4-(3-aminophenyl)-1-phenyl-6,7-dihydro-5H-cyclopenteno[c]pyridine | 1449416-90-3

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二芳基庚烷
• 英文名称: 4-(3-aminophenyl)-1-phenyl-6,7-dihydro-5H-cyclopenteno[c]pyridine
• 英文别名: 3-(1-phenyl-6,7-dihydro-5H-cyclopenta[c]pyridin-4-yl)aniline
• CAS: 1449416-90-3
• 化学式: C₂₀H₁₈N₂
• 分子量: 286.376
• InChiKey: YTZKRERAIAKUEA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  22
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  38.9
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-溴-3'-硝基苯乙酮 在 sodium acetate 、 溶剂黄146 作用下， 以 乙醇 为溶剂， 反应 16.0h， 生成 4-(3-aminophenyl)-1-phenyl-6,7-dihydro-5H-cyclopenteno[c]pyridine
  参考文献：
  名称：

  Unexpected reduction of the nitro group in (3-nitrophenyl)-1,2,4-triazines during their aza-Diels–Alder reaction with 1-morpholinocyclopentene

  摘要：

  Unexpected reduction of the nitro group to the amino one during aza-Diels-Alder reaction between (3-nitrophenyl)-1,2,4-triazines and 1-morpholinocyclopentene (neat, 200 degrees C, argon) occurred to furnish 4-(3-aminophenyl)-6,7-dihydro-5H-cyclopenta[c]pyridines.

  DOI：

  10.1016/j.mencom.2013.07.010

文献信息

• Unexpected reduction of the nitro group in (3-nitrophenyl)-1,2,4-triazines during their aza-Diels–Alder reaction with 1-morpholinocyclopentene
  作者：Dmitry S. Kopchuk、Albert F. Khasanov、Igor S. Kovalev、Grigory V. Zyryanov、Vladimir L. Rusinov、Oleg N. Chupakhina

  DOI：10.1016/j.mencom.2013.07.010

  日期：2013.7

  Unexpected reduction of the nitro group to the amino one during aza-Diels-Alder reaction between (3-nitrophenyl)-1,2,4-triazines and 1-morpholinocyclopentene (neat, 200 degrees C, argon) occurred to furnish 4-(3-aminophenyl)-6,7-dihydro-5H-cyclopenta[c]pyridines.