glycidyl 4-tolylate | 17002-95-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: glycidyl 4-tolylate
• 英文别名: oxiran-2-ylmethyl 4-methylbenzoate
• CAS: 17002-95-8
• 化学式: C₁₁H₁₂O₃
• 分子量: 192.214
• InChiKey: SJVUKRJWTDCMSJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  38.8
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3,4-二甲氧基苯乙胺 、 glycidyl 4-tolylate 反应 16.0h， 生成 4-Methyl-benzoic acid 3-[2-(3,4-dimethoxy-phenyl)-ethylamino]-2-hydroxy-propyl ester
  参考文献：
  名称：

  [(Arylcarbonyl)oxy]propanolamines. 1. Novel .beta.-blockers with ultrashort duration of action

  摘要：

  Novel [(arylcarbonyl)oxy]propanolamines were synthesized and investigated as potential ultrashort-acting beta-adrenergic receptor blockers. Many of these analogues exhibited good potency and short duration. The N-ureidoalkyl analogue 85 (ACC-9089) has a potency equal to propranolol and a duration of action of about 21 min in the dog. It has been selected as a candidate for further clinical study. Structure-activity relationships and structure-duration relationships for these new beta-blockers are also discussed.

  DOI：

  10.1021/jm00374a013
• 作为产物：
  描述：

  对甲基苯甲酸甲酯 、 缩水甘油 在 三十二烷基甲基氯化铵 作用下， 以 正己烷 为溶剂， 反应 2.0h， 以44%的产率得到glycidyl 4-tolylate
  参考文献：
  名称：

  季烷基烷基铵盐催化的甲基酯的酯交换反应将缩水甘油转化为缩水甘油酯

  摘要：

  缩水甘油的催化转化同时保持其环氧化物部分完整是具有挑战性的，因为通过氢键与羟基相互作用的末端环氧化物对于开环反应是不稳定的。我们发现季烷基铵盐通过甲酯的酯交换反应催化缩水甘油缩水合为缩水甘油酯。所开发的方法可用于多缩水甘油酯的合成，多缩水甘油酯是有价值的环氧树脂单体。机理研究表明，在非极性溶剂中缩水甘油与季烷基铵盐的结合络合物的形成，以及通过环氧化物的开环反应生成了作为催化剂的醇盐阴离子。对反应机理的计算研究表明，由缩水甘油产生的醇盐阴离子趋向于提取另一缩水甘油的质子，而不是作为亲核试剂起作用，从而引发了催化酯交换反应。由于阴离子和二醇之间存在双氢键，因此产生质子化的缩水甘油缩水甘油酯的Payne重排会产生不利于能量的不利反应，从而促进非选择性反应。季烷基铵阳离子和环氧化物部分之间的最小相互作用抑制了导致聚合的无规开环途径。由于阴离子和二醇之间的双氢键，在能量上不利。季烷基铵阳离子和环氧化

  DOI：

  10.1021/acscatal.7b03303

文献信息

• RESIN COMPOSITION AND MOLDED ARTICLE COMPRISING THE SAME
  申请人：TORAY INDUSTRIES, INC.

  公开号：EP1903077A1

  公开（公告）日：2008-03-26

  A resin composition comprising a polylactic acid-based resin (A) and methacrylic resins (B), wherein the methacrylic resins having at least (a) a difference of 10°C or more in glass transition temperature or (b) a difference of 3% or more in syndiotacticity; it is preferred that at least one of the methacrylic resins (B) is a methacrylic resin having a weight average molecular weight of 50,000 to 450,000, a glass transition temperature of 110°C or higher and a syndiotacticity of 40% or more, and that the resin composition further contains a multilayer structure polymer formed as particles each consisting of a core layer and one or more shell layers covering it (C). A molded article made of said resin composition.

  一种树脂组合物，包括聚乳酸基树脂（A）和甲基丙烯酸树脂（B），其中甲基丙烯酸树脂至少(a)在玻璃化转变温度上相差 10°C 或更多，或(b)在联合活度上相差 3% 或更多；优选至少一种甲基丙烯酸树脂 (B) 是重量平均分子量为 50,000 至 450,000 的甲基丙烯酸树脂，玻璃化温度为 110°C 或更高，辛二酸度为 40% 或更高，并且该树脂组合物还包含一种多层结构聚合物，该聚合物形成为颗粒，每个颗粒由芯层和覆盖在芯层上的一层或多层壳层组成 (C)。由所述树脂组合物制成的模塑制品。
• THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE THEREOF
  申请人：Toray Industries, Inc.

  公开号：EP2036952A1

  公开（公告）日：2009-03-18

  This invention relates to a thermoplastic resin composition and a molded article thereof, respectively excellent in flowability and mechanical properties, and, in a preferred mode, also excellent in low warping property, laser transmittance and laser weldability, and provides a thermoplastic resin composition obtained by mixing (B) 0.1 to 4 parts by weight of a polyfunctional compound having three or more functional groups, in which at least one of the terminal structures having the functional groups is a structure containing alkylene oxide units, with (A) 100 parts by weight of a thermoplastic resin, and further provides a molded particle thereof. It is preferred that the (A) thermoplastic resin is one or more selected from a polyester resin and polycarbonate resin.

