N'-cyclopentylidene-2-hydroxybenzohydrazide | 100135-10-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N'-cyclopentylidene-2-hydroxybenzohydrazide
• 英文别名: N-cyclopentylidene-2-hydroxybenzohydrazide；N-(cyclopentylideneamino)-2-hydroxybenzamide
• CAS: 100135-10-2
• 化学式: C₁₂H₁₄N₂O₂
• mdl: MFCD00160920
• 分子量: 218.255
• InChiKey: IHEMBCPCLDZDBM-UHFFFAOYSA-N

物化性质

• 密度：
  1.26±0.1 g/cm3(Predicted)
• 溶解度：
  24.8 [ug/mL]

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.333
• 拓扑面积：
  61.7
• 氢给体数：
  2
• 氢受体数：
  3

安全信息

• 海关编码：
  2928000090

反应信息

• 作为反应物：
  描述：

  N'-cyclopentylidene-2-hydroxybenzohydrazide 、 三氯化铁 在 sodium acetate 作用下， 以 甲醇 为溶剂， 以95%的产率得到[Fe2(N-cyclopentylidene-2-hydroxybenzohydrazinde-1H)4(μ-OCH3)2]
  参考文献：
  名称：

  Stability, molecular structures and magnetic properties of dinuclear iron complexes supported by benzoic hydrazide derivative ligands

  摘要：

  We report experimental evidences including molecular solid-state structure determinations, magnetic measurements and EPR studies for the formation (in the solid-state) of novel dinuclear Fe-2(III)(mu-OMe)(2)(L)(4) complexes (HL are 2-ylidenhydrazidebenzoic-1,3-dithiolane acid and N'-cyclopentylidene-2-hydroxybenzohydrazide). The two novel dinuclear iron compounds described in the present contribution exhibit antiferromagnetic intra-molecular coupling. Crystal structures of the supporting ligands as well as one mononuclear species have also been determined. (C) 2009 Elsevier B. V. All rights reserved.

  DOI：

  10.1016/j.ica.2009.08.027
• 作为产物：
  描述：

  水杨酰肼 、 环戊酮 114.0 ℃ 、190.0 kPa 条件下， 反应 0.08h， 以100%的产率得到N'-cyclopentylidene-2-hydroxybenzohydrazide
  参考文献：
  名称：

  Fast Synthesis of N-Acylhydrazones Employing a Microwave Assisted Neat Protocol

  摘要：

  A variety of N-acylhydrazones were synthesized Under microwave irradiation within 2.5-10 min, starting from benzo, salicyloyl, and isonicotinic hydrazides. The protocol developed employs microwave irradiation in the absence of solvents and catalysts, leading to high yields. The results are reproducible in a 500 mg to 5 g scale.

  DOI：

  10.1021/cc9001444

文献信息

• Spontaneous Reduction of High‐Spin Fe ^III Complexes Supported by Benzoic Hydrazide Derivative Ligands
  作者：Nouri Bouslimani、Nicolas Clément、Clément Toussaint、Sophie Hameury、Philippe Turek、Sylvie Choua、Samuel Dagorne、David Martel、Richard Welter

  DOI：10.1002/ejic.200900382

  日期：2009.9

  herein experimental evidence for the spontaneous reduction of new high-spin iron(III) FeIII(L(n))2Cl, L complexes to new high-spin iron(II) FeII(HL(n))2Cl2 mononuclear complexes. These processes were checked by EPR, cyclovoltammetric, and pseudo-steady voltammetric studies. Crystal structures of three new complexes (one FeIII and two FeII) were obtained from RX single-crystal diffraction.(© Wiley-VCH

  我们在此报告了新的高自旋铁 (III) FeIII(L(n))2Cl、L 配合物自发还原为新的高自旋铁 (II) FeII(HL(n))2Cl2 单核配合物的实验证据。这些过程通过 EPR、循环伏安法和伪稳态伏安法研究进行了检查。从 RX 单晶衍射中获得了三个新配合物（一个 FeIII 和两个 FeII）的晶体结构。 (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
• Fast Synthesis of <i>N</i>-Acylhydrazones Employing a Microwave Assisted Neat Protocol
  作者：Marta M. Andrade、Maria Teresa Barros

  DOI：10.1021/cc9001444

  日期：2010.3.8

  A variety of N-acylhydrazones were synthesized Under microwave irradiation within 2.5-10 min, starting from benzo, salicyloyl, and isonicotinic hydrazides. The protocol developed employs microwave irradiation in the absence of solvents and catalysts, leading to high yields. The results are reproducible in a 500 mg to 5 g scale.
• Stability, molecular structures and magnetic properties of dinuclear iron complexes supported by benzoic hydrazide derivative ligands
  作者：Nouri Bouslimani、Nicolas Clément、Guillaume Rogez、Philippe Turek、Sylvie Choua、Samuel Dagorne、Richard Welter

  DOI：10.1016/j.ica.2009.08.027

  日期：2010.1

  We report experimental evidences including molecular solid-state structure determinations, magnetic measurements and EPR studies for the formation (in the solid-state) of novel dinuclear Fe-2(III)(mu-OMe)(2)(L)(4) complexes (HL are 2-ylidenhydrazidebenzoic-1,3-dithiolane acid and N'-cyclopentylidene-2-hydroxybenzohydrazide). The two novel dinuclear iron compounds described in the present contribution exhibit antiferromagnetic intra-molecular coupling. Crystal structures of the supporting ligands as well as one mononuclear species have also been determined. (C) 2009 Elsevier B. V. All rights reserved.