3,4,5,6-tetraethylbiphenyl-2-carbaldehyde | 1219618-68-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3,4,5,6-tetraethylbiphenyl-2-carbaldehyde
• 英文别名: 2,3,4,5-Tetraethyl-6-phenylbenzaldehyde
• CAS: 1219618-68-4
• 化学式: C₂₁H₂₆O
• 分子量: 294.437
• InChiKey: NBESFMJCZHJBBI-UHFFFAOYSA-N

物化性质

• 沸点：
  407.7±45.0 °C(Predicted)
• 密度：
  0.989±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  22
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  α-溴代肉桂醛 、 二氯二茂锆 、 3-己炔 在 正丁基锂 作用下， 以 四氢呋喃 为溶剂， 以66%的产率得到3,4,5,6-tetraethylbiphenyl-2-carbaldehyde
  参考文献：
  名称：

  Cycloaddition of Zirconacyclopentadiene with 2-Bromoacrylate, 2-Bromoacrylaldehyde, and 3-Bromofuran-2,5-dione in the Presence of CuCl: A New Pathway for the Formation of Benzene Derivatives and Isobenzofuran-1,3-dione

  摘要：

  Reaction of zirconacyclopentadienes with 2-bromoalkenes in the presence of CuCl afforded multisubstituted benzene derivatives. The reactions of 2-bromoacrylate and 2-bromo-3-phenylacrylaldehyde afforded penta- and hexasubstituted benzenes in good yields. The reaction of 3-bromofuran-2,5-dione with zirconacyclopentadienes gave isobenzofuran-1,3-diones in good yields.

  DOI：

  10.1080/00397910903007053

文献信息

• Cycloaddition of Zirconacyclopentadiene with 2-Bromoacrylate, 2-Bromoacrylaldehyde, and 3-Bromofuran-2,5-dione in the Presence of CuCl: A New Pathway for the Formation of Benzene Derivatives and Isobenzofuran-1,3-dione
  作者：Chao Chen、Xiaoyu Yan、Chanjuan Xi

  DOI：10.1080/00397910903007053

  日期：2010.2.2

  Reaction of zirconacyclopentadienes with 2-bromoalkenes in the presence of CuCl afforded multisubstituted benzene derivatives. The reactions of 2-bromoacrylate and 2-bromo-3-phenylacrylaldehyde afforded penta- and hexasubstituted benzenes in good yields. The reaction of 3-bromofuran-2,5-dione with zirconacyclopentadienes gave isobenzofuran-1,3-diones in good yields.