4,4-Bis(diphenylphosphanyl)butan-2-one | 1019206-51-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4,4-Bis(diphenylphosphanyl)butan-2-one
• 英文别名: 4,4-bis(diphenylphosphanyl)butan-2-one
• CAS: 1019206-51-9
• 化学式: C₂₈H₂₆OP₂
• 分子量: 440.461
• InChiKey: NZMMWEMEACGUIT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  31
• 可旋转键数：
  8
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  3-丁炔-2-酮 、 二苯基膦 在 三乙胺 盐酸 、 potassium cyanide 作用下， 以 二氯甲烷 为溶剂， 生成 4,4-Bis(diphenylphosphanyl)butan-2-one
  参考文献：
  名称：

  Base controlled (1,1)- and (1,2)-hydrophosphination of functionalized alkynes

  摘要：

  The (1,1)- and (1,2)-addition of diphenylphosphine to 3-butyn-2-one and ethyl propiolate can be controlled chemoselectively by regulating the amount of triethylamine as the external base and in the presence of the chiral organopalladium(II) template derived from (R)-N,N-diniethyl-1-(1-naphthyl)ethylamine. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.01.066

文献信息

• Base controlled (1,1)- and (1,2)-hydrophosphination of functionalized alkynes
  作者：Yi Zhang、Lulu Tang、Yi Ding、Jia-Hui Chua、Yongxin Li、Mingjun Yuan、Pak-Hing Leung

  DOI：10.1016/j.tetlet.2008.01.066

  日期：2008.3

  The (1,1)- and (1,2)-addition of diphenylphosphine to 3-butyn-2-one and ethyl propiolate can be controlled chemoselectively by regulating the amount of triethylamine as the external base and in the presence of the chiral organopalladium(II) template derived from (R)-N,N-diniethyl-1-(1-naphthyl)ethylamine. (c) 2008 Elsevier Ltd. All rights reserved.