isopropyl 15-hydroxypentadecanoate | 77172-46-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: isopropyl 15-hydroxypentadecanoate
• 英文别名: Propan-2-yl 15-hydroxypentadecanoate
• CAS: 77172-46-4
• 化学式: C₁₈H₃₆O₃
• 分子量: 300.482
• InChiKey: OAFIAVNTILACQC-UHFFFAOYSA-N

物化性质

• 沸点：
  385.4±15.0 °C(Predicted)
• 密度：
  0.918±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  21
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  15-羟基十酸 在 对甲苯磺酸 作用下， 以 异丙醇 、 甲苯 为溶剂， 反应 12.0h， 以20%的产率得到环十五内酯
  参考文献：
  名称：

  Formation of macrocyclic lactones in microemulsions

  摘要：

  DOI：

  10.1021/jo00325a037

文献信息

• Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes
  申请人：McDaniel C. Steven

  公开号：US20100210745A1

  公开（公告）日：2010-08-19

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peotide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文公开了一些聚合材料，如涂层、塑料、层压板、复合材料、弹性体、粘合剂或密封剂；一种表面处理，如纺织品涂层或蜡；一种填料，用于这样的聚合材料或表面处理，其中包括一种酶，如酯酶（例如，脂肪水解酶，硫酸酯水解酶，有机磷化合物降解酶），降解细胞壁和/或细胞膜成分的酶（例如，溶菌酶，裂解转糖基酶），生物杀菌或生物静态肽，以及/或肽酶。本文还公开了通过将酶纳入可通过脂肪水解酶、水解酶和/或脲酶的活性交联材料中来改变材料性能，如使用寿命、柔韧性或刚度的方法。
• Anti-fouling Paints and Coatings
  申请人：Reactive Surfaces LTD

  公开号：US20150191607A1

  公开（公告）日：2015-07-09

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peptide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文披露了聚合材料，例如涂层、塑料、层压材料、复合材料、弹性体、粘合剂或密封剂；表面处理，例如纺织品整理或蜡；填充剂，用于这种聚合材料或表面处理，包括酯酶（例如脂肪水解酶、硫酸酯水解酶、有机磷化合物降解酶）的酶，降解细胞壁和/或细胞膜成分的酶（例如溶菌酶、裂解转葡糖苷酶），生物杀菌或生物稳定肽，和/或肽酶。本文还披露了通过将酶并入能够通过脂肪水解酶、水解酶和/或脲酶的活性进行化学交联的材料中，改变材料性能（例如使用寿命、柔韧性或刚度）的方法。
• Amide derivatives and their use in cosmetic composition
  申请人：KAO CORPORATION

  公开号：EP0761644A2

  公开（公告）日：1997-03-12

  An amide derivative represented by the following formula (1): wherein R1 represents a C1-40 hydrocarbon; R2 represents a C1-6 alkylene; R3 represents H, OH or alkoxyl; R4 represents a C1-39 hydrocarbon; R5 represents or -O-R10-R11, with the proviso that when R5 represents or -O-R10-R11, R3 does not represent OH; and a composition of the amide derivative for topical application to human skin. The composition improves the barrier function of the stratum corneum, providing improvement and prevention of dermatitis, skin roughness, or similar disorders.

  由下式(1)代表的酰胺衍生物： 其中 R1 代表 C1-40 碳氢化合物；R2 代表 C1-6 亚烷基；R3 代表 H、OH 或烷氧基；R4 代表 C1-39 碳氢化合物；R5 代表 或-O-R10-R11，但当 R5 代表 或 -O-R10-R11 时，R3 不代表 OH；以及一种用于人体皮肤局部施用的酰胺衍生物组合物。该组合物可改善角质层的屏障功能，改善和预防皮炎、皮肤粗糙或类似疾病。
• GONZALEZ A.; HOLT S. L., J. ORG. CHEM., 1981, 46, NO 12, 2594-2596
  作者：GONZALEZ A.、 HOLT S. L.

  DOI：——

  日期：——
• AMIDE DERIVATIVES AND DERMATOLOGIC PREPARATIONS CONTAINING THE SAME
  申请人：Kao Corporation

  公开号：EP0623124B1

  公开（公告）日：1998-02-18