  本发明涉及一种热塑性树脂组合物及其模塑制品，它们分别具有优异的流动性和机械性能，在优选模式下，还具有优异的低翘曲性能、激光透射率和激光可焊性，本发明提供了一种热塑性树脂组合物，该组合物是将(B)0.1 至 4 份（按重量计）具有三个或三个以上官能团的多官能团化合物与(A)100 份（按重量计）热塑性树脂混合而得，其中具有官能团的末端结构中至少有一个是含有环氧亚烷基单元的结构，本发明还进一步提供了其模塑颗粒。优选的是，(A) 热塑性树脂是从聚酯树脂和聚碳酸酯树脂中选出的一种或多种。
• THERMOPLASTIC RESIN COMPOSITION AND MOLDED ITEM FORMED FROM SAME
  申请人：Toray Industries, Inc.

  公开号：EP2524945A1

  公开（公告）日：2012-11-21

  Provided are a thermoplastic resin composition comprising 1 to 100 parts by weight of a flame retardant (B) containing any one or more flame retardants (B-1) selected from melamine phosphate, melamine pyrophosphate, and melamine polyphosphate and any one or more flame retardants (B-2) selected from piperazine phosphate, piperazine pyrophosphate, and piperazine polyphosphate, based on 100 parts by weight of a thermoplastic resin (A) comprising polylactide resin, wherein, according to transmission electronic microscopy, the major axis of the largest particle of the flame retardant (B) in the composition is not more than 10 µm, and the ratio of the number of particles of the flame retardant (B) having a major axis of not more than 3 µm relative to the number of particles of the flame retardant (B) per an area of 1,000 µm2 is 70% or more; a molded article made of the thermoplastic resin composition; and a thermoplastic resin composition having excellent molding processability, shock resistance, and heat resistance, in particular, excellent flame retardancy, and a molded article made of the same.

  提供了一种热塑性树脂组合物，该组合物包含 1 至 100 重量份的阻燃剂 (B)，其中阻燃剂 (B-1) 选自磷酸三聚氰胺、焦磷酸三聚氰胺和聚磷酸三聚氰胺，阻燃剂 (B-2) 选自磷酸哌嗪、焦磷酸哌嗪和聚磷酸哌嗪，以 100 重量份由聚乳酸树脂组成的热塑性树脂 (A) 为基础、其中，根据透射电子显微镜检测，组合物中阻燃剂（B）最大颗粒的主轴不超过 10 微米，且每 1,000 微米面积上主轴不超过 3 微米的阻燃剂（B）颗粒数与阻燃剂（B）颗粒数之比为 70% 或以上；由该热塑性树脂组合物制成的模制品；以及具有优异的成型加工性、抗冲击性和耐热性，尤其是优异的阻燃性的热塑性树脂组合物及其制成的模制品。
• Resin composition and molded article comprising of the same
  申请人：TORAY INDUSTRIES, INC.

  公开号：EP2740767A1

  公开（公告）日：2014-06-11

  The present invention concerns a resin composition comprising (A) a polylactic acid-based resin and (B) a methacrylic resin, wherein the ratio (syndiotacticity/isotacticity) of the syndiotacticity to the isotacticity of the methacrylic resin (B) in the resin composition is 3.0 to 8.0.

  本发明涉及一种树脂组合物，该树脂组合物由(A)聚乳酸基树脂和(B)甲基丙烯酸树脂组成，其中甲基丙烯酸树脂(B)在树脂组合物中的辛二酸与异辛二酸之比（辛二酸/异辛二酸）为 3.0 至 8.0。
• BIAXIALLY STRETCHED POLYESTER FILM, METHOD FOR PRODUCING SAME AND SOLAR CELL MODULE
  申请人：Fujifilm Corporation

  公开号：EP2749399A1

  公开（公告）日：2014-07-02

  Provided is a biaxially stretched polyester film in which a thickness is from 200 µm to 800 µm, fracture strength in both a longitudinal stretching direction and a lateral stretching direction is from 180 MPa to 300 MPa, an internal haze (Hin) is from 0.3% to 20%, a difference (ΔH = Hsur - Hin) between an external haze (Hsur) and the internal haze (Hin) is 2% or less, and an intrinsic viscosity is from 0.68 to 0.90, a method of the biaxially stretched polyester film, a solar cell power generation module using the biaxially stretched polyester film.

  提供了一种双轴拉伸聚酯薄膜，其厚度为 200 µm 至 800 µm，纵向拉伸方向和横向拉伸方向的断裂强度均为 180 MPa 至 300 MPa，内部雾度 (Hin) 为 0.3% 至 20%，外部雾度 (Hsur) 与内部雾度 (Hin) 之差 (ΔH = Hsur - Hin) 为 2% 或更小，固有粘度为 0.68 至 0.90，双轴拉伸聚酯薄膜的方法，使用双轴拉伸聚酯薄膜的太阳能电池发电模块。