3,3-Ethylenedioxy-1-p-toluenesulfonate | 15658-19-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3,3-Ethylenedioxy-1-p-toluenesulfonate
• 英文别名: 2-(2-Methyl-1,3-dioxolan-2-yl)ethyl 4-methylbenzenesulfonate
• CAS: 15658-19-2
• 化学式: C₁₃H₁₈O₅S
• 分子量: 286.349
• InChiKey: QMFMRPYBMIYCQT-UHFFFAOYSA-N

物化性质

• 沸点：
  407.6±25.0 °C(Predicted)
• 密度：
  1?+-.0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  19
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  70.2
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  3,3-Ethylenedioxy-1-p-toluenesulfonate 在 lithium bromide 作用下， 以 丙酮 为溶剂， 反应 3.0h， 生成 2-(2-溴乙基)-2-甲基-1,3-二恶茂烷
  参考文献：
  名称：

  Sokolov; Salfetnikova; Potekhin, Russian Journal of Organic Chemistry, 1996, vol. 32, # 6, p. 838 - 846

  摘要：

  DOI：
• 作为产物：
  描述：

  methyl (2-methyl-1,3-dioxolan-2-yl)acetate 在 吡啶 、 lithium aluminium tetrahydride 作用下， 以 四氢呋喃 为溶剂， 反应 18.0h， 生成 3,3-Ethylenedioxy-1-p-toluenesulfonate
  参考文献：
  名称：

  Potentiation of cADPR-Induced Ca²⁺-Release by Methylxanthine Analogues

  摘要：

  Caffeine and other methylxanthines are known to induce Ca2+-release from intracellular stores via the ryanodine receptor. In the present work, a range of caffeine analogues, in which methyl groups at the 1 and 7 positions were replaced with alkyl chains containing different functional groups (oxo, hydroxyl, propargyl, ester, and acids), were synthesized. These compounds were then screened for their ability to potentiate Ca2+-release induced by cADPR (an endogenous modulator of ryanodine receptors) in sea urchin egg homogenates. Two of the synthesized methylxanthines, 1,3-dimethyl-7-(7-hydroxyoctyl)xanthine (37) and 3-methyl-7-(7-oxooctyl)-1-propargylxanthine (66), were shown to be more potent than caffeine in potentiating cADPR-induced Ca2+-release, while 1,3-dimethyl-7-(5-ethylcarboxypentyl)xanthine (14) was shown to be more efficacious. The development of new methylxanthine analogues may lead to a better understanding of ryanodine receptor function and could possibly provide novel therapeutic agents.

  DOI：

  10.1021/jm980469t

文献信息

• CYCLIC COMPOUND, PHOTORESIST BASE MATERIAL AND PHOTORESIST COMPOSITION
  申请人：Shibata Mitsuru

  公开号：US20100190107A1

  公开（公告）日：2010-07-29

  A cyclic compound shown by the following formula (I):

  一个由以下公式（I）所示的环状化合物：
• CALIXRESORCINARENE COMPOUND, PHOTORESIST BASE COMPRISING THE SAME, AND COMPOSITION THEREOF
  申请人：Watanabe, Takeo

  公开号：EP1886989A1

  公开（公告）日：2008-02-13

  A calixresorcinarene compound represented by the following formula (1): wherein eight Rs are n (n is an integer of 1 to 7) substituents that are one or more types of substituents selected from groups represented by the following formula (2), and m (m is an integer shown by 8-n) hydrogen atoms; and R's, which may be the same or different, are each a straight-chain aliphatic hydrocarbon group having 2 to 12 carbon atoms, a branched aliphatic hydrocarbon group having 3 to 12 carbon atoms, a phenyl group, a p-phenylphenyl group, a p-tert-butylphenyl group, and an aromatic group represented by the following formula (3), or a substituent formed by combining two or more of these substituents: wherein R" is a hydrogen atom or a substituent selected from the substituents represented by the formula (2).

  以下是一个由下式（1）表示的calixresorcinarene化合物： 其中，八个Rs是n（n是1到7的整数）取代基，是从以下式（2）所代表的基团中选择的一种或多种类型的取代基，m（m是8-n所示的整数）个氢原子；而R'可以相同也可以不同，每个都是具有2到12个碳原子的直链脂肪烃基，具有3到12个碳原子的支链脂肪烃基，苯基，p-苯基苯基，p-叔丁基苯基和由以下式（3）所代表的芳基或两个或更多这些取代基组合形成的取代基： 其中，R"是氢原子或从式（2）所代表的取代基中选择的取代基。
• Approaches to the Synthesis of Triterpenoids. II. Some Tetracyclic Precursors Suitable for Conversion into Pentacyclic Triterpenoids
  作者：J. W. ApSimon、P. Baker、J. Buccini、J. W. Hooper、S. Macaulay

  DOI：10.1139/v72-309

  日期：1972.6.15

  The stereoselective total synthesis of several partially reduced chrysene derivatives, suitable as precursors for a variety of triterpenoids, is described. The key reaction in the most efficient route involves the highly stereoselective reductive alkylation of a cyclic α,β-unsaturated ketone with allyl bromide in lithium–ammonia, using water as a proton donor.

  描述了几种部分还原的 chrysene 衍生物的立体选择性全合成，这些衍生物适合作为各种三萜类化合物的前体。最有效路线中的关键反应涉及使用水作为质子供体，在锂 - 氨中使用烯丙基溴对环状 α,β-不饱和酮进行高度立体选择性的还原烷基化。
• ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE COMPOSITION, AND RESIST FILM, RESIST-COATED MASK BLANKS, RESIST PATTERN FORMING METHOD AND PHOTOMASK EACH USING THE COMPOSITION
  申请人：FUJIFILM CORPORATION

  公开号：US20150010855A1

  公开（公告）日：2015-01-08

  There is provided an actinic ray-sensitive or radiation-sensitive composition containing (α) a compound represented by the formula (αI) capable of generating an acid having a size of 200 Å 3 or more in volume and (β) a compound capable of generating an acid upon irradiation with an actinic ray or radiation, and the formula (αI) is defined as herein, and a resist film formed using the actinic ray-sensitive or radiation-sensitive composition, a resist-coated mask blanks coated with the resist film, a resist pattern forming method comprising exposing the resist film and developing the exposed film, a photomask obtained by exposing and developing the resist-coated mask blanks, a method for manufacturing an electronic device, comprising the resist pattern forming method and an electronic device manufactured by the manufacturing method of an electronic device.

  提供一种感光或辐射敏感的组合物，其中包含(α)一种化合物，其由公式(αI)表示，能够产生大小为200Å3或更大的体积的酸，以及(β)一种化合物，能够在受到光辐射或辐射时产生酸，公式(αI)的定义如本文所述。还提供了使用该感光或辐射敏感组合物形成的光阻膜，涂有光阻膜的光阻涂层掩模坯料，包括曝光光阻膜和显影曝光后膜的光阻图案形成方法，通过曝光和显影涂有光阻涂层的掩模坯料获得的光掩模，以及一种电子器件的制造方法，包括光阻图案形成方法和制造电子器件的电子器件制造方法，以及通过该电子器件制造方法制造的电子器件。
• Keinan, Ehud; Sinha, Subhash C.; Sinha-Bagchi, Anjana, Journal of the Chemical Society. Perkin transactions I, 1991, # 12, p. 3333 - 3340
  作者：Keinan, Ehud、Sinha, Subhash C.、Sinha-Bagchi, Anjana

  DOI：——

  日期：——