4-(4-nitro-benzylidenamino)-benzoic acid methyl ester | 16979-16-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(4-nitro-benzylidenamino)-benzoic acid methyl ester
• 英文别名: 4-(4-Nitro-benzylidenamino)-benzoesaeure-methylester；Methyl-p-nitrobenzylidene-p-aminobenzoat；(E)-methyl 4-(4-nitrobenzylideneamino)benzoate；methyl 4-[(4-nitrophenyl)methylideneamino]benzoate
• CAS: 16979-16-1
• 化学式: C₁₅H₁₂N₂O₄
• 分子量: 284.271
• InChiKey: KGELAANLLIAOIX-UHFFFAOYSA-N

物化性质

• 熔点：
  216-216.5 °C
• 沸点：
  463.7±30.0 °C(Predicted)
• 密度：
  1.23±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  84.5
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  4-(4-nitro-benzylidenamino)-benzoic acid methyl ester 在 盐酸 作用下， 以 乙醇 为溶剂， 生成 4-氨基苯甲酸甲酯
  参考文献：
  名称：

  Reaction of antipyrine with Schiff bases

  摘要：

  New dihydropyrazolone derivatives were prepared by condensation of antipyrine with substituted arylmethyleneanilines or arylmethylene-2-naphthylamines.

  DOI：

  10.1134/s107036320602023x
• 作为产物：
  描述：

  对硝基苯甲醛 、 4-氨基苯甲酸甲酯 在 溶剂黄146 作用下， 生成 4-(4-nitro-benzylidenamino)-benzoic acid methyl ester
  参考文献：
  名称：

  Bamberger; Elger, Justus Liebigs Annalen der Chemie, 1929, vol. 475, p. 295

  摘要：

  DOI：

文献信息

• Nickel Catalyzed Imine Aldol Reactions between Activated Imines and Pronucleophiles
  作者：N Shida

  DOI：10.1016/00404-0399(50)0912v-

  日期：1995.7.10

  Treatment of activated imines 1 with carbonyl compounds 2 in the presence of catalytic amounts of NiCl2(PPh(3))(2) or NiBr2(PPh(3))(2) at room temperature affords imine aldol products 3 in high to good yields.
• Synthesis of 4-[(p-alkylanilino-p-alkylphenyl)methyl]-4-butyl-1,2-diphenylpyrazolidine-3,5-diones
  作者：N. G. Kozlov、S. V. Rubis、A. V. Tkachev、L. I. Basalaeva

  DOI：10.1134/s1070363206020241

  日期：2006.2

  4-Butyl-1,2-diphenylpyrazolidine-3,5-dione derivatives were prepared by its condensation with Schiff bases formed from p-aminobenzoic acid and its methyl and ethyl esters as amine components and substituted aromatic aldehydes.
• Catalytic reactions of bis-π-allylpalladium generated from allyltrifluoroborate
  作者：Hiroyuki Nakamura、Kazuki Shimizu

  DOI：10.1016/j.tetlet.2010.11.082

  日期：2011.1

  Bis-pi-allylpalladium-catalyzed nucleophilic allylations to aldehydes 2 and imines 3 have been achieved by replacing allylstannanes with allyltrifluoroborate. Amphiphilic bisallylation of activated olefins 6 with allyltrifluoroborate and allyl acetate also proceeded smoothly in the presence of Pd(2)(dba)(3)center dot CHCl(3) and tricyclohexylphosphine catalysts. (C) 2010 Elsevier Ltd. All rights reserved.
• Reaction of antipyrine with Schiff bases
  作者：N. G. Kozlov、L. I. Basalaeva

  DOI：10.1134/s107036320602023x

  日期：2006.2

  New dihydropyrazolone derivatives were prepared by condensation of antipyrine with substituted arylmethyleneanilines or arylmethylene-2-naphthylamines.
• Bamberger; Elger, Justus Liebigs Annalen der Chemie, 1929, vol. 475, p. 295
  作者：Bamberger、Elger

  DOI：——

  日期：——