Methyl 3-(2,2-difluoroethylamino)pyrazine-2-carboxylate | 1335044-82-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: Methyl 3-(2,2-difluoroethylamino)pyrazine-2-carboxylate
• 英文别名: methyl 3-(2,2-difluoroethylamino)pyrazine-2-carboxylate
• CAS: 1335044-82-0
• 化学式: C₈H₉F₂N₃O₂
• 分子量: 217.175
• InChiKey: AGIOZQVMVOVFKZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  64.1
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  [5-Chloro-3-morpholin-4-yl-2-(trifluoromethyl)phenyl]methanesulfonyl chloride 、 Methyl 3-(2,2-difluoroethylamino)pyrazine-2-carboxylate 在 lithium hexamethyldisilazane 作用下， 以 四氢呋喃 为溶剂， 反应 2.0h， 以54%的产率得到3-[5-chloro-3-morpholino-2-(trifluoromethyl)phenyl]-1-(2,2-difluoroethyl)-2,2-dioxopyrazino[2,3-c]thiazin-4-ol
  参考文献：
  名称：

  [EN] PYRAZINOTHIAZINES HAVING HERBICIDAL ACTION
  [FR] PYRAZINOTHIAZINES À ACTION HERBICIDE

  摘要：

  将公式I中定义的变量的吡啶嗪替代物，用于制备公式I化合物及其N氧化物的过程和中间体，它们的农业上有用的盐，包含它们的组合物以及它们作为除草剂的用途，以及一种控制不受欢迎植被的方法。

  公开号：

  WO2011117151A1

文献信息

• [EN] SUBSTITUTED PYRIDAZINES HAVING HERBICIDAL ACTION<br/>[FR] PYRIDAZINES SUBSTITUÉES À EFFET HERBICIDE
  申请人：BASF SE

  公开号：WO2011117273A1

  公开（公告）日：2011-09-29

  Substituted pyridazines of the formula (I) in which the variables are defined according to the description, processes and intermediates for preparing the compounds of the formula (I) and their N-oxides, their agriculturally suitable salts, compositions comprising them and their use as herbicides, and also methods for controlling unwanted vegetation.

  将公式（I）中定义的变量的吡啶并置物翻译成中文，包括根据描述定义的过程和中间体，用于制备公式（I）化合物及其N-氧化物，适用于农业的盐，包含它们的组合物以及它们作为除草剂的用途，以及控制不受欢迎植被的方法。
• Pyrazinothiazines Having Herbicidal Action
  申请人：Song Dschun

  公开号：US20130012388A1

  公开（公告）日：2013-01-10

  Substituted pyridazines of the formula I in which the variables are defined according to the description, processes and intermediates for preparing the compounds of the formula I and their N oxides, their agriculturally useful salts, compositions comprising them and their use as herbicides, and also a method for controlling unwanted vegetation.

  本发明涉及公式I中变量根据说明定义的取代吡啶并咪唑，制备公式I化合物及其N氧化物的过程和中间体，其在农业上有用的盐，包含它们的组合物以及它们作为除草剂的用途，还涉及一种控制不良植被的方法。
• Substituted Pyridazines Having Herbicidal Action
  申请人：Song Dschun

  公开号：US20130005576A1

  公开（公告）日：2013-01-03

  Substituted pyridazines of the formula I in which the variables are defined according to the description, processes and intermediates for preparing the compounds of the formula I and their N-oxides, their agriculturally suitable salts, compositions comprising them and their use as herbicides, and also methods for controlling unwanted vegetation.
• US8921273B2
  申请人：——

  公开号：US8921273B2

  公开（公告）日：2014-12-30
• [EN] PYRAZINOTHIAZINES HAVING HERBICIDAL ACTION<br/>[FR] PYRAZINOTHIAZINES À ACTION HERBICIDE
  申请人：BASF SE

  公开号：WO2011117151A1

  公开（公告）日：2011-09-29

  Substituted pyridazines of the formula I in which the variables are defined according to the description, processes and intermediates for preparing the compounds of the formula I and their N oxides, their agriculturally useful salts, compositions comprising them and their use as herbicides, and also a method for controlling unwanted vegetation.

  将公式I中定义的变量的吡啶嗪替代物，用于制备公式I化合物及其N氧化物的过程和中间体，它们的农业上有用的盐，包含它们的组合物以及它们作为除草剂的用途，以及一种控制不受欢迎植被的方法。