| 18777-30-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• CAS: 18777-30-5
• 化学式: C10H19NNaO3
• 分子量: 224.25
• InChiKey: ZBFRXRLPWMWBEY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.17
• 重原子数：
  15
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  66.4
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• High-absorbable transvaginal preparation containing biologically active peptides
  申请人：TEIKOKU SEIYAKU KABUSHIKI KAISHA

  公开号：EP0418642A1

  公开（公告）日：1991-03-27

  A high-absorbable transvaginal preparation having excellent absorbability of the active ingredient, which comprises a biologically active polypeptide and an absorption promoter comprising a polyoxyethylenealkylphenyl ether and one or more compounds selected from the group consisting of an N-acylamino acid, cholic acids, pectic acid, taurine, saccharin, glycyrrhizic acid, aspartame, or a salt thereof.

  一种高吸收性经阴道制剂，其活性成分具有极佳的可吸收性，该制剂由生物活性多肽和吸收促进剂组成，吸收促进剂包括聚氧乙烯烷基苯基醚和一种或多种选自 N-酰基氨基酸、胆酸、果胶酸、牛磺酸、糖精、甘草酸、阿斯巴甜或其盐类的化合物。
• EP2908845A1
  申请人：——

  公开号：EP2908845A1

  公开（公告）日：2015-08-26
• Fatty Acid Acylated Amino Acids for Growth Hormone Delivery
  申请人：Novo Nordisk Health Care AG

  公开号：US20150250882A1

  公开（公告）日：2015-09-10

  The present invention relates to growth hormone compositions comprising a fatty acid acylated amino acids (FA-aa's), which may be used in pharmaceutical compositions such as pharmaceutical compositions for oral administration of growth hormone.
• [EN] FATTY ACID ACYLATED AMINO ACIDS FOR GROWTH HORMONE DELIVERY<br/>[FR] ACIDES AMINÉS ACYLÉS PAR UN ACIDE GRAS POUR L'ADMINISTRATION D'HORMONE DE CROISSANCE
  申请人：NOVO NORDISK HEALTHCARE AG

  公开号：WO2014060512A1

  公开（公告）日：2014-04-24

  The present invention relates to growth hormone compositions comprising a fatty acid acylated amino acids (FA-aa's), which may be used in pharmaceutical compositions such as pharmaceutical compositions for oral administration of growth hormone.