1,3,5-triazine-2-iminodiacetic acid-4,6-biglycine | 945035-88-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 1,3,5-triazine-2-iminodiacetic acid-4,6-biglycine
• 英文别名: 2-[[4-[Bis(carboxymethyl)amino]-6-(carboxymethylamino)-1,3,5-triazin-2-yl]amino]acetic acid
• CAS: 945035-88-1
• 化学式: C₁₁H₁₄N₆O₈
• 分子量: 358.268
• InChiKey: AHFNSTUXFRYWDV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  25
• 可旋转键数：
  11
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  215
• 氢给体数：
  6
• 氢受体数：
  14

反应信息

• 作为反应物：
  描述：

  terbium(III) nitrate hexahydrate 、 1,3,5-triazine-2-iminodiacetic acid-4,6-biglycine 、 水 在 盐酸 作用下， 反应 72.0h， 以41%的产率得到
  参考文献：
  名称：

  由三嗪基柔性多羧酸盐配体组装而成的镧系配位聚合物及其发光性能†

  摘要：

  两个基于三嗪的柔性聚羧酸盐配体，1,3,5-三嗪-2-亚氨基二乙酸-4,6-双（L-丙氨酸）（H 4 L1）和1,3,5-三嗪-2-亚氨基二乙酸- 4,6-联甘氨酸（H 4 L2）已被设计并用于构建一系列发光镧系配位聚合物{[Ln（HL1）]（H 2 O）5 } n（Ln = 1，Tb；2，Eu ; 3，Gd）和{[Ln（HL2）（H 2 O）]（H 2 O）2 } n（Ln = 4，Tb; 5，Eu; 6，Gd）。通过单晶X射线衍射对复合物进行结构鉴定，结果表明，衍生自H 4 L1的同构复合物1-3具有单斜空间群C 2 / c的2-D构架，而同构复合物4–6，基于H 4 L2，显示具有单斜空间群P 2（1）/ c的二维层结构。研究了复合物的固态光致发光性质。配合物1和2表现出显着的绿色和红色发光发射，分别具有高达67％和68％的高量子产率以及毫秒级的寿命。然而，配合物4和5的量子产率很弱（4为9

  DOI：

  10.1039/c3ce27020c
• 作为产物：
  描述：

  2-[Carboxymethyl-(4,6-dichloro-1,3,5-triazin-2-yl)amino]acetic acid 、 聚甘氨酸 在 sodium hydroxide 作用下， 以 水 为溶剂， 反应 0.17h， 以84%的产率得到1,3,5-triazine-2-iminodiacetic acid-4,6-biglycine
  参考文献：
  名称：

  Facile and efficient synthesis of C2-symmetrical 1,3,5-triazine polycarboxylate ligands under microwave irradiation

  摘要：

  A rapid and efficient method for preparation of C-2-symmetrical 1,3,5-triazine polycarboxylate ligands was developed. The reactions included either selective mono- or di-substitution of 2,4,6-trichloro-1,3,5-triazine with various nucleophiles containing carboxyl group(s), followed by nucleophilic displacement of the remained chloride(s) in aqueous media under microwave irradiation. Novel C-2-symmetrical tripodal ligands were afforded in good yields and purities under short reaction time with simple work-up, which are potentially useful as structural directing units in metal-organic frameworks. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2014.06.127

文献信息

• Method for Producing a Compound with at Least One at Least Monosubstituted Amino Group
  申请人：Dicke Rene

  公开号：US20110105654A1

  公开（公告）日：2011-05-05

  The invention relates to a method for producing a compound having at least one mono substituted amino group. According to the invention, a starting substance supporting at least one amino group as reacted with a reagent supporting a first functional group and at least one other functional group in a reaction mixture. The first functional group is a hydroxyl group and the at least one other functional group is selected from hydroxyl groups, mercapto groups, carboxylic acid groups, carboxylic acid ester groups, carboxylic acid amide groups, keto groups, carbonate groups, halogens, epoxy groups and carbamate groups. If several other functional groups are present, the groups are selected independently of one another from the aforementioned class. Melamine, urea and guanamine are, in particular, reacted with glycol, glycerine and hydroxyl acetic acid derivatives.
• Facile and efficient synthesis of C2-symmetrical 1,3,5-triazine polycarboxylate ligands under microwave irradiation
  作者：Watcharee Funfuenha、Wong Phakhodee、Mookda Pattarawarapan

  DOI：10.1016/j.tet.2014.06.127

  日期：2014.9

  A rapid and efficient method for preparation of C-2-symmetrical 1,3,5-triazine polycarboxylate ligands was developed. The reactions included either selective mono- or di-substitution of 2,4,6-trichloro-1,3,5-triazine with various nucleophiles containing carboxyl group(s), followed by nucleophilic displacement of the remained chloride(s) in aqueous media under microwave irradiation. Novel C-2-symmetrical tripodal ligands were afforded in good yields and purities under short reaction time with simple work-up, which are potentially useful as structural directing units in metal-organic frameworks. (C) 2014 Elsevier Ltd. All rights reserved.
• Lanthanide coordination polymers assembled from triazine-based flexible polycarboxylate ligands and their luminescent properties
  作者：Yihui Huang、Qilong Zhu、Tianlu Sheng、Shengmin Hu、Ruibiao Fu、Chaojun Shen、Chunhong Tan、Yuehong Wen、Songyan Bai、Xintao Wu

  DOI：10.1039/c3ce27020c

  日期：——

  1,3,5-triazine-2-iminodiacetic acid-4,6-bis(L-alanine) (H4L1) and 1,3,5-triazine-2-iminodiacetic acid-4,6-biglycine (H4L2), have been designed and used to construct a series of luminescent lanthanide coordination polymers [Ln(HL1)](H2O)5}n (Ln = 1, Tb; 2, Eu; 3, Gd) and [Ln(HL2)(H2O)](H2O)2}n (Ln = 4, Tb; 5, Eu; 6, Gd). The complexes were structurally authenticated by single-crystal X-ray diffraction

  两个基于三嗪的柔性聚羧酸盐配体，1,3,5-三嗪-2-亚氨基二乙酸-4,6-双（L-丙氨酸）（H 4 L1）和1,3,5-三嗪-2-亚氨基二乙酸- 4,6-联甘氨酸（H 4 L2）已被设计并用于构建一系列发光镧系配位聚合物[Ln（HL1）]（H 2 O）5 } n（Ln = 1，Tb；2，Eu ; 3，Gd）和[Ln（HL2）（H 2 O）]（H 2 O）2 } n（Ln = 4，Tb; 5，Eu; 6，Gd）。通过单晶X射线衍射对复合物进行结构鉴定，结果表明，衍生自H 4 L1的同构复合物1-3具有单斜空间群C 2 / c的2-D构架，而同构复合物4–6，基于H 4 L2，显示具有单斜空间群P 2（1）/ c的二维层结构。研究了复合物的固态光致发光性质。配合物1和2表现出显着的绿色和红色发光发射，分别具有高达67％和68％的高量子产率以及毫秒级的寿命。然而，配合物4和5的量子产率很弱（4为9