4-mer-HCA | 1382735-27-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-mer-HCA
• 英文别名: 3,3'''-Dihydroxy-2',2'',5',5''-tetramethyl-[1,1':4',1'':4'',1'''-quaterphenyl]-4,4'''-dicarboxylic acid；4-[4-[4-(4-carboxy-3-hydroxyphenyl)-2,5-dimethylphenyl]-2,5-dimethylphenyl]-2-hydroxybenzoic acid
• CAS: 1382735-27-4
• 化学式: C₃₀H₂₆O₆
• 分子量: 482.533
• InChiKey: OXYVNYNENAKAPF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.7
• 重原子数：
  36
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  115
• 氢给体数：
  4
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  4-mer-HCA 在 palladium on activated charcoal 、 氢气 作用下， 以 乙醇 、 乙酸乙酯 为溶剂， 生成 4-mer-HCA
  参考文献：
  名称：

  MOLECULAR GAUGE BLOCKS FOR BUILDING ON THE NANOSCALE

  摘要：

  本公开涉及一种生产一系列离散尺寸细长、刚性寡聚对二甲苯分子的方法，其长度范围为1-5纳米。基于1-7、9-11对二甲苯环的分子已经合成，作为寡聚对二甲苯（OPXs）同系列的一部分，旨在提供一个分子工具箱，用于构建纳米结构，例如球体、笼子、胶囊、金属有机框架（MOFs）、金属有机多面体（MOPs）和共价有机框架（COFs）等，以明确定义的尺寸和形状。相邻对二甲苯环之间的平面扭曲是由于与甲基基团相关的立体位阻所产生的，导致可溶性分子测量块的存在，而不需要在分子中引入长脂肪侧链，至少在较低同系物的情况下。

  公开号：

  US20130122297A1

文献信息

• METAL-ORGANIC FRAMEWORKS WITH EXCEPTIONALLY LARGE PORE APERATURES
  申请人：CALIFORNIA THE REGENTS OF THE UNIVERSITY OF

  公开号：US20130096210A1

  公开（公告）日：2013-04-18

  The disclosure relates to metal organic frameworks or isoreticular metal organic frameworks, methods of production thereof, and methods of use thereof.

  该披露涉及金属有机框架或同构金属有机框架的生产方法以及使用方法。
• Molecular Gauge Blocks for Building on the Nanoscale
  作者：Sergio Grunder、Cory Valente、Adam C. Whalley、Srinivasan Sampath、Jürg Portmann、Youssry Y. Botros、J. Fraser Stoddart

  DOI：10.1002/chem.201201985

  日期：2012.12.3

  by the steric hindrance associated with the methyl groups and leads to the existence of soluble molecular gauge blocks without the need, at least in the case of the lower homologues, to introduce long aliphatic side chains onto the phenylene rings in the molecules. Although soluble molecular gauge blocks with up to seven consecutive benzenoid rings have been prepared employing repeating paraxylene units

  作为低聚对二甲苯（OPX）同源系列的一部分，已经合成了基于1–7、9–11对二甲苯环的分子规嵌段，以期提供用于构建纳米结构（例如球体）的分子工具箱。笼子，胶囊，金属有机框架（MOF），金属有机多面体（MOP）和共价有机框架（COF）等，其中只有几个-定义明确的尺寸和形状。对位二甲苯​​环平面之间的扭曲是由于与甲基相关的位阻而产生的，并导致存在可溶性分子规嵌段，至少在较低的同系物的情况下，不需要在其上引入长的脂族侧链分子中的亚苯基环。尽管已经使用重复的对二甲苯单元制备了具有多达七个连续的苯环的可溶性分子规嵌段，但是在较高的同系物的情况下，有必要在选择的亚苯基环上引入己基而不是甲基来保持溶解性。发现具有七个取代的亚苯基环的己基掺杂化合物是有机胶凝剂，具有可热逆凝胶化作用，临界胶凝浓度为10 mM在二甲基亚砜中。此外，根据通过扫描电子显微镜获得的图像，观察到对一系列己基掺杂OPX的形态进行控制，
• METAL-ORGANIC FRAMEWORK/STIMULUS-RESPONSIVE POLYMER COMPOSITE CAPABLE OF CONTROLLING RELEASE OF GUEST
  申请人：National University Corporation Hokkaido University

  公开号：EP3141263A1

  公开（公告）日：2017-03-15

  A metal-organic framework (MOF) having the function of controlling the release of guests is provided in which reversible release control is possible and release control can be rapidly performed and which is capable of accommodating the release of various guest molecules. The metal-organic framework comprises both an organic ligand having two or more functional groups (coordinating functional groups) capable of coordinating to a metal atom and metal ions that combine with the coordinating functional groups of the organic ligand, and has a structure in which one metal ion has combined with two or more of the coordinating functional groups to connect multiple molecules of the organic ligand. The metal-organic framework/stimulus-responsive polymer composite was obtained by affixing a stimulus-responsive polymer to at least some of the surface of the metal-organic framework. The stimulus-responsive polymer may be affixed by bonding to the organic ligand.

  本发明提供了一种具有控制客体释放功能的金属有机框架（MOF），该框架可实现可逆释放控制，并能快速进行释放控制，而且能够容纳各种客体分子的释放。金属有机框架包括具有两个或两个以上能与金属原子配位的官能团（配位官能团）的有机配体和与有机配体的配位官能团结合的金属离子，并具有一个金属离子与两个或两个以上配位官能团结合以连接多个有机配体分子的结构。金属有机框架/刺激响应型聚合物复合材料是通过将刺激响应型聚合物粘贴到金属有机框架的至少部分表面而获得的。刺激响应型聚合物可通过与有机配体键合来粘贴。
• METAL-ORGANIC FRAMEWORK STIMULUS RESPONSIVE POLYMER COMPOSITE CAPABLE OF CONTROLLING RELEASE OF GUEST
  申请人：NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY

  公开号：US20170072070A1

  公开（公告）日：2017-03-16

  A metal-organic framework (MOF) having the function of controlling the release of guests is provided in which reversible release control is possible and release control can be rapidly performed and which is capable of accommodating the release of various guest molecules. The metal-organic framework comprises both an organic ligand having two or more functional groups (coordinating functional groups) capable of coordinating to a metal atom and metal ions that combine with the coordinating functional groups of the organic ligand, and has a structure in which one metal ion has combined with two or more of the coordinating functional groups to connect multiple molecules of the organic ligand. The metal-organic framework/Stimulus-responsive polymer composite was obtained by affixing a stimulus-responsive polymer to at least some of the surface of the metal-organic framework. The stimulus-responsive polymer may be affixed by bonding to the organic ligand.
• US9078922B2
  申请人：——

  公开号：US9078922B2

  公开（公告）日：2015-07-14