10-Azido-1-decanethiol | 1152113-44-4

• 分子结构分类: 有机化合物 - 有机1,3-偶极化合物 - 烯丙基型1,3-偶极有机化合物
• 英文名称: 10-Azido-1-decanethiol
• 英文别名: 10-azidodecane-1-thiol
• CAS: 1152113-44-4
• 化学式: C10H21N3S
• 分子量: 215.36
• InChiKey: BKCBIRSZMTUUDA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  14
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  15.4
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF
  申请人：Roche Diagnostics Operations, Inc.

  公开号：US20190324025A1

  公开（公告）日：2019-10-24

  The present invention relates to a monoclonal antibody capable of binding to biotin. In one embodiment the monoclonal antibody according to the invention also does not bind to a biotin moiety on a biotinylated molecule, wherein the biotin moiety is attached to the molecule via the carbon atom of the carboxyl function of the valeric acid moiety of biotin. Also disclosed is a method for generation of an antibody as disclosed herein. The monoclonal antibody according to the invention is of specific use in a method for measuring an analyte in a sample, wherein a (strept)avidin/biotin pair is used to bind a biotinylated analyte specific binding agent to a (strept)avidin coated solid phase.