creatine glycinate | 859980-98-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: creatine glycinate
• 英文别名: 2-Aminoacetic acid;2-[carbamimidoyl(methyl)amino]acetic acid；2-aminoacetic acid;2-[carbamimidoyl(methyl)amino]acetic acid
• CAS: 859980-98-6
• 化学式: C₂H₅NO₂*C₄H₉N₃O₂
• 分子量: 206.202
• InChiKey: AFVPYNARDRCPRO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.07
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  154
• 氢给体数：
  5
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  聚甘氨酸 、 肌酸 以 水 为溶剂， 反应 1.0h， 以97%的产率得到creatine glycinate
  参考文献：
  名称：

  [EN] CREATINE SALT ENHANCED NUTRITIONAL AND THERAPEUTIC EFFICACY AND COMPOSITIONS CONTAINING SAME
  [FR] EFFICACITE THERAPEUTIQUE ET NUTRITIONNELLE AMELIOREE PAR UN SEL DE CREATINE ET COMPOSITIONS RENFERMANT CE SEL

  摘要：

  公开号：

  WO2005089734A3

文献信息

• [EN] TASTE-MODIFIED CREATINE SALTS, COMPOUNDS, COMPOSITIONS AND USES THEREOF<br/>[FR] SELS DE CRÉATINE AU GOÛT MODIFIÉ , COMPOSÉS, COMPOSITIONS ET LEURS UTILISATIONS
  申请人：UNIV RES INST INC AUGUSTA

  公开号：WO2018208647A1

  公开（公告）日：2018-11-15

  Provided are embodiments of creatine and creatine ethyl ester (CEE) salts where the anion is an artificial (non-saccharide) taste-modifier. These compounds represent stable white non-hygroscopic solids or semisolids that can readily dissolve in water and buffer solutions. Synthesis of novel creatine salts using environmentally safe solvents such as ethanol resulted in the formation of products in quantitative yields with sodium or potassium chloride as a byproduct. The creatine and creatine alkyl eater derivative salts are stable sweet-tasting compounds that are more palatable to a consumer than creatine or derivatives thereof.

  提供了肌酸和肌酸乙酯（CEE）盐的实施方式，其中阴离子是人工（非糖类）口味改良剂。这些化合物代表了稳定的白色非吸湿性固体或半固体，可以很容易地溶解在水和缓冲溶液中。使用环保溶剂（如乙醇）合成新型肌酸盐，可以得到产量定量的产物，其副产物为氯化钠或氯化钾。肌酸和肌酸烷基酯衍生物盐是稳定的甜味化合物，比肌酸或其衍生物更适合消费者口味。
• HEMODIALYSIS AND PERITONEAL DIALYSIS SOLUTIONS COMPRISING ONE OR MORE CREATINE COMPOUNDS
  申请人：Crearene Ltd.

  公开号：EP2416770B1

  公开（公告）日：2016-10-26
• Creatine Salt with Enhanced Nutritional and Therapeutic Efficacy and Compositions Containing Same
  申请人：Buononato Antonietta

  公开号：US20080234372A1

  公开（公告）日：2008-09-25

  The novel salt creatine glycinate and compositions (dietary supplements, energy drinks, and dietetic or pharmaceutical products containing the same are described.
• TASTE-MODIFIED CREATINE SALTS, COMPOUNDS, COMPOSITIONS AND USES THEREOF
  申请人：Augusta University Research Institute, Inc.

  公开号：US20200148632A1

  公开（公告）日：2020-05-14

  Provided are embodiments of creatine and creatine ethyl ester (CEE) salts where the anion is an artificial (non-saccharide) taste-modifier. These compounds represent stable white non-hygroscopic solids or semisolids that can readily dissolve in water and buffer solutions. Synthesis of novel creatine salts using environmentally safe solvents such as ethanol resulted in the formation of products in quantitative yields with sodium or potassium chloride as a byproduct. The creatine and creatine alkyl eater derivative salts are stable sweet-tasting compounds that are more palatable to a consumer than creatine or derivatives thereof.
• US7511173B2
  申请人：——

  公开号：US7511173B2

  公开（公告）日：2009-03-31