methyl 2-(2-chloroacetoxy)benzoate | 60504-02-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: methyl 2-(2-chloroacetoxy)benzoate
• 英文别名: Chloressigsaeure-(2-methoxycarbonyl-phenylester)；2-chloroacetoxy-benzoic acid methyl ester；2-Chloracetoxy-benzoesaeure-methylester；Chloracetyl-salicylsaeuremethylester；Methyl 2-[(chloroacetyl)oxy]benzoate；methyl 2-(2-chloroacetyl)oxybenzoate
• CAS: 60504-02-1
• 化学式: C₁₀H₉ClO₄
• 分子量: 228.632
• InChiKey: BOMYQMNIRPEDGO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  methyl 2-(2-chloroacetoxy)benzoate 在 丙酮 、 sodium iodide 作用下， 生成 2-pyrrolidinoacetoxy-benzoic acid methyl ester; hydrochloride
  参考文献：
  名称：

  Reactions in the Salicylic Acid Series. A New Rearrangement of Acylsalicylic Acid Derivatives

  摘要：

  DOI：

  10.1021/ja01517a050
• 作为产物：
  描述：

  氯乙酰氯 、 水杨酸甲酯 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 8.0h， 以56%的产率得到methyl 2-(2-chloroacetoxy)benzoate
  参考文献：
  名称：

  Mali, Raghao S.; Deshpande, Jyoti V., Organic Preparations and Procedures International, 1995, vol. 27, # 6, p. 663 - 667

  摘要：

  DOI：

文献信息

• Hahn; Loos, Chemische Berichte, 1918, vol. 51, p. 1442
  作者：Hahn、Loos

  DOI：——

  日期：——
• Reduction of Substituted Phenyl 2-Chloroacetates at Silver Cathodes: Electrosynthesis of Coumarins
  作者：Erick M. Pasciak、Dennis G. Peters

  DOI：10.1149/2.0551412jes

  日期：——

  To explore the electrosynthesis of coumarins, cyclic voltammetry and controlled-potential (bulk) electrolysis have been employed to investigate the reduction of the carbon-chlorine bond of five substituted phenyl 2-chloroacetates at silver cathodes in dimethylformamide (DMF) containing 0.10 M tetra-n-butylammonium tetrafluoroborate (TBABF(4)) as supporting electrolyte; the five substrates are 2-formylphenyl 2-chloroacetate (1a), 2-acetylphenyl 2-chloroacetate (2a), methyl 2-(2-chloroacetoxy)benzoate (3a), 2-formyl-5-methoxyphenyl 2-chloroacetate (4a), and 2-formyl-3,5-dimethoxyphenyl 2-chloroacetate (5a). We have examined (a) the effects of substituents on the benzene ring of the substrate as well as the nature of the aryl carbonyl moiety on the formation of the coumarin product and (b) the effect of solvent-namely, DMF, acetonitrile (CH3CN), benzonitrile (PhCN), and propylene carbonate (PC)-and substrate concentration on the yield of the coumarin. It was found that the most unsubstituted substrate (1a) afforded the highest yield (41%) of the desired coumarin in a DMF-TBABF(4) medium. A mechanistic scheme is proposed to account for the formation of the coumarin. Furthermore, the only other products seen in these reductions are 2-substituted phenols, which are precursors for synthesis of the various substrates. (C) 2014 The Electrochemical Society. All rights reserved.
• FILM-FORMING POLYMER AND ANTIFOULING PAINT
  申请人：Jotun AS

  公开号：EP1487928A1

  公开（公告）日：2004-12-22
• US4835312A
  申请人：——

  公开号：US4835312A

  公开（公告）日：1989-05-30
• [EN] FILM-FORMING POLYMER AND ANTIFOULING PAINT<br/>[FR] POLYMERE FILMOGENE ET PEINTURE ANTISALISSURE
  申请人：JOTUN AS

  公开号：WO2003080747A1

  公开（公告）日：2003-10-02

  Water insoluble, water erodible, film forming polymer for antifouling paint, which includes repeating units corresponding to the monomers A and B : A) 2-95 mole % of monomers of formula (I), wherein n is an integer from 1 to 4, X is H or CH3, Y is H or an optionally esterified COOH group, R1 is Ph(R2)m, -C(O)R3 or -Si(R4)3, m is an integer from 1 to 3, R2, which are the same or different, are selected from -C(O)H, C(O)R5, COOR6, CH2COOR7, C1-4 alkyl, C1-4 alkanoyl, halogen, nitro, OH and OR8, R3 is selected from substituted or unsubstituted alkyl, aryl, aralkyl and heterocyclyl, R4, which are the same or different, are selected from substituted or unsubstituted C1-20 alkyl, C5-20 aryl, C1-20 alkoxy and C5-20 aryloxy, and R5, R6, R7 and R8 are independently selected from substituted or unsubstituted C1-20 alkyl and C5-20 aryl; and B) 5-98 mole % of other vinyl polymerisable monomers.