3,3,4,4,5,5,6,6,7,7,8,8,8,9,10,10,10,10-heptadecafluoro-1-decathioacetic acid | 54207-61-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 3,3,4,4,5,5,6,6,7,7,8,8,8,9,10,10,10,10-heptadecafluoro-1-decathioacetic acid
• 英文别名: [(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-Heptadecafluorodecyl)thio]acetic acid；2-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecylsulfanyl)acetic acid
• CAS: 54207-61-3
• 化学式: C₁₂H₇F₁₇O₂S
• 分子量: 538.225
• InChiKey: XUSAHPQPYNQVNZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.6
• 重原子数：
  32
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  62.6
• 氢给体数：
  1
• 氢受体数：
  20

反应信息

• 作为反应物：
  描述：

  3,3,4,4,5,5,6,6,7,7,8,8,8,9,10,10,10,10-heptadecafluoro-1-decathioacetic acid 在 potassium hydroxide 作用下， 以 甲醇 为溶剂， 反应 2.0h， 以91%的产率得到Potassium;2-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecylsulfanyl)acetate
  参考文献：
  名称：

  [EN] NEW AMMONIUM SALTS OF FLUORINATED ORGANIC ACIDS, METHOD OF THEIR SYNTHESIS AND APPLICATION
  [FR] NOUVEAUX SELS D'AMMONIUM D'ACIDES ORGANIQUES FLUORÉS, LEUR PROCÉDÉ DE SYNTHÈSE ET LEUR APPLICATION

  摘要：

  公开号：

  WO2020084599A4
• 作为产物：
  描述：

  3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-十七氟-1-癸硫醇 在 氢氧化钾 、 sodium ethanolate 作用下， 以 甲醇 、 乙醇 为溶剂， 反应 19.0h， 生成 3,3,4,4,5,5,6,6,7,7,8,8,8,9,10,10,10,10-heptadecafluoro-1-decathioacetic acid
  参考文献：
  名称：

  Synthèse de nouveaux isocyanates F-alkylés dérivés des 2′-ou 3′-[2-(F-alkyl)éthylthio] alkanoates d'éthyle

  摘要：

  Ethyl 2'- or 3'-[2-(F-alkyl)ethylthio] alkanoates intermediates are prepared by condensation of ethyl bromoalkanoates with 2-(F-alkyl) ethanethiols. These eaters are used as starting material in the synthesis of new F-alkylated isocyanates performed according to the Curtius method.

  DOI：

  10.1016/s0022-1139(98)00205-x

文献信息

• Surface properties of new catanionic semi-fluorinated hybrid surfactants
  作者：Alioune Diouf、Elisabeth Taffin de Givenchy、Samba Yandé Dieng、Abdoulaye Dramé、Sonia Amigoni、Thierry Darmanin、Frédéric Guittard

  DOI：10.1016/j.jfluchem.2014.02.004

  日期：2014.5

  In order to study their aggregation behaviour, a rapid synthetic procedure from perfluoroalkylethyl thiol derivatives led to twenty four original catanionic hybrid surfactants of general formula: [RF(CH2)(2)S(CHQ)(2)CO2-; HN+(CH3)(2)R-H (Q= H or Cl; R-F = C4F9, C6F13, C8F17; R-H = C6H13, C8H17, C10H21, C12H25)]. Critical aggregation concentration (CAC), surface tension at the CAC (gamma s) and free energy of aggregation (Delta G(A)degrees) of the title surfactants, in aqueous solution, have been investigated as a function of the number of carbon atoms in both the fluorinated and the hydrocarbon tails. TEM studies were used to estimate the shape and size of the aggregates and confirmed the general tendency of fluorinated surfactants to form aggregates with lesser curvature. These catanionic surfactants exhibited very low surface tension at critical aggregation concentration (CAC) of 15.3-17.4 mN m(-1) as well as low CAC of 3 x 10(-5)-11 x 10(-3) and the substitution of one hydrogen atom by one chlorine atom didn't affect significantly the aggregation phenomenon. (C) 2014 Elsevier B.V. All rights reserved.
• New Ammonium Salts Of Fluorinated Organic Acids, Method Of Their Synthesis and Application
  申请人：Nanosanguis

  公开号：US20210369846A1

  公开（公告）日：2021-12-02

  The exemplary arrangements relate to ammonium salts of partially fluorinated organic acids. The exemplary arrangements also relate to methods of synthesis of the ammonium salts of partially fluorinated organic acids. The exemplary arrangements also relate to methods of use of the ammonium salts of partially fluorinated organic acids to produce stabilizing emulsions of the oil-in-water and/or water-in-oil type. The exemplary arrangements also relate to methods of use and applications of the ammonium salts of partially fluorinated organic acids, for example use as stabilizing agents in blood substitute preparations.
• [EN] NEW AMMONIUM SALTS OF FLUORINATED ORGANIC ACIDS, METHOD OF THEIR SYNTHESIS AND APPLICATION<br/>[FR] NOUVEAUX SELS D'AMMONIUM D'ACIDES ORGANIQUES FLUORÉS, LEUR PROCÉDÉ DE SYNTHÈSE ET LEUR APPLICATION
  申请人：NANOSANGUIS

  公开号：WO2020084599A4

  公开（公告）日：2020-10-08
• Synthèse de nouveaux isocyanates F-alkylés dérivés des 2′-ou 3′-[2-(F-alkyl)éthylthio] alkanoates d'éthyle
  作者：M.A. Jouani、F. Le Duff、S. Szönyi、A. Cambon

  DOI：10.1016/s0022-1139(98)00205-x

  日期：1998.10

  Ethyl 2'- or 3'-[2-(F-alkyl)ethylthio] alkanoates intermediates are prepared by condensation of ethyl bromoalkanoates with 2-(F-alkyl) ethanethiols. These eaters are used as starting material in the synthesis of new F-alkylated isocyanates performed according to the Curtius method.