2-Isopropyl-3,3,5,5-tetramethyl-hexanoic acid | 60468-68-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-Isopropyl-3,3,5,5-tetramethyl-hexanoic acid
• 英文别名: 3,3,5,5-Tetramethyl-2-isopropylcaproic acid；3,3,5,5-tetramethyl-2-propan-2-ylhexanoic acid
• CAS: 60468-68-0
• 化学式: C₁₃H₂₆O₂
• 分子量: 214.348
• InChiKey: KZQJTPQFVHJPCU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  异辛烯 在 propionic acid ; compound with boron fluoride 作用下， 反应 2.0h， 生成 2-Isopropyl-3,3,5,5-tetramethyl-hexanoic acid
  参考文献：
  名称：

  Carbonylation of isobutylene, its oligomers, and N-olefins by carbon monoxide in the presence of BF3 complexes with propionic, acetic or chloroacetic acids

  摘要：

  DOI：

  10.1007/bf00920819

文献信息

• MICELLE COMPOSITION OF POLYMER AND PASSENGER DRUG
  申请人：Kwon Glen S.

  公开号：US20120309780A1

  公开（公告）日：2012-12-06

  Hydrophobic drugs become more practical for treatments by being encapsulated in micelle compositions for increasing solubility. Micelle compositions may include an excipient tocopherol and/or prodrug formulations of the drug. Micelles extend the time period the drug remains in the micelles to improve drug circulation time and thereby drug delivery. Hydrophobic drugs for micelle encapsulation may include rapamycin, geldanamycin, and paclitaxel. Administration of these micelle compositions does not require Cremophor EL or Tween 80, avoiding serious side effects associated with these products which would previously accompany such drug administration.
• US9107814B2
  申请人：——

  公开号：US9107814B2

  公开（公告）日：2015-08-18
• Carbonylation of isobutylene, its oligomers, and N-olefins by carbon monoxide in the presence of BF3 complexes with propionic, acetic or chloroacetic acids
  作者：S. D. Pirozhkov、K. V. Puzitskii、T. N. Myshenkova、K. G. Ryabova、Ya. T. �idus

  DOI：10.1007/bf00920819

  日期：1976.7