2-hydroxypropyl sorbate | 88973-77-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-hydroxypropyl sorbate
• 英文别名: 2,4-Hexadienoic acid, 2-hydroxypropyl ester, (2E,4E)-；2-hydroxypropyl (2E,4E)-hexa-2,4-dienoate
• CAS: 88973-77-7
• 化学式: C₉H₁₄O₃
• 分子量: 170.208
• InChiKey: HVTJOXLPLJPOJO-VNKDHWASSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  山梨酸 、 1,2-丙二醇 以29%的产率得到2-hydroxypropyl sorbate
  参考文献：
  名称：

  Le Baut; Sparfel; Clairc, European Journal of Medicinal Chemistry, 1983, vol. 18, # 5, p. 441 - 445

  摘要：

  DOI：

文献信息

• [EN] PREPARATION OF A SORBATE ESTER<br/>[FR] PRÉPARATION D'UN ESTER DE SORBATE
  申请人：DOW GLOBAL TECHNOLOGIES LLC

  公开号：WO2016061756A1

  公开（公告）日：2016-04-28

  The present invention is a process for preparing a sorbate ester comprising the steps of: a) contacting together in a reaction vessel a first organic solvent, sorbic acid, a catalytic amount of TiCl4, an anti-oxidant, and an alkylene oxide under conditions sufficient to form a mixture of the sorbate ester and residual water-soluble impurities; then b) separating the sorbate ester from the residual water-soluble impurities by washing. Sorbate esters can be prepared in an efficient and cost-effective manner by the process of the present invention.

  本发明是一种制备山梨酸酯的方法，包括以下步骤：a）在反应容器中将第一有机溶剂、山梨酸、催化剂量的TiCl4、抗氧化剂和一种烷基氧化物接触，以形成山梨酸酯和残留的水溶性杂质的混合物；然后b）通过洗涤将山梨酸酯与残留的水溶性杂质分离。本发明的方法可以高效、经济地制备山梨酸酯。
• [EN] PREPARATION OF SORBATE ESTER<br/>[FR] PRÉPARATION D'ESTER DE SORBATE
  申请人：DOW GLOBAL TECHNOLOGIES LLC

  公开号：WO2016061760A1

  公开（公告）日：2016-04-28

  Disclosed is a process for preparing a hydroxyalkyl sorbate comprising the steps of of: a) contacting together in a reaction vessel a solvent, sorbic acid, a transition metal halide catalyst, an anti-oxidant, and an alkylene oxide under conditions sufficient to form the hydroxyalkyl sorbate; b) removing the solvent in vacuo, wherein the anti-oxidant is characterized by the following formula or a carboxylic acid salt thereof: wherein Y, x, and R1 are defined herein. The process provides a convenient way of preparing hydroxyalkyl sorbates in high yield and purity without complicated workup steps.

  本发明揭示了一种制备羟基烷基山梨酸酯的方法，包括以下步骤：a)在反应容器中将溶剂、山梨酸、过渡金属卤化物催化剂、抗氧化剂和烷氧基在足够的条件下接触以形成羟基烷基山梨酸酯；b)在真空下去除溶剂，其中抗氧化剂具有以下公式或其羧酸盐：其中Y、x和R1在此定义。该方法提供了一种方便的方式，以高收率和高纯度制备羟基烷基山梨酸酯，而无需复杂的工艺步骤。
• Methods of producing alkylene glycol monosorbates
  申请人：CHISSO CORPORATION

  公开号：EP0387654A2

  公开（公告）日：1990-09-19

  The invention provides a method of producing alkylene glycol monosorbates which comprises reacting sorbic acid and an alkylene oxide having 2 to 4 carbon atoms in a certain system containing a solvent inactive to the alkylene glycol monosorbates, one or more iron catalysts and one or more compounds consisting of phenothiazines and alkylphenols, washing the obtained synthesized liquid with an aqueous (bi)carbonate solution, and then purify­ing the washed liquid by distillation, and a method of reserving the alkylene glycol monosorbates.

  本发明提供了一种生产烷二醇单吸附剂的方法，该方法包括在含有对烷二醇单吸附剂不活泼的溶剂、一种或多种铁催化剂和一种或多种由吩噻嗪和烷基酚组成的化合物的特定体系中，使山梨酸和具有 2 至 4 个碳原子的氧化亚烷反应，用（双）碳酸盐水溶液洗涤得到的合成液，然后通过蒸馏提纯洗涤液，以及保留烷二醇单吸附剂的方法。
• Methods of producing and preserving alkylene glycol monosorbates
  申请人：CHISSO CORPORATION

  公开号：EP0559239A1

  公开（公告）日：1993-09-08

  The invention provides a method of preserving an alkylene glycol monosorbate, characterized in that the method comprises adding one or more compounds selected from the group consisting of alkylphenols and phenothiazines to the alkylene glycol monosorbate and stirring to mix them, removing oxygen from a vessel containing the mixture, and sealing hermetically the vessel.

  本发明提供了一种保存烷二醇单山梨醇酯的方法，其特征在于该方法包括向烷二醇单山梨醇酯中加入一种或多种选自烷基酚和吩噻嗪类的化合物，并搅拌使其混合，从装有混合物的容器中除去氧气，然后密封容器。
• SORBIC ACID ESTER COMPOSITION
  申请人：Dow Global Technologies LLC

  公开号：EP3029116A1

  公开（公告）日：2016-06-08

  The present invention is a method comprising the steps of a) applying a composition comprising a curing agent and a cure modulating additive to a substrate; and b) allowing the composition to cure. The curing agent is a sorbic acid ester or a sorbamide and the cure modulating agent is a reagent capable of modulating the rate of cure of the curing agent.

  本发明是一种方法，包括以下步骤：a) 将包含固化剂和固化调节添加剂的组合物施用于基材；b) 使组合物固化。固化剂是山梨酸酯或山梨酰胺，固化调节剂是能够调节固化剂固化速率的试剂。