N,N'-bis<9(Z)-octadecenoylamino>methane | 10436-16-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: N,N'-bis<9(Z)-octadecenoylamino>methane
• 英文别名: N,N'-Methylen-bis-(9-octadecenoylamid)；N,N'-Methylenebis(oleamide), (Z, Z)-；(Z)-N-[[[(Z)-octadec-9-enoyl]amino]methyl]octadec-9-enamide
• CAS: 10436-16-5
• 化学式: C₃₇H₇₀N₂O₂
• 分子量: 574.975
• InChiKey: JAPRZGVSYUJXTI-CLFAGFIQSA-N

物化性质

• 熔点：
  118.1 °C
• 沸点：
  719.4±60.0 °C(Predicted)
• 密度：
  0.900±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  13.9
• 重原子数：
  41
• 可旋转键数：
  32
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.84
• 拓扑面积：
  58.2
• 氢给体数：
  2
• 氢受体数：
  2

安全信息

• 海关编码：
  2924199090

反应信息

• 作为产物：
  描述：

  二碘甲烷 、 油酸酰胺 在 碘 、 铜 作用下， 以 甲苯 为溶剂， 反应 48.0h， 以35%的产率得到N,N'-bis<9(Z)-octadecenoylamino>methane
  参考文献：
  名称：

  Structure Determination of an Endogenous Sleep-Inducing Lipid, cis-9-Octadecenamide (Oleamide):  A Synthetic Approach to the Chemical Analysis of Trace Quantities of a Natural Product

  摘要：

  The pursuit of endogenous sleep-inducing substances has been the focus of an extensive, complicated body of research. Several compounds, including Delta-sleep-inducing peptide and prostaglandin D-2, have been suggested to play a role in sleep induction, and yet, the molecular mechanisms of this physiological process remain largely unknown. In recent efforts, the cerebrospinal fluid of deep-deprived cats was analyzed in search of compounds that accumulated during sleep deprivation. An agent with the chemical formula C18H35NO was found to cycle with sleep-wake patterns, increasing in concentration with sleep deprivation and decreasing in amount upon recovery sleep. Since the material was generated in minute quantities and only under the special conditions of sleep deprivation, efforts to isolate sufficient material for adequate characterization, structure identification, and subsequent detailed evaluation of its properties proved unrealistic. With the trace amounts of the impure endogenous compound available, extensive MS studies on the agent were completed, revealing key structural features of the molecule including two degrees of unsaturation, a long alkyl chain, and a nitrogen substituent capable of fragmenting as ammonia. Additionally, HPLC traces suggested a weak UV absorbance for the unknown material. With this data in hand and encouraged by the relatively small size of the molecule, MW = 281, a synthetic approach toward the structural identification of the natural compound was initiated. Herein, we report the full details of the synthesis and comparative characterization of candidate structures for this endogenous agent that led to the unambiguous structural correlation with synthetic cis-9-octadecenamide.

  DOI：

  10.1021/ja9532345

文献信息

• Polyolefin composition
  申请人：Ito Yuichi

  公开号：US20100004401A1

  公开（公告）日：2010-01-07

  [Problem] A polyolefin composition comprising an olefin-based thermoplastic elastomer which is superior to conventional olefin-based thermoplastic elastomers in scratch resistance and abrasion resistance and has excellent heat aging resistance is proposed. [Means for Solving the Problem] A polyolefin composition comprising a syndiotactic α-olefin-based copolymer (A), a polyolefin resin (B) (other than polybutene (C)), polybutene (C), and if necessary, an ethylene-based copolymer rubber (D).

  [问题]提出了一种聚烯烃组合物，其中包括一种基于烯烃的热塑性弹性体，其在抗刮擦和抗磨损方面优于传统的基于烯烃的热塑性弹性体，并具有优异的耐热老化性能。 [解决问题的方法]该聚烯烃组合物包括一个顺反式α-烯烃基共聚物(A)，一个聚烯烃树脂(B)(不包括聚丁烯(C))，聚丁烯(C)，如果需要，还包括一种乙烯基共聚物橡胶(D)。
• THERMOPLASTIC ELASTOMER COMPOSITION FOR FOAMING, MOLDED FOAM THEREOF, COMPOSITE MOLDED PRODUCT USING THE MOLDED FOAM, AND INSTRUMENT PANEL FOR AUTOMOBILE
  申请人：KURITA Hayato

  公开号：US20110117358A1

  公开（公告）日：2011-05-19

  [Problem] To provide a thermoplastic elastomer composition for foaming, which has sufficient foamability and provides a molded article having good appearance. [Solution to Problem] A thermoplastic elastomer composition for foaming, which comprises 10 to 40% by weight of a partially or completely crosslinked ethylene/α-olefin/non-conjugated polyene copolymer rubber (A) comprising ethylene, an α-olefin of 3 to 20 carbon atoms and a non-conjugated polyene, 3 to 33% by weight of an ethylene/α-olefin copolymer (B) comprising ethylene and an α-olefin of 3 to 20 carbon atoms, 10 to 40% by weight of polypropylene (C) having a melting point, as determined by differential scanning calorimetry (DSC), of 40 to 170° C., 10 to 45% by weight of a softener (D) for rubbers, and at least one substance selected from an isotactic propylene-based polymer (E-a) in an amount of 1 to 30% by weight and a syndiotactic α-olefin-based copolymer (E-b) in an amount of 1 to 20% by weight, with the proviso that the total amount of the components (A), (B), (C), (D), (E-a) and (E-b) is 100% by weight.

