Gilvusmycin

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: Gilvusmycin
• 英文别名: 10-[6-(6-acetyl-5-hydroxy-4-methoxy-7,8-dihydro-3H-pyrrolo[3,2-e]indole-2-carbonyl)-5-hydroxy-4-methoxy-7,8-dihydro-3H-pyrrolo[3,2-e]indole-2-carbonyl]-3-methyl-5,10-diazatetracyclo[7.4.0.01,12.02,6]trideca-2(6),3,8-trien-7-one
• 化学式: C₃₈H₃₄N₆O₈
• 分子量: 702.7
• InChiKey: XUBJLJZOSKJNMY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  52
• 可旋转键数：
  4
• 环数：
  10.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  184
• 氢给体数：
  5
• 氢受体数：
  8

文献信息

• Glycopegylation methods and proteins/peptides produced by the methods
  申请人：DeFrees Shawn

  公开号：US20070026485A1

  公开（公告）日：2007-02-01

  The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
• ERYTHROPOIETIN: REMODELING AND GLYCOCONJUGATION OF ERYTHROPOIETIN
  申请人：DeFrees Shawn

  公开号：US20070042458A1

  公开（公告）日：2007-02-22

  The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
• Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
  申请人：DeFrees Shawn

  公开号：US20080050772A1

  公开（公告）日：2008-02-28

  The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
• Factor VIII: Remodeling and glycoconjugation of factor VIII
  申请人：DeFrees Shawn

  公开号：US20080070275A1

  公开（公告）日：2008-03-20

  The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
• Glycoconjugation methods and proteins/peptides produced by the methods
  申请人：DeFrees Shawn

  公开号：US20080146494A1

  公开（公告）日：2008-06-19

  The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.