(phenoxymethyl)succinic anhydride | 1393661-19-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: (phenoxymethyl)succinic anhydride
• 英文别名: 3-(Phenoxymethyl)oxolane-2,5-dione；3-(phenoxymethyl)oxolane-2,5-dione
• CAS: 1393661-19-2
• 化学式: C₁₁H₁₀O₄
• 分子量: 206.198
• InChiKey: XDIXPRGHFHTCHE-UHFFFAOYSA-N

物化性质

• 沸点：
  382.1±15.0 °C(Predicted)
• 密度：
  1.271±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  马来酸酐 、 苯氧乙酸 在 dioxide titanium 作用下， 以 乙腈 为溶剂， 反应 26.0h， 以34%的产率得到(phenoxymethyl)succinic anhydride
  参考文献：
  名称：

  Unconventional Titania Photocatalysis: Direct Deployment of Carboxylic Acids in Alkylations and Annulations

  摘要：

  Under dry, anaerobic conditions, TiO2 photocatalysis of carboxylic add precursors resulted in carbon-carbon bond-forming processes. High yields of dirners were obtained from TiO2 treatment of carboxylic acids alone: On inclusion of electron-deficient alkenes, efficient alkylations were achieved with methoxymethyl and phenoxymethyl radicals. In reactions with maleic anhydride or maleimides, phenoxyacetic acid produced chromenedione derivatives in addition to adducts. These photocatalytic reactions are simple and cheap to perform, and the TiO2 is easily removed by filtration. The anaerobic photocatalysis strategy offers a range of synthetic possibilities.

  DOI：

  10.1021/ja306168h

文献信息

• Unconventional Titania Photocatalysis: Direct Deployment of Carboxylic Acids in Alkylations and Annulations
  作者：David W. Manley、Roy T. McBurney、Phillip Miller、Russell F. Howe、Shona Rhydderch、John C. Walton

  DOI：10.1021/ja306168h

  日期：2012.8.22

  Under dry, anaerobic conditions, TiO2 photocatalysis of carboxylic add precursors resulted in carbon-carbon bond-forming processes. High yields of dirners were obtained from TiO2 treatment of carboxylic acids alone: On inclusion of electron-deficient alkenes, efficient alkylations were achieved with methoxymethyl and phenoxymethyl radicals. In reactions with maleic anhydride or maleimides, phenoxyacetic acid produced chromenedione derivatives in addition to adducts. These photocatalytic reactions are simple and cheap to perform, and the TiO2 is easily removed by filtration. The anaerobic photocatalysis strategy offers a range of synthetic possibilities.