申请人:Sugawara Shuichi
公开号:US20050113560A1
公开(公告)日:2005-05-26
A body fluid compatible and biocompatible resin for use in a medical treatment involving a contact of said resin with at least one member selected from the group consisting of a body fluid and a biological tissue, which comprises at least one substituted oxyalkylene polymer having a weight average molecular weight of from 1,000 to 1,000,000 and represented by the following formula (1):
wherein each of R
1
, R
2
and R
3
independently represents a hydrogen atom or a —CH
2
R
4
group, and each R
4
independently represents a hydroxyl group or a —OR
5
group (wherein R
5
represents a group selected from the group consisting of a C
1
-C
10
aliphatic hydrocarbyl group, a C
6
-C
10
aryl group, a —R
6
COOH group and a derivative thereof, and a —CH
2
—O—CH
2
—CH(OH)—CH
2
—OR
7
group, wherein R
6
represents a C
1
-C
10
aliphatic hydrocarbylene group and R
7
represents a C
1
-C
10
aliphatic hydrocarbyl group or a C
6
-C
10
aryl group), provided that all of R
1
, R
2
, and R
3
are not simultaneously hydrogen atoms; and 10≦x≦10,000 and 0≦y≦10,000.
一种与体液兼容且生物相容的树脂,用于医疗治疗中与体液或生物组织中的至少一种成员接触,其包括至少一种代替的氧烷基聚合物,其重量平均分子量为1,000至1,000,000,由以下公式(1)表示:
其中,R1、R2和R3分别独立表示氢原子或—CH2R4基团,每个R4独立表示羟基或—OR5基团(其中R5表示从C1-C10脂肪族羟基烃基、C6-C10芳烃基、—R6COOH基团及其衍生物和—CH2—O—CH2—CH(OH)—CH2—OR7基团中选择的基团,其中R6表示C1-C10脂肪族羟基烃基,R7表示C1-C10脂肪族羟基烃基或C6-C10芳烃基),前提是R1、R2和R3不同时为氢原子;且10≦x≦10,000,0≦y≦10,000。