(2-amino-phenyl)-(4-amino-phenyl)-amine | 4907-43-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (2-amino-phenyl)-(4-amino-phenyl)-amine
• 英文别名: 2.4'-Diamino-diphenylamin；N-(4-aminophenyl)benzene-1,2-diamine；2-N-(4-aminophenyl)benzene-1,2-diamine
• CAS: 4907-43-1
• 化学式: C₁₂H₁₃N₃
• 分子量: 199.255
• InChiKey: DDLOISMWPUUWPL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  64.1
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  (2-amino-phenyl)-(4-amino-phenyl)-amine 在 potassium dichromate 、 溶剂黄146 作用下， 生成 2-氨基吩嗪
  参考文献：
  名称：

  Hewitt; Newman; Winmill, Journal of the Chemical Society, 1909, vol. 95, p. 583

  摘要：

  DOI：
• 作为产物：
  描述：

  2,4'-二硝二苯胺 在 盐酸 、 tin(ll) chloride 作用下， 生成 (2-amino-phenyl)-(4-amino-phenyl)-amine
  参考文献：
  名称：

  Kehrmann; Ott, Chemische Berichte, 1901, vol. 34, p. 3096

  摘要：

  DOI：

文献信息

• 3,4-Dihydro-3-oxopyrido[2,3-b]-pyrazines, compositions and use thereof
  申请人：Fisons Limited

  公开号：US04296114A1

  公开（公告）日：1981-10-20

  There are described compounds of formula I, ##STR1## in which R.sub.1 is phenyl substituted by halogen, alkoxy, alkyl, carboxy-alkyl, --NR.sub.4 R.sub.5, carboxy or alkoxy carbonyl, R.sub.3 is hydrogen, alkyl, mono- or di-carboxy alkyl, halo, alkoxy, phenyl, halo-phenyl, hydroxy, phenoxy, thiol, thioalkoxy, thiophenoxy, --NR.sub.4 R.sub.5, cyano, --COOH, carboxyureido, --CF.sub.3, --COR.sub.6, hydroxyalkyl, aminoalkyl, or alkoxy substituted by NR.sub.4 R.sub.5, ring A is a benzene or a pyridine ring which optionally carries up to 4 substituents R.sub.3, which may be the same or different, R.sub.4 and R.sub.5, which may be the same or different, each represent hydrogen, phenyl, halophenyl or alkyl, the alkyl optionally being substituted by alkoxy or by a mono- or di-alkyl or unsubstituted amino group; or R.sub.4 and R.sub.5, together with the nitrogen atom to which they are attached, form a piperidine, morpholine or an optionally alkyl substituted piperazine ring, and R.sub.6 is hydrogen or alkyl, provided that (i) when R.sub.1 is phenyl substituted by chlorine or bromine, ring A is not a benzene ring substituted by chlorine or bromine, or (ii) when R.sub.1 is phenyl substituted by methoxy R.sub.3 is not phenyl, and pharmaceutically acceptable salts, esters and amides thereof. There are also described methods for making the compounds and pharmaceutical, e.g. anti-inflammatory, compositions containing the compounds.

  描述了式I的化合物，其中R.sub.1是被卤素、烷氧基、烷基、羧基烷基、--NR.sub.4 R.sub.5、羧基或烷氧基羰基取代的苯基，R.sub.3是氢、烷基、单或双羧基烷基、卤素、烷氧基、苯基、卤代苯基、羟基、苯氧基、硫醇、硫代烷氧基、硫代苯氧基、--NR.sub.4 R.sub.5、氰基、--COOH、羧基脲基、--CF.sub.3、--COR.sub.6、羟基烷基、氨基烷基，或被NR.sub.4 R.sub.5取代的烷氧基，环A是苯环或吡啶环，可选地带有多达4个取代基R.sub.3，这些取代基可以相同也可以不同，R.sub.4和R.sub.5，可以相同也可以不同，每个代表氢、苯基、卤代苯基或烷基，其中烷基可选地被烷氧基、单烷基或双烷基或未取代氨基取代；或R.sub.4和R.sub.5，连同它们连接的氮原子，形成哌啶、吗啡或可选地烷基取代的哌嗪环，R.sub.6是氢或烷基，但是当R.sub.1是被氯或溴取代的苯基时，环A不是被氯或溴取代的苯环，或者当R.sub.1是被甲氧基取代的苯基时，R.sub.3不是苯基，以及药学上可接受的盐、酯和酰胺。还描述了制备这些化合物的方法和含有这些化合物的药物，例如抗炎药物。
• Pyridopyrazine and quinoxaline derivatives, processes for their preparation, and pharmaceutical compositions containing them
  申请人：FISONS plc

