3-furfuryloxy-1,2-propanediol | 20390-21-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: 3-furfuryloxy-1,2-propanediol
• 英文别名: 2-(2,3-Dihydroxy-propyloxymethyl)-furan；3-furfuryloxy-propane-1,2-diol；3-[(Furan-2-yl)methoxy]propane-1,2-diol；3-(furan-2-ylmethoxy)propane-1,2-diol
• CAS: 20390-21-0
• 化学式: C₈H₁₂O₄
• 分子量: 172.181
• InChiKey: QNHJIUJMUBIEOW-UHFFFAOYSA-N

物化性质

• 沸点：
  141 °C(Press: 4.2 Torr)
• 密度：
  1.2103 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  62.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  3-furfuryloxy-1,2-propanediol 、 碳酸二甲酯 在 四丁基溴化铵 作用下， 180.0 ℃ 、1.1 MPa 条件下， 反应 0.15h， 生成 4-((furan-2-ylmethoxy)methyl)-1,3-dioxolan-2-one
  参考文献：
  名称：

  在有机催化连续流动条件下多功能和可扩展地合成环状有机碳酸酯†

  摘要：

  制备环状有机碳酸酯的基准路线从有毒，挥发性和不稳定的环氧化物开始。在这项工作中，根据替代的可持续和强化连续流动条件，从相应的1,2-二醇制备环状有机碳酸酯。该方法利用碳酸二甲酯（DMC）作为低毒性碳酸化试剂，并依赖于广泛可得的廉价有机铵盐和phospho盐的有机催化活性。选择甘油作为模型底物，用于通过均相铵盐和phospho盐库进行初步优化。阴离子的性质极大地影响催化活性，而阳离子的性质不影响反应。经过优化，在3.5°C的四丁基溴化铵作为有机催化剂的条件下，在180°C（11 bar）下3分钟的停留时间内，能够以95％的转化率和79％的选择性获得碳酸甘油酯。简单的液-液萃取程序既可以纯化碳酸甘油酯，又可以回收均相催化剂。条件适合于精制和粗制生物基甘油，尽管在后一种情况下转化率较低。对照实验表明，粗样品中存在的水会引起碳酸甘油酯的明显水解。然后，将反应条件成功应用于各种底物上，从而提供相应的

  DOI：

  10.1039/c9cy01659g
• 作为产物：
  描述：

  糠基氯 、 甘油 在 sodium 作用下， 以 二氯甲烷 为溶剂， 反应 4.0h， 以90%的产率得到3-furfuryloxy-1,2-propanediol
  参考文献：
  名称：

  一种全生物植物油多元醇及其制备方法和应 用

  摘要：

  本发明公开了一种全生物植物油多元醇及其制备方法和应用，所述方法包括将环氧植物油与式III化合物在第二微结构反应器中反应，得到植物油多元醇。与现有技术相比，本发明采用了新型、绿色的开环试剂，制备得到的多元醇结构新颖，羟值较高且分布均匀，粘度较低，可完全替代传统石化多元醇应用于聚氨酯泡沫材料的制备。同时，本发明工艺方法简单，产品无需进一步处理，适合工业生产。

  公开号：

  CN109111413B

文献信息

• Methods for Obtaining Optically Active Glycidyl Ethers and Optically Active Vicinal Diols from Racemic Substrates
  申请人：Botes Adriana Leonora

  公开号：US20080213833A1

  公开（公告）日：2008-09-04

  The invention provides yeast strains, and polypeptides encoded by genes of such yeast strains, that have enantiospecific glycidyl ether hydrolase activity. The invention also features nucleic acid molecules encoding such polypeptides, vectors containing such nucleic acid molecules, and cells containing such vectors. Also embraced by the invention are methods for obtaining optically active glycidyl ethers and associated optically active vicinal diols.

  本发明提供了具有对映选择性环氧丙烷醚水解酶活性的酵母菌株和由这些酵母菌株基因编码的多肽。本发明还涉及编码这种多肽的核酸分子、含有这种核酸分子的载体以及含有这种载体的细胞。本发明还包括用于获得光学活性环氧丙烷醚及相关光学活性邻二醇的方法。
• METHODS FOR OBTAINING OPTICALLY ACTIVE GLYCIDYL ETHERS AND OPTICALLY ACTIVE VICINAL DIOLS FROM RACEMIC SUBSTRATES
  申请人：Oxyrane UK Limited

  公开号：EP1885849A2

  公开（公告）日：2008-02-13
• Flavor Encapsulation and Method Thereof
  申请人：GROVER Julie Anne

  公开号：US20100189845A1

  公开（公告）日：2010-07-29

  A method for encapsulating flavoring with a prolamin. A prolamin, such as zein, is dissolved in an appropriate solvent. Flavoring is mixed with the prolamin solution. The prolamin and flavoring solution is dried, thereby forming a flavoring encapsulated by a prolamin.
• Methods of Flavor Encapsulation and Matrix-Assisted Concentration of Aqueous Foods and Products Produced Therefrom
  申请人：George Eapen

  公开号：US20110189353A1

  公开（公告）日：2011-08-04

  Flavor encapsulation is generally performed by mixing flavor with a prolamin solution and drying the mixture into powdered forms of encapsulated flavor. In one embodiment, flavor and zein are separately dispersed in an alcohol-water mixture of appropriate ratio prior to mixing. In another embodiment, an aqueous food comprising bioactive components is mixed with the prolamin solution, thereby initiating precipitation of the prolamin and concentration of the bioactive components in said aqueous food. Resulting powdered forms of encapsulated flavor comprise the bioactive components from the aqueous food. In another embodiment, a two-phase drying process may be employed comprising removal of alcohol for evaporation-induced-self-assembly of zein microstructures, followed by removal of remaining water to produce said powdered form.
• CLOSED-CELL TANNIN-BASED FOAMS
  申请人：Cobb Michael W.

  公开号：US20140087175A1

  公开（公告）日：2014-03-27

  Disclosed are foam compositions and processes to form closed-cell tannin-based foams. The foams comprises a continuous polymeric phase defining a plurality of cells, wherein the continuous polymeric phase comprises a tannin-based resin derived from a tannin, a first monomer, and a second monomer, wherein the first monomer comprises formaldehyde, paraformaldehyde, furfural, glyoxal, acetaldehyde, 5-hydroxymethylfurfural, acrolein, levulinate esters, sugars, 2,5-furandicarboxylic acid, 2,5-furandicarboxylic aldehyde, urea, difurfural (DFF), or mixtures thereof, and the second monomer comprises furfuryl alcohol, glycerol, sorbitol, lignin, or mixtures thereof, and wherein the plurality of cells comprises a plurality of open-cells and a plurality of closed-cells with an open-cell content measured according to ASTM D6226-5, of less than 50%. The foam composition also comprises a discontinuous phase disposed in at least a portion of the plurality of closed-cells, the discontinuous phase comprising one or more blowing agents.