prop-2-enyl (2R,5S)-5-(phenylmethoxyamino)-1-(2,2,2-trifluoroacetyl)piperidine-2-carboxylate | 396731-10-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: prop-2-enyl (2R,5S)-5-(phenylmethoxyamino)-1-(2,2,2-trifluoroacetyl)piperidine-2-carboxylate
• CAS: 396731-10-5
• 化学式: C₁₈H₂₁F₃N₂O₄
• 分子量: 386.4
• InChiKey: ZLLSQQALSFHMJQ-LSDHHAIUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  27
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  67.9
• 氢给体数：
  1
• 氢受体数：
  8

文献信息

• Azabicyclic compounds, preparation thereof and use as medicines, in particular as antibacterial agents
  申请人：——

  公开号：US20030199541A1

  公开（公告）日：2003-10-23

  The invention relates to new heterocyclic compounds of general formula (I), and their salts with a base or an acid: 1 The invention also relates to a process for the preparation of these compounds as well as their use as medicaments, in particular as anti-bacterial agents.

  该发明涉及一般式（I）的新杂环化合物及其与碱或酸形成的盐：该发明还涉及制备这些化合物的方法以及它们作为药物的用途，特别是作为抗菌剂。
• New heterocyclic compounds, their preparation and their use as medicaments, in particular as anti-bacterial agents
  申请人：Lampilas Maxime

  公开号：US20060189652A1

  公开（公告）日：2006-08-24

  The invention relates to new heterocyclic compounds of general formula (I), and their salts with a base or an acid: The invention also relates to a process for the preparation of these compounds as well as their use as medicaments, in particular as anti-bacterial agents.

  该发明涉及一种新的杂环化合物，其一般式为(I)，以及它们与碱或酸的盐：该发明还涉及一种制备这些化合物的方法，以及它们作为药物的用途，特别是作为抗菌剂。
• Heterocyclic compounds, their preparation and their use as medicaments, in particular as anti-bacterial agents
  申请人：Lampilas Maxime

  公开号：US20060046995A1

  公开（公告）日：2006-03-02

  The invention relates to new heterocyclic compounds of general formula (I), and their salts with a base or an acid: The invention also relates to a process for the preparation of these compounds as well as their use as medicaments, in particular as anti-bacterial agents.

  本发明涉及一种通式（I）的新的杂环化合物及其与碱或酸的盐：本发明还涉及制备这些化合物的方法以及它们作为药物的用途，特别是作为抗菌剂。
• US7112592B2
  申请人：——

  公开号：US7112592B2

  公开（公告）日：2006-09-26
• US7638529B2
  申请人：——

  公开号：US7638529B2

  公开（公告）日：2009-12-29