acetic acid (2E,8Z)-10-acetoxydeca-2,8-diene-4,6-diyn-1-yl ester | 71867-12-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: acetic acid (2E,8Z)-10-acetoxydeca-2,8-diene-4,6-diyn-1-yl ester
• CAS: 71867-12-4
• 化学式: C₁₄H₁₄O₄
• 分子量: 246.263
• InChiKey: DADBEGIQJYIBBH-FKJILZIQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.23
• 重原子数：
  18.0
• 可旋转键数：
  4.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  52.6
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为产物：
  描述：

  (2E,8Z)-deca-2,8-diene-4,6-diyne-1,10-diol 、 乙酸酐 在 4-二甲氨基吡啶 、 三乙胺 作用下， 以 二氯甲烷 为溶剂， 生成 acetic acid (2E,8Z)-10-acetoxydeca-2,8-diene-4,6-diyn-1-yl ester 、 acetic acid (2E,8E)-10-acetoxydeca-2,8-diene-4,6-diyn-1-yl ester
  参考文献：
  名称：

  Synthesis of isomeric polyacetylenes based on natural hydroxy matricaria esters

  摘要：

  The construction of a library of natural and related polyacetylenes using a convergent synthetic strategy based on a palladium mediated cross-coupling reaction is described. The systematic synthetic study led to all possible alkene isomers of the hydroxy matricaria esters 29-32, and the corresponding tiglates 1-4. The synthesis of many of these compounds is described for the first time. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.07.082

文献信息

• Synthesis of isomeric polyacetylenes based on natural hydroxy matricaria esters
  作者：Solange Garrais、Jennifer Turkington、William P.D. Goldring

  DOI：10.1016/j.tet.2009.07.082

  日期：2009.10

  The construction of a library of natural and related polyacetylenes using a convergent synthetic strategy based on a palladium mediated cross-coupling reaction is described. The systematic synthetic study led to all possible alkene isomers of the hydroxy matricaria esters 29-32, and the corresponding tiglates 1-4. The synthesis of many of these compounds is described for the first time. (C) 2009 Elsevier Ltd. All rights reserved.