  公开号：EP0008864A1

  公开（公告）日：1980-03-19

  There are described compounds of formula I, in which R1 is phenyl substituted by halogen, alkoxy, alkyl, carboxy-alkyl, -NR4R5, carboxy or alkoxy carbonyl, R3 is hydrogen, alkyl, mono- or di-carboxy alkyl, halo, alkoxy, phenyl, halo-phenyl, hydroxy, phenoxy, thiol, thioalkoxy, thiophenoxy, -NR4Rs, cyano, -COOH, carboxyureido, -CF3, -CORe, hydroxyalkyl, aminoalkyl, or alkoxy substituted by NR4R5, ring A is a benzene or a pyridine ring which optionally carries up to 4 substituents R3, which may be the same or different, R4 and Rs, which may be the same or different, each represent hydrogen, phenyl, halophenyl or alkyl, the alkyl optionally being substituted by alkoxy or by a mono- or di- alkyl or unsubstituted amino group; or R4 and Rs, together with the nitrogen atom to which they are attached, form a piperidine, morpholine or an optionally alkyl substitued piperazine ring, and R6 is hydrogen or alkyl, provided that (i) when R, is phenyl substituted by chlorine or bromine, ring A is not a benzene ring substituted by chlorine or bromine, or (ii) when R, is phenyl substituted by methoxy R3 is not phenyl, and pharmaceutically acceptable salts, esters and amides thereof. There are also described methods for making the compounds and pharmaceutical, e.g. anti-inflammatory, compositions containing the compounds.

  所述化合物为式 I、 其中 R1 是被卤素、烷氧基、烷基、羧基、-NR4R5、羧基或烷氧基羰基取代的苯基、 R3 是氢、烷基、一羧基或二羧基烷基、卤素、烷氧基、苯基、卤代苯基、羟基、苯氧基、硫醇、硫代烷氧基、噻吩氧基、-NR4Rs、氰基、-COOH、羧基脲基、-CF3、-CORe、羟基烷基、氨基烷基或被 NR4R5 取代的烷氧基、 环 A 是苯环或吡啶环，可选择带有最多 4 个取代基 R3，它们可以相同或不同、 R4和Rs（可以相同或不同）各自代表氢、苯基、卤代苯基或烷基，烷基可选择被烷氧基或单烷基或二烷基或未取代的氨基取代；或R4和Rs与它们所连接的氮原子一起形成哌啶、吗啉或可选择被烷基取代的哌嗪环，以及 R6 为氢或烷基、 但 (i) 当 R 为被氯或溴取代的苯基时，环 A 不是被氯或溴取代的苯环，或 (ii) 当 R 为被甲氧基取代的苯基时，R3 不是苯基、 及其药学上可接受的盐、酯和酰胺。 此外，还介绍了制造这些化合物的方法以及含有这些化合物的药物组合物，例如消炎组合物。
• CARBON BLACK
  申请人：KONICA MINOLTA BUSINESS TECHNOLOGIES, INC.

  公开号：EP1887049A1

  公开（公告）日：2008-02-13

  Carbon black of the present invention has a number average particle size of Feret's diameter of 5 to 300 nm and contains primary particles of 5% or more on a number basis.

  本发明的炭黑具有 5 至 300 纳米的费雷特直径数均粒径，并含有 5%或更多的原生颗粒。
• CARBON BLACK LOADED COMPOSITION, COLORANT COMPOSITION AND CONDUCTIVE COMPOSITION
  申请人：KONICA MINOLTA BUSINESS TECHNOLOGIES, INC.

  公开号：EP1897916A1

  公开（公告）日：2008-03-12

  The present invention provides to a composition, a composition for coloring and a conductive composition, each of which contains new carbon black having a specific number average particle size of Feret's diameter. The present invention relates to a composition containing carbon black, in which a number average particle size of Feret's diameter is 5 to 300 nm and primary particles are contained at 5% or more on a number basis. The composition of the present invention is uniform in coloring and conductivity and makes it possible to be uniform in coloring and conductivity of final forms using those compositions.

  本发明提供了一种组合物、一种着色用组合物和一种导电组合物，其中每种组合物都含有具有特定费雷特直径数平均粒径的新炭黑。 本发明涉及一种含有炭黑的组合物，其中费氏直径的数均粒径为 5 至 300 纳米，原生颗粒的含量为 5%或以上。 本发明的组合物具有均匀的着色和导电性，使得使用这些组合物的最终产品具有均匀的着色和导电性。
• BLACK RESIN COMPOSITION, RESIN BLACK MATRIX, COLOR FILTER AND LIQUID CRYSTAL DISPLAY
  申请人：Toray Industries, Inc.

  公开号：EP2135900A1

  公开（公告）日：2009-12-23

  A black resin composition capable of forming a black matrix having high OD value and high adhesion as well as high resistance is disclosed. The black resin composition is a black resin composition comprising at least a light shielding agent, a resin and a solvent, which light shielding agent contains at least titanium nitride compound particles, wherein the angle of diffraction 20 of the peak originated from (200) plane of the titanium nitride compound particles when CuKα line is used as the X-ray source is not less than 42.5° and not more than 42.8°. Using this black resin composition allows a thin resin black matrix having a high light shielding property and high resistance to be readily attained.

  本发明公开了一种黑色树脂组合物，该组合物能够形成具有高外径值、高附着力和高电阻的黑色基体。该黑色树脂组合物是一种黑色树脂组合物，至少包含一种光屏蔽剂、一种树脂和一种溶剂，该光屏蔽剂至少包含氮化钛化合物颗粒，其中，当使用 CuKα 线作为 X 射线源时，源于氮化钛化合物颗粒（200）平面的峰值的衍射角 20 不小于 42.5°，也不大于 42.8°。使用这种黑色树脂组合物很容易获得具有高遮光性能和高电阻的黑色薄树脂基体。