hydroxyethyl)-2,4a,6a,6a,9,14a-hexamethyl-3,4,5,6,8,13,14,14b-octahydro-1H-picene-2-carboxylic acid
• 化学式: C₃₁H₄₄O₅
• 分子量: 496.7
• InChiKey: UZTWKCSXTUDYPH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.9
• 重原子数：
  36
• 可旋转键数：
  2
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  98
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• COMPOUNDS THAT MODULATE VON WILLEBRAND FACTOR LEVELS AND THEIR USE IN THE TREATMENT OF BLOOD DISORDERS
  申请人：SOCIETE DES PRODUITS NESTLE S.A.

  公开号：US20210000841A1

  公开（公告）日：2021-01-07

  The present invention relates to a compound having the structure of Formula (I) for use in the prevention or treatment of a blood disorder, in particular by the modulation of von Willebrand factor levels. A nutraceutical product or food product comprising the compound of the invention 5 are also provided.
• [EN] COMPOUNDS THAT MODULATE VON WILLEBRAND FACTOR LEVELS AND THEIR USE IN THE TREATMENT OF BLOOD DISORDERS<br/>[FR] COMPOSÉS QUI MODULENT LES TAUX DE FACTEUR DE VON WILLEBRAND ET LEUR UTILISATION DANS LE TRAITEMENT DE TROUBLES DU SANG
  申请人：NESTLE SA

  公开号：WO2019158359A1

  公开（公告）日：2019-08-22

  The present invention relates to a compound having the structure of Formula (I) for use in the prevention or treatment of a blood disorder, in particular by the modulation of von Willebrand factor levels. A nutraceutical product or food product comprising the compound of the invention 5 are also provided.