  [问题] 提供一种热塑性弹性体泡沫组合物，具有足够的泡沫性和提供外观良好的成型品。[解决方案] 一种热塑性弹性体泡沫组合物，包括：10％至40％重量的部分或完全交联的乙烯/α-烯烃/非共轭多烯共聚物橡胶（A），其中包括乙烯，3至20个碳原子的α-烯烃和非共轭多烯；3％至33％重量的乙烯/α-烯烃共聚物（B），其中包括乙烯和3至20个碳原子的α-烯烃；10％至40％重量的聚丙烯（C），其熔点由差示扫描量热法（DSC）确定为40至170℃；10％至45％重量的橡胶软化剂（D）；以及至少选择一种物质，所述物质从在1至30％重量范围内的异构聚丙烯基聚合物（E-a）和在1至20％重量范围内的顺反式α-烯烃基共聚物（E-b）中选择，但前提是组分（A），（B），（C），（D），（E-a）和（E-b）的总量为100％重量。
• Process for producing pre-expanded particles of a polyolefin
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0323719A2

  公开（公告）日：1989-07-12

  A process for producing pre-expanded particles of a thermoplastic resin, wherein said particles are of a polyolefin obtained by polymerizing an olefin in the presence of a Ziegler-Natta catalyst, and contain not more than 1% by weight of particles of diameter up to 105 µm and having a particle size distribution represented by:R(Dp) = 100exp[-(Dp/De)n] where Dp is300 or more and represents a particle diameter (µ m); R(Dp) represents a cumulative weight percentage; De represents an absolute size constant that is a particle diameter (µm) corresponding to R(Dp) 36.8% by weight; and n is 25 or more and is a distribution constant. The process can be carried out by dispersing the particles in a liquid medium (e.g. water) containing a blowing agent (e.g. an aliphatic hydrocarbon) and a phenolic antioxidant, heating to above the softening point of the polymer, and releasing the dispersion into a zone of lower pressure. Pre-expanded polyolefin particles free from scatters of cell diameter or particle diameter and having a high expansion ratio are obtained, which can be put into a mold for expansion molding to easily provide a uniformly expanded article.

  一种生产热塑性树脂预膨化颗粒的工艺，其中所述颗粒为在齐格勒-纳塔催化剂存在下通过聚合烯烃而获得的聚烯烃，且含有不超过 1%（按重量计）的颗粒，其直径不超过 105 µm，其粒度分布用以下公式表示：R(Dp) = 100exp[-(Dp/De)n]，其中 Dp 为 300 或以上，代表颗粒直径 (µ m)；R(Dp) 代表累积重量百分比；De 代表绝对粒度常数，即与 R(Dp) 36.8%（重量百分比）；n 为 25 或更多，是分布常数。 该工艺可通过将颗粒分散在含有发泡剂（如脂肪烃）和酚类抗氧化剂的液体介质（如水）中，加热至聚合物软化点以上，然后将分散体释放到压力较低的区域来实现。 得到的预膨化聚烯烃颗粒没有细胞直径或颗粒直径的散射，具有较高的膨化率，可将其放入模具中进行膨化成型，从而很容易得到膨化均匀的制品。
• Container for photographic film cartridge
  申请人：FUJI PHOTO FILM CO., LTD.

  公开号：EP0385199A2

  公开（公告）日：1990-09-05

  Container bodies for a photographic film cartridge which has solved white powder generation problem by devising the Rockwell hardness, a blend of lubricants, a blend of polypropylene resins or a combination of a particular resin composition and groove formation. While, moistureproofness can be improved by thickening the gate mark portion.

  用于摄影胶卷盒的容器体，通过设计洛氏硬度、混合润滑剂、混合聚丙烯树脂或特定树脂成分与凹槽形成的组合，解决了白粉产生的问题。同时，还可以通过加厚栅标部分来提高防潮性能。
• Compositions stabilisées de polyacétals et procédé pour leur fabrication
  申请人：SOLVAY

  公开号：EP0421973A1

  公开（公告）日：1991-04-10

  L'invention concerne une composition stabilisée de poly­acétals comprenant un anti-oxydant phénolique, un copolymère d'éthylène et d'alcool vinylique et un amide aliphatique. L'invention concerne également un procédé de fabrication de cette composition.

  本发明涉及一种由酚类抗氧化剂、乙烯和乙烯醇的共聚物以及脂肪族酰胺组成的聚缩醛稳定组合物。 本发明还涉及一种制造这种组合物的工艺